Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Beloussow, A."'
Publikováno v:
Cancer Letters. 231:30-35
Arginine deiminase (ADI), currently in clinical trials, has various biological activities including anti-proliferation, anti-angiogenesis and inhibition of inducible nitric oxide synthase (iNOS). To recognize limitations and therapeutic applications,
Autor:
Karin Beloussow, Li-Jiuan Shen, Wen Chun Lin, Wei-Chiang Shen, David K. Ann, Ken Ichi Hosoya, Tetsuya Terasaki
Publikováno v:
Biochemical Pharmacology. 66:1945-1952
Modulation of the extracellular level of arginine, substrate for nitric oxide synthetases, is a promising modality to alleviate certain pathological conditions where excess nitric oxide (NO) is produced. However, complications arise, as only preferen
Publikováno v:
Cell and Tissue Research. 312:313-318
The iron carrier protein transferrin plays a prominent antioxidant and anti-bacterial role in the lower respiratory tract and is present at elevated concentrations in lung epithelial lining fluid relative to plasma. The level of transferrin receptor
Publikováno v:
Cancer Letters. 183:155-162
Arginine deiminase (ADI), isolated from Mycoplasma cell extracts, has been suggested to inhibit endothelial cell growth in vitro. However, anti-angiogenic activity by ADI has not yet been demonstrated. In this study, we investigated the in vitro effe
Publikováno v:
Journal of Inorganic and Organometallic Polymers. 10:51-60
The chemotherapeutic treatment of secondary, i.e., disseminated cancers, has until now remained an unsatisfactory modality. The LNCaP human metastatic prostate adenocarcinoma cell line lends itself as a useful tool to probe the efficaciousness of nov
Publikováno v:
Biochemical pharmacology. 69(1)
This study investigates our hypothesis that argininosuccinate synthase (AS), the rate-limiting enzyme for arginine (L-arg) regeneration from citrulline (L-cit), plays a pivotal role in supplying L-arg to endothelial (eNOS), but not inducible (iNOS) n
Publikováno v:
Cancer letters. 164(2)
The chemopreventive effects of Bowman-Birk protease inhibitor (BBI), a soybean polypeptide, and its palmitic acid conjugate, Pal-BBI, on 7,12-dimethylbenz[a]anthracene (DMBA)-induced transformation were investigated by using an in vitro whole organ c
Publikováno v:
In Cancer Letters 2006 231(1):30-35
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Akademický článek
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