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Autor:
Patrick Boada, Benoit Fatou, Alexia A. Belperron, Tara K. Sigdel, Kinga K. Smolen, Zainab Wurie, Ofer Levy, Shannon E. Ronca, Kristy O. Murray, Juliane M. Liberto, Priyanka Rashmi, Maggie Kerwin, Ruth R. Montgomery, Linda K. Bockenstedt, Hanno Steen, Minnie M. Sarwal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Advancement in proteomics methods for interrogating biological samples has helped identify disease biomarkers for early diagnostics and unravel underlying molecular mechanisms of disease. Herein, we examined the serum proteomes of 23 study participan
Externí odkaz:
https://doaj.org/article/2f9560c2a25d4310b30fae2d44e980e4
Autor:
Han, Seungeun, Lubelczyk, Charles, Hickling, Graham J., Belperron, Alexia A., Bockenstedt, Linda K., Tsao, Jean I.
Publikováno v:
In Ticks and Tick-borne Diseases April 2019 10(3):682-689
Autor:
Ruoyi Jiang, Hailong Meng, Khadir Raddassi, Ira Fleming, Kenneth B. Hoehn, Kenneth R. Dardick, Alexia A. Belperron, Ruth R. Montgomery, Alex K. Shalek, David A. Hafler, Steven H. Kleinstein, Linda K. Bockenstedt
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick–transmitted Borreliella spirochetal infection known as Lyme disease. T cells and innate immune cells have previously been shown to predominate the EM lesion and promote the
Externí odkaz:
https://doaj.org/article/f707b263da164abface756aa19cc0bb0
Autor:
Melissa J. Caimano, Ashley M. Groshong, Alexia Belperron, Jialing Mao, Kelly L. Hawley, Amit Luthra, Danielle E. Graham, Christopher G. Earnhart, Richard T. Marconi, Linda K. Bockenstedt, Jon S. Blevins, Justin D. Radolf
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Maintenance of Borrelia burgdorferi within its enzootic cycle requires a complex regulatory pathway involving the alternative σ factors RpoN and RpoS and two ancillary trans-acting factors, BosR and Rrp2. Activation of this pathway occurs within tic
Externí odkaz:
https://doaj.org/article/18744cc3668a41179207794464d488a6
Publikováno v:
Journal of Student Research. 11
The role of B cells in skin inflammation highlights the versatility of B cells in their response to diverse immune stimuli perceived as external threats to the host. B cells play a vital role in the immune system’s ability to effectively respond to
Autor:
Harman, Michael W., Dunham-Ems, Star M., Caimano, Melissa J., Belperron, Alexia A., Bockenstedt, Linda K., Fu, Henry C., Radolf, Justin D., Wolgemuth, Charles W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2012 Feb . 109(8), 3059-3064.
Externí odkaz:
https://www.jstor.org/stable/41506892
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Arthritis in mice infected with the Lyme disease spirochete, Borrelia burgdorferi, results from the influx of innate immune cells responding to the pathogen in the joint and is influenced in part by mouse genetics. Production of inflammatory cytokine
Externí odkaz:
https://doaj.org/article/074298dd053c4a41b55e6bbe2053f285
Autor:
Jessica M Dunn, Peter J Krause, Stephen Davis, Edouard G Vannier, Meagan C Fitzpatrick, Lindsay Rollend, Alexia A Belperron, Sarah L States, Andrew Stacey, Linda K Bockenstedt, Durland Fish, Maria A Diuk-Wasser
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115494 (2014)
Babesia microti and Borrelia burgdorferi, the respective causative agents of human babesiosis and Lyme disease, are maintained in their enzootic cycles by the blacklegged tick (Ixodes scapularis) and use the white-footed mouse (Peromyscus leucopus) a
Externí odkaz:
https://doaj.org/article/8c15dcecbc6a4f2fa8b2f0d06a5a577a
Autor:
Steven H. Kleinstein, Alex K. Shalek, David A. Hafler, Kenneth R. Dardick, Ruth R. Montgomery, Ira Fleming, Hailong Meng, Kenneth B. Hoehn, Linda K. Bockenstedt, Khadir Raddassi, Ruoyi Jiang, Alexia A. Belperron
Publikováno v:
JCI Insight
The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick-transmitted Borreliella spirochetal infection known as Lyme disease. T cells and innate immune cells have previously been shown to predominate the EM lesion and promote the r