A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

Autor: Timmers, Matt, Weterings, Jimmy, Van Geijn, Michiel, Bell, Roel, Lenting, Peter E., Rijcken, Cristianne J.F., Vermonden, Tina, Hennink, Wim E., Liskamp, Rob M.J., Afd Pharmaceutics, Sub Drug delivery, Afd Chemical Biology and Drug Discovery, Pharmaceutics, Chemical Biology and Drug Discovery

Publikováno v: Bioconjugate Chemistry, 33(9), 1707. American Chemical Society : Division of Carbohydrate Chemistry
Bioconjugate Chemistry, 33(9), 1707-1715. American Chemical Society

Core-cross-linked polymeric micelles (CCPMs) are a promising nanoparticle platform due to favorable properties such as their long circulation and tumor disposition exploiting the enhanced permeability and retention (EPR) effect. Sustained release of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279a4b9bd957d432b8567f6183b353cb
https://dspace.library.uu.nl/handle/1874/424173

Lipase-mediated resolution of octahydro-3,3,8a-trimethyl-1-naphthalenol, a key intermediate in the total synthesis of lactaranes and marasmanes

Autor: Franssen, Maurice C.R. ^{a, *}, Jongejan, Hugo ^a, Kooijman, Huub ^b, Spek, Anthony L. ^b, Bell, Roel P.L. ^a, Wijnberg, Joannes B.P.A. ^a, de Groot, Aede ^a

Publikováno v: In Tetrahedron: Asymmetry 1999 10(14):2729-2738

Base-induced rearrangement of perhydronaphthalene-1,4-diol monosulfonate esters to 11-...

Autor: Bell, Roel P.L., Sobolev, Arkadij, Wijnberg, Joannes B. P. A., de Groot, Aede

Publikováno v: Journal of Organic Chemistry; 01/09/98, Vol. 63 Issue 1, p122, 7p, 7 Diagrams

ChemInform Abstract: A Novel Route to the Marasmane Skeleton via a Tandem Rearrangement-Cyclopropanation Reaction. Total Synthesis of (+)-Isovelleral.

Autor: Bell, Roel P. L., Wijnberg, Joannes B. P. A., de Groot, Aede

Publikováno v: ChemInform; Aug2001, Vol. 32 Issue 34, pno-no, 1p

A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group.

Autor: Timmers M; Cristal Therapeutics, Maastricht 6229 EV, The Netherlands.; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands., Weterings J; Cristal Therapeutics, Maastricht 6229 EV, The Netherlands., van Geijn M; Cristal Therapeutics, Maastricht 6229 EV, The Netherlands., Bell R; Symeres, Nijmegen 6546 BB, The Netherlands., Lenting PE; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, U.K., Rijcken CJF; Cristal Therapeutics, Maastricht 6229 EV, The Netherlands., Vermonden T; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands., Hennink WE; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands., Liskamp RMJ; Cristal Therapeutics, Maastricht 6229 EV, The Netherlands.; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, U.K.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 ER, The Netherlands.

Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2022 Sep 21; Vol. 33 (9), pp. 1707-1715. Date of Electronic Publication: 2022 Aug 18.