In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis

Autor: Africa, JA, Behling, CA, Brunt, EM, Zhang, N, Luo, Y, Wells, A, Hou, J, Belt, PH, Kohil, R, Lavine, JE, Molleston, JP, Newton, KP, Whitington, PF, Schwimmer, JB, Abrams, SH, Barlow, S, Himes, R, Krisnamurthy, R, Maldonado, L, Mahabir, R, Carr, A, Bernstein, K, Bramlage, K, Cecil, K, DeVore, S, Kohli, R, Lake, K, Podberesky, D, Towbin, A, Xanthakos, S, Behr, G, Lefkowitch, JH, Mencin, A, Reynoso, E, Alazraki, A, Cleeton, R, Cordero, M, Hernandez, A, Karpen, S, Munos, JC, Raviele, N, Vos, M, Bozic, M, Cummings, OW, Klipsch, A, Ragozzino, E, Sandrasegaran, K, Subbarao, G, Walker, L, Kafka, K, Scheimann, A, Ito, J, Fishbein, MH, Mohammad, S, Rigsby, C, Sharda, L, Cattoor, T, Derdoy, J, Freebersyser, J, Jain, A, King, D, Lai, J, Osmack, P, Siegner, J, Stewart, S, Torretta, S, Wriston, K, Baker, SS, Lopez-Graham, D, Williams, S, Zhu, L, Awai, H, Behling, C, Bross, C, Collins, J, Durelle, J, Harlow, K, Middleton, M, Paiz, M, Sirlin, C, Ugalde-Nicalo, P, Villarreal, MD, Aouizerat, B, Courtier, J, Ferrell, LD, Feier, N, Gill, R, Langlois, C

Publikováno v: Africa, JA; Behling, CA; Brunt, EM; Zhang, N; Luo, Y; Wells, A; et al.(2018). In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clinical Gastroenterology and Hepatology, 16(3), 438-446.e1. doi: 10.1016/j.cgh.2017.02.030. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2g75d87d

© 2018 AGA Institute Background & Aims: Focal zone 1 steatosis, although rare in adults with nonalcoholic fatty liver disease (NAFLD), does occur in children with NAFLD. We investigated whether focal zone 1 steatosis and focal zone 3 steatosis are d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::029886808946b362732bd9036efc8f0b
http://www.escholarship.org/uc/item/2g75d87d

Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.

Autor: Schwimmer JB; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California., Johnson JS; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut., Angeles JE; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Behling C; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Pathology, Sharp Medical Center, San Diego, California., Belt PH; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Borecki I; The McDonnell Genome Institute, Washington University in St. Louis, St. Louis, Missouri., Bross C; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Durelle J; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Goyal NP; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Hamilton G; Liver Imaging Group, Department of Radiology, University of California, San Diego, California., Holtz ML; Department of Pediatrics, Division of Gastroenterology, Medical College of Wisconsin, Milwaukee, Wisconsin; Center for Microbiome Research, Medical College of Wisconsin, Milwaukee, Wisconsin., Lavine JE; Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Columbia University, New York, New York., Mitreva M; The McDonnell Genome Institute, Washington University in St. Louis, St. Louis, Missouri., Newton KP; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California., Pan A; Department of Pediatrics, Division of Quantitative Health Sciences, The Medical College of Wisconsin, Milwaukee, Wisconsin., Simpson PM; Department of Pediatrics, Division of Quantitative Health Sciences, The Medical College of Wisconsin, Milwaukee, Wisconsin., Sirlin CB; Liver Imaging Group, Department of Radiology, University of California, San Diego, California., Sodergren E; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut., Tyagi R; The McDonnell Genome Institute, Washington University in St. Louis, St. Louis, Missouri., Yates KP; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Weinstock GM; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut., Salzman NH; Department of Pediatrics, Division of Gastroenterology, Medical College of Wisconsin, Milwaukee, Wisconsin; Center for Microbiome Research, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: nsalzman@mcw.edu.

Publikováno v: Gastroenterology [Gastroenterology] 2019 Oct; Vol. 157 (4), pp. 1109-1122. Date of Electronic Publication: 2019 Jun 27.

In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis.

Autor: Africa JA; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California., Behling CA; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Pathology, Sharp Memorial Hospital, San Diego, California., Brunt EM; Department of Pathology, Washington University, St. Louis, Missouri., Zhang N; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Luo Y; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California., Wells A; Clinical and Translational Research Institute, University of California San Diego School of Medicine, La Jolla, California., Hou J; Clinical and Translational Research Institute, University of California San Diego School of Medicine, La Jolla, California., Belt PH; Johns Hopkins University, Baltimore, Maryland., Kohil R; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Lavine JE; Department of Pediatrics, Columbia University, New York, New York., Molleston JP; Department of Pediatrics, Indiana University, Indianapolis, Indiana; James Whitcomb Riley Hospital, Indianapolis, Indiana., Newton KP; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California., Whitington PF; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois., Schwimmer JB; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California. Electronic address: jschwimmer@ucsd.edu.

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2018 Mar; Vol. 16 (3), pp. 438-446.e1. Date of Electronic Publication: 2017 Mar 07.