Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ben, Vaughn"'
Publikováno v:
Arthritis Care & Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d22d29745bede38922e28f0a19f4bf
https://doi.org/10.1002/acr.25142
https://doi.org/10.1002/acr.25142
Publikováno v:
Journal of Biopharmaceutical Statistics. 32:441-449
Randomization-based inference is a useful alternative to traditional population model-based methods. In trials with missing data, multiple imputation is often used. We describe how to construct a randomization test in clinical trials where multiple i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407aeeb0c979628947c96cac2b9a08ff
https://doi.org/10.1080/10543406.2022.2080695
https://doi.org/10.1080/10543406.2022.2080695
Autor:
Nathaniel F. Watson, Jeffrey M Dayno, Ben Vaughn, Donna Zarycranski, Craig W. Davis, Yves Dauvilliers, Jean-Charles Schwartz
Publikováno v:
CNS Drugs
Background Pitolisant is approved in the USA and Europe for the treatment of excessive daytime sleepiness or cataplexy in adults with narcolepsy. Objective Analyses evaluated the time to onset of clinical response during treatment with pitolisant. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe886b2ef564a766764b0b35d1d14ca
http://europepmc.org/articles/PMC8642365
http://europepmc.org/articles/PMC8642365
Publikováno v:
Sleep Medicine. 81:210-217
To evaluate the efficacy of pitolisant, a histamine 3 (HData were pooled from two randomized, placebo-controlled, 7- or 8-week studies of pitolisant (titrated to a potential maximum dose of 35.6 mg/day) in adults with narcolepsy. Analyses included th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5221cd5a5a6772bcf89b542666c5a752
https://doi.org/10.1016/j.sleep.2021.02.037
https://doi.org/10.1016/j.sleep.2021.02.037
Autor:
Alina C Beaton, Daneshvari Solanki, Hernan Salazar, Steve Folkerth, Neil Singla, Harold S Minkowitz, David Leiman, Ben Vaughn, Nina Skuban, Gwendolyn Niebler
Publikováno v:
Regional Anesthesia & Pain Medicine. :rapm-2022
IntroductionSurgical site infiltration with bupivacaine hydrochloride (HCl) is a standard element of postoperative analgesia for soft tissue surgeries, but results in short-lived analgesia. A novel bupivacaine implant, XARACOLL (bupivacaine HCl), is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe0271e42eb328a72dd7039581e3c157
https://doi.org/10.1136/rapm-2022-104110
https://doi.org/10.1136/rapm-2022-104110
Publikováno v:
Journal of Pain Research
Diana S Meske,1 Ben J Vaughn,2 Ernest A Kopecky,3 Nathaniel Katz4,5 1Collegium Pharmaceutical, Inc, Stoughton, MA, USA; 2Rho, Chapel Hill, NC, USA; 3Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, USA; 4WCG Analgesic Solutions, Wayland, MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201eb1ccd9d7e7e3228692c1a695a8aa
http://europepmc.org/articles/PMC6875508
http://europepmc.org/articles/PMC6875508
Autor:
Ernest A. Kopecky, Melinda O'Connor, Steven D Passik, John D. Markman, Ben Vaughn, Diana S Meske
Publikováno v:
Journal of Pain Research
JohnMarkman,1 Diana S Meske,2 Ernest A Kopecky,2 Ben Vaughn,3 Melinda L O’Connor,2 Steven D Passik2 1Department of Neurosurgery, Translational Pain Research Program, University of Rochester, Rochester, NY, USA; 2Collegium Pharmaceutical Inc., Canto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3361830deab15ef64734b8b0bb5d7be2
https://doi.org/10.2147/jpr.s168836
https://doi.org/10.2147/jpr.s168836
Publikováno v:
Drugs & Aging
Trial Design This was a phase III, randomized withdrawal, double-blind, placebo-controlled, enriched enrollment, parallel-group, multicenter study intended to demonstrate the safety, tolerability, and analgesic efficacy of oxycodone DETERx® (Xtampza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972a3555d639ee2a30fe3487084c75a5
http://europepmc.org/articles/PMC5541102
http://europepmc.org/articles/PMC5541102
Publikováno v:
Sleep. 43:A289-A290
Introduction Recent literature suggests that histamine may play an important role in narcolepsy. This post hoc analysis evaluates the efficacy of pitolisant, a histamine 3 (H3)-receptor antagonist/inverse agonist, in patients with high burden of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4b0252b9aca58679a3040ecc1d89d9
https://doi.org/10.1093/sleep/zsaa056.758
https://doi.org/10.1093/sleep/zsaa056.758
Publikováno v:
Sleep. 43:A291-A292
Introduction This analysis evaluated the efficacy of pitolisant over time in three 7- to 8-week, randomized, placebo-controlled studies of adults with narcolepsy. Methods Patients in all 3 studies (HARMONY-1, HARMONY-1bis, HARMONY-CTP) experienced ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d7b9b257c5461b8c3ac7fc4aae4af3
https://doi.org/10.1093/sleep/zsaa056.764
https://doi.org/10.1093/sleep/zsaa056.764