Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bella Gurvits"'
Publikováno v:
International Journal of Biological Macromolecules. 55:62-68
New evidence for dynamic behavior and flexible oligomeric structure of the molecular chaperone α-crystallin is presented. Based on the results of laser dynamic light scattering, centrifugal ultrafiltration, size exclusion chromatography, analytical
Publikováno v:
FEBS Letters. 586:186-190
A striking potential of the amphiphilic dipeptides, Arg-Phe or Asp-Phe, to induce aggregation of a model protein, alcohol dehydrogenase in its native-like state, has been demonstrated under physiologically relevant conditions, using dynamic light sca
Publikováno v:
International Journal of Molecular Sciences, Vol 11, Iss 11, Pp 4556-4579 (2010)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 11; Issue 11; Pages: 4556-4579
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 11; Issue 11; Pages: 4556-4579
The kinetics of dithiothreitol (DTT)-induced aggregation of human recombinant insulin and the effect of α-crystallin, a representative of the family of small heat shock proteins, on the aggregation process have been studied using dynamic light scatt
Autor:
I. K. Yudin, Zoya M. Bumagina, Boris I. Kurganov, Bella Gurvits, Natalya V. Artemova, K. O. Muranov
Publikováno v:
Biophysical Chemistry. 146:108-117
The kinetics of dithiothreitol (DTT)-induced aggregation of alpha-lactalbumin from bovine milk has been studied using dynamic light-scattering technique. Analysis of the distribution of the particles formed in the solution of alpha-lactalbumin after
Publikováno v:
Biochemical and Biophysical Research Communications. 377:595-599
Protein misfolding and aggregation is one of the most serious problems in cell biology, molecular medicine, and biotechnology. Misfolded proteins interact with each other or with other proteins in non-productive or damaging ways. However, a new parad
Publikováno v:
Biotechnology Progress. 23:1411-1416
Prevention of undesirable protein aggregation is an extremely important strategy in protein science, medicine, and biotechnology. Arginine is one of the most widely used low molecular weight solution additives effective in suppressing aggregation, as
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 38:43-55
Macrophage migration inhibitory factor is a ubiquitous multifunctional cytokine having diverse immunological and neuroendocrine properties. Although this protein is known to be released into the circulation from the secretory granules of anterior pit
Autor:
Vita Stein-Margolina, Ekaterina Smirnova, Bella Gurvits, Vladimir Shubin, Irina V. Safenkova, Vladimir I. Polshakov
Publikováno v:
Biochimie. 109
Over the past two decades, much information has appeared on electrostatically driven molecular mechanisms of protein self-assembly and formation of aggregates of different morphology, varying from soluble amorphous structures to highly-ordered amyloi
Publikováno v:
International journal of pharmaceutics. 471(1-2)
The objective of this study is to elucidate the role of low-molecular weight biogenic agents, resembling dietary-derived products naturally occurring in the intestine, in the regulation of transformations of soluble aggregation-prone insulin into agg