Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism.

Autor: Li Z; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Votava JA; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Zajac GJM; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Nguyen JN; Department of Statistics, University of Wisconsin-Madison, Madison, WI, USA., Leyva Jaimes FB; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Ly SM; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Brinkman JA; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., De Giorgi M; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Kaul S; Department of Medicine, Division of Endocrinology, Medical College of Wisconsin, Milwaukee, WI, USA., Green CL; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., St Clair SL; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Belisle SL; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Rios JM; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Nelson DW; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Sorci-Thomas MG; Department of Medicine, Division of Endocrinology, Medical College of Wisconsin, Milwaukee, WI, USA., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Lamming DW; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Eric Yen CL; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA., Parks BW; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: brian.w.parks@wisc.edu.

Publikováno v: Cell metabolism [Cell Metab] 2020 Apr 07; Vol. 31 (4), pp. 741-754.e5. Date of Electronic Publication: 2020 Mar 19.