Zobrazeno 1 - 10
of 550
pro vyhledávání: '"Ben Davidson"'
Autor:
Christin Lund-Andersen, Annette Torgunrud, Chakravarthi Kanduri, Vegar J. Dagenborg, Ida S. Frøysnes, Mette M. Larsen, Ben Davidson, Stein G. Larsen, Kjersti Flatmark
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Patients with peritoneal metastasis from colorectal cancer (PM-CRC) have inferior prognosis and respond particularly poorly to chemotherapy. This study aims to identify the molecular explanation for the observed clinical behavior
Externí odkaz:
https://doaj.org/article/7d52e77ca55b4a2c85c7fa8d071ee9c9
Autor:
Gunnar Kvalheim, Kristina Lindemann, Ben Davidson, Line Bjorge, Else Marit Inderberg, Sébastien Wälchli, Emmet McCormack, Katrin Kleinmanns, David J Warren, Erik Rokkones, Martine Lode, Nicholas P Casey, Christopher Forcados, Pascal F Gelebart, Sandy Joaquina, Emmanuelle Benard, Fatemeh Kaveh, Benjamin Caulier, Christiane Helgestad Gjerde, Elvira García de Jalón, Marit Renee Myhre
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies in the Western world. Contributing factors include a high frequency of late-stage diagnosis, the development of chemoresistance, and the evasion of host immune
Externí odkaz:
https://doaj.org/article/162ad2ed429c4bd1b84eb0e5bfee44ad
Autor:
Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, Joao A. G. Duarte, Esther A. Zaal, Ali Talebi, Matteo Rossi, Pierre-René Körner, Lara Rizzotto, Stijn Moens, Wout De Wispelaere, Regina E. M. Baiden-Amissah, Gabe S. Sonke, Hugo M. Horlings, Guy Eelen, Emanuele Berardi, Johannes V. Swinnen, Celia R. Berkers, Peter Carmeliet, Diether Lambrechts, Ben Davidson, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Metabolic reprogramming is associated with cancer development and therapy resistance. Here, the authors show that downregulation of the serine biosynthesis enzyme PHGDH in a fraction of patients is associated with relapse in platinum-treated ovarian
Externí odkaz:
https://doaj.org/article/ea6155ed60d848d191feda4d57429fb3
Autor:
Giorgia Sonzini, Sofia Granados-Aparici, Sabina Sanegre, Angel Diaz-Lagares, Juan Diaz-Martin, Carlos de Andrea, Núria Eritja, Aida Bao-Caamano, Nicolás Costa-Fraga, David García-Ros, Carmen Salguero-Aranda, Ben Davidson, Rafael López-López, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The incidence of new cancer cases is expected to increase significantly in the future, posing a worldwide problem. In this regard, precision oncology and its diagnostic tools are essential for developing personalized cancer treatments. Digital pathol
Externí odkaz:
https://doaj.org/article/1debe2f1f3eb466fb9188e4c9d95f9d3
Autor:
Ben Davidson, Kjersti Flatmark, Annette Torgunrud, Karianne G Fleten, Hedvig V Juul, Nadia Mensali, Christin Lund-Andersen, Else Marit Inderberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/4864f37ffe5d416d827db4a7ed822510
Autor:
Yu Yu, Yohan Suryo Rahmanto, Yao-An Shen, Laura Ardighieri, Ben Davidson, Stephanie Gaillard, Ayse Ayhan, Xu Shi, Jianhua Xuan, Tian-Li Wang, Ie-Ming Shih
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 184-194 (2019)
Background: Spleen tyrosine kinase (SYK) is frequently upregulated in recurrent ovarian carcinomas, for which effective therapy is urgently needed. SYK phosphorylates several substrates, but their translational implications remain unclear. Here, we s
Externí odkaz:
https://doaj.org/article/bee7cabc93c645bea57be3b17dc7add6
Autor:
Sabina Sanegre, Núria Eritja, Carlos de Andrea, Juan Diaz-Martin, Ángel Diaz-Lagares, María Amalia Jácome, Carmen Salguero-Aranda, David García Ros, Ben Davidson, Rafel Lopez, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular matrix and secreted fact
Externí odkaz:
https://doaj.org/article/743805c8e0f34b5ba6114838c5cfc6a8
Autor:
Renata L Muylaert, Ben Davidson, Alex Ngabirano, Gladys Kalema-Zikusoka, Hayley MacGregor, James O Lloyd-Smith, Ahmed Fayaz, Matthew A Knox, David T S Hayman
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0254467 (2021)
Cross-species transmission of pathogens is intimately linked to human and environmental health. With limited healthcare and challenging living conditions, people living in poverty may be particularly susceptible to endemic and emerging diseases. Simi
Externí odkaz:
https://doaj.org/article/bdf1558ca36f44799b98b31bea922974
Autor:
Katrin Kleinmanns, Vibeke Fosse, Ben Davidson, Elvira García de Jalón, Olav Tenstad, Line Bjørge, Emmet McCormack
Publikováno v:
EBioMedicine, Vol 56, Iss , Pp 102783- (2020)
Background: The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of peritoneal metastases during cyt
Externí odkaz:
https://doaj.org/article/96a8cedb63714f4aa7830068c37aac13
Autor:
Marianne Lislerud Smebye, Antonio Agostini, Bjarne Johannessen, Jim Thorsen, Ben Davidson, Claes Göran Tropé, Sverre Heim, Rolf Inge Skotheim, Francesca Micci
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in high-grade serous ovarian carcinomas and have been reported as a common
Externí odkaz:
https://doaj.org/article/87dbcd2ce34d4b30af8c842afc00eb0a