Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ben C Collins"'
Autor:
Matteo Mori, Zhongge Zhang, Amir Banaei-Esfahani, Jean-Benoît Lalanne, Hiroyuki Okano, Ben C Collins, Alexander Schmidt, Olga T Schubert, Deok-Sun Lee, Gene-Wei Li, Ruedi Aebersold, Terence Hwa, Christina Ludwig
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 11, Pp 1257-1259 (2024)
Externí odkaz:
https://doaj.org/article/bf43447accd7475196f5d29faa787a0f
Autor:
Jelena Čuklina, Chloe H Lee, Evan G Williams, Tatjana Sajic, Ben C Collins, María Rodríguez Martínez, Varun S Sharma, Fabian Wendt, Sandra Goetze, Gregory R Keele, Bernd Wollscheid, Ruedi Aebersold, Patrick G A Pedrioli
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 8, Pp 1-16 (2021)
Abstract Advancements in mass spectrometry‐based proteomics have enabled experiments encompassing hundreds of samples. While these large sample sets deliver much‐needed statistical power, handling them introduces technical variability known as ba
Externí odkaz:
https://doaj.org/article/19902b50778d4e318c792e04483c0f07
Autor:
Matteo Mori, Zhongge Zhang, Amir Banaei‐Esfahani, Jean‐Benoît Lalanne, Hiroyuki Okano, Ben C Collins, Alexander Schmidt, Olga T Schubert, Deok‐Sun Lee, Gene‐Wei Li, Ruedi Aebersold, Terence Hwa, Christina Ludwig
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 5, Pp 1-23 (2021)
Abstract Accurate measurements of cellular protein concentrations are invaluable to quantitative studies of gene expression and physiology in living cells. Here, we developed a versatile mass spectrometric workflow based on data‐independent acquisi
Externí odkaz:
https://doaj.org/article/6aa5a86f417842f5b356db6414fccb62
Autor:
Moritz Heusel, Isabell Bludau, George Rosenberger, Robin Hafen, Max Frank, Amir Banaei‐Esfahani, Audrey van Drogen, Ben C Collins, Matthias Gstaiger, Ruedi Aebersold
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 1, Pp 1-22 (2019)
Abstract Proteins are major effectors and regulators of biological processes that can elicit multiple functions depending on their interaction with other proteins. The organization of proteins into macromolecular complexes and their quantitative dist
Externí odkaz:
https://doaj.org/article/94f8741ead474fbc9b1bd932e6cc5d80
Autor:
Christina Ludwig, Ludovic Gillet, George Rosenberger, Sabine Amon, Ben C Collins, Ruedi Aebersold
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 8, Pp 1-23 (2018)
Abstract Many research questions in fields such as personalized medicine, drug screens or systems biology depend on obtaining consistent and quantitatively accurate proteomics data from many samples. SWATH‐MS is a specific variant of data‐indepen
Externí odkaz:
https://doaj.org/article/212c63d12c084d8d8234958f755d97d2
Autor:
Yansheng Liu, Alfonso Buil, Ben C Collins, Ludovic CJ Gillet, Lorenz C Blum, Lin‐Yang Cheng, Olga Vitek, Jeppe Mouritsen, Genevieve Lachance, Tim D Spector, Emmanouil T Dermitzakis, Ruedi Aebersold
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 2, Pp 1-18 (2015)
Abstract The degree and the origins of quantitative variability of most human plasma proteins are largely unknown. Because the twin study design provides a natural opportunity to estimate the relative contribution of heritability and environment to d
Externí odkaz:
https://doaj.org/article/1f824790b47942e1aee2d6e5fce7ddf5
Autor:
Isabell Bludau, Max Frank, Christian Dörig, Yujia Cai, Moritz Heusel, George Rosenberger, Paola Picotti, Ben C. Collins, Hannes Röst, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Many proteins exist in various proteoforms but detecting these variants by bottom-up proteomics remains difficult. Here, the authors present a computational approach based on peptide correlation analysis to identify and characterize proteoforms from
Externí odkaz:
https://doaj.org/article/4bc622ef871944e7b4a94176e06f1144
Autor:
Wenguang Shao, Tiannan Guo, Nora C. Toussaint, Peng Xue, Ulrich Wagner, Li Li, Konstantina Charmpi, Yi Zhu, Jianmin Wu, Marija Buljan, Rui Sun, Dorothea Rutishauser, Thomas Hermanns, Christian Daniel Fankhauser, Cedric Poyet, Jelena Ljubicic, Niels Rupp, Jan H. Rüschoff, Qing Zhong, Andreas Beyer, Jiafu Ji, Ben C. Collins, Yansheng Liu, Gunnar Rätsch, Peter J. Wild, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Protein degradation in clinical samples is largely unexplored. Here, the authors analyze the transcriptome and proteome of clinical tissue samples and develop an algorithm to assess protein degradation, showing that protein degradation is negligible
Externí odkaz:
https://doaj.org/article/5e2fad9e30374816bb16c6dcb2619e1f
Autor:
Ben C. Collins, Christie L. Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Samuel L. Bader, Daniel W. Chan, Bradford W. Gibson, Anne-Claude Gingras, Jason M. Held, Mio Hirayama-Kurogi, Guixue Hou, Christoph Krisp, Brett Larsen, Liang Lin, Siqi Liu, Mark P. Molloy, Robert L. Moritz, Sumio Ohtsuki, Ralph Schlapbach, Nathalie Selevsek, Stefani N. Thomas, Shin-Cheng Tzeng, Hui Zhang, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
SWATH-mass spectrometry consists of a data-independent acquisition and a targeted data analysis strategy that aims to maintain the favorable quantitative characteristics on the scale of thousands of proteins. Here, using data generated by eleven grou
Externí odkaz:
https://doaj.org/article/44740b6f8c2d466ca5462d8455eae709
Autor:
Teresa Cortes, Olga T. Schubert, Amir Banaei-Esfahani, Ben C. Collins, Ruedi Aebersold, Douglas B. Young
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Mycobacterium tuberculosis has succeeded as a human pathogen for tens of thousands of years thanks to its ability to resist and adapt to the adverse conditions it encounters upon infection. Bacterial adaptation to stress is commonly viewed i
Externí odkaz:
https://doaj.org/article/6c777e17ef37415aa7763f9a16e8e9b1