Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Belisa Parmeggiani"'
Autor:
Isadora Matias, Luan Pereira Diniz, Ana Paula Bergamo Araujo, Isabella Vivarini Damico, Pâmella de Moura, Felipe Cabral-Miranda, Fabiola Diniz, Belisa Parmeggiani, Valeria de Mello Coelho, Renata E. P. Leite, Claudia K. Suemoto, Gustavo Costa Ferreira, Regina Célia Cussa Kubrusly, Flávia Carvalho Alcantara Gomes
Publikováno v:
ASN Neuro, Vol 15 (2023)
Aging is marked by complex and progressive physiological changes, including in the glutamatergic system, that lead to a decline of brain function. Increased content of senescent cells in the brain, such as glial cells, has been reported to impact cog
Externí odkaz:
https://doaj.org/article/a97d7ca348904013a93951594460c987
Autor:
Nícolas Manzke Glänzel, Belisa Parmeggiani, Mateus Grings, Bianca Seminotti, Morgana Brondani, Larissa D. Bobermin, César A. J. Ribeiro, André Quincozes-Santos, Jerry Vockley, Guilhian Leipnitz
Publikováno v:
Cells, Vol 12, Iss 12, p 1557 (2023)
Sulfite predominantly accumulates in the brain of patients with isolated sulfite oxidase (ISOD) and molybdenum cofactor (MoCD) deficiencies. Patients present with severe neurological symptoms and basal ganglia alterations, the pathophysiology of whic
Externí odkaz:
https://doaj.org/article/ffe6e30328024464a374427db0517c37
Autor:
Leipnitz, Nícolas Manzke Glänzel, Belisa Parmeggiani, Mateus Grings, Bianca Seminotti, Morgana Brondani, Larissa D. Bobermin, César A. J. Ribeiro, André Quincozes-Santos, Jerry Vockley, Guilhian
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1557
Sulfite predominantly accumulates in the brain of patients with isolated sulfite oxidase (ISOD) and molybdenum cofactor (MoCD) deficiencies. Patients present with severe neurological symptoms and basal ganglia alterations, the pathophysiology of whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::112ae7f9bba8a6b268443e6f96af8f46
Autor:
Rômulo Rodrigo de Souza Almeida, Larissa Daniele Bobermin, Belisa Parmeggiani, Krista Minéia Wartchow, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Moacir Wajner, Guilhian Leipnitz, André Quincozes-Santos
Publikováno v:
Amino Acids. 54:1505-1517
Methylmalonic acidemia is a neurometabolic disorder biochemically characterized by the accumulation of methylmalonic acid (MMA) in different tissues, including the central nervous system (CNS). In this sense, it has been shown that high levels of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deb012831c283a98e993b097bdea73a
https://doi.org/10.1007/s00726-022-03191-z
https://doi.org/10.1007/s00726-022-03191-z
Autor:
Virginia Cielo Rech, Guilhian Leipnitz, Juliane Bolzan, Francine R. Ianiski, Barbara Dotto Fontana, Renata Garcez, Mateus Grings, Belisa Parmeggiani, Clovis Milton Duval Wannmacher, Nathana Jamille Mezzomo, Itiane Diehl de Franceschi, Rodrigo de Almeida Vaucher, Liana da Silva Fernandes, Diego Becker Borin
Publikováno v:
Molecular Biology Reports. 46:5897-5908
Phenylketonuria (PKU) is a metabolic disorder accumulating phenylalanine (Phe) and its metabolites in plasma and tissues of the patients. Regardless of the mechanisms, which Phe causes brain impairment, are poorly understood, energy deficit may have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459d315b766528243016891925d339a3
https://doi.org/10.1007/s11033-019-05023-y
https://doi.org/10.1007/s11033-019-05023-y
Autor:
Guilhian Leipnitz, Belisa Parmeggiani, Cristiane Cecatto, Renata Britto, Alexandre Umpierrez Amaral, Larissa Daniele Bobermin, Moacir Wajner, Nícolas Manzke Glänzel, Nevton Teixeira da Rosa-Junior, Leonardo de Moura Alvorcem
Publikováno v:
Mitochondrion. 47:141-150
We report here the effects of hydrogen sulfide (sulfide), that accumulates in ETHE1 deficiency, in rat cerebellum. Sulfide impaired electron transfer and oxidative phosphorylation. Sulfide also induced mitochondrial swelling, and decreased ΔΨm and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debc77d22adba524a2991836f01fa287
https://doi.org/10.1016/j.mito.2018.11.001
https://doi.org/10.1016/j.mito.2018.11.001
Autor:
Nevton Teixeira da Rosa-Junior, Belisa Parmeggiani, Nícolas Manzke Glänzel, Leonardo de Moura Alvorcem, Morgana Brondani, Renata Britto, Mateus Grings, Vanessa Duarte Ortiz, Patrick Turck, Alex Sander da Rosa Araujo, Moacir Wajner, Guilhian Leipnitz
Publikováno v:
European Journal of Pharmacology. 924:174950
Barth syndrome (BTHS) and dilated cardiomyopathy with ataxia syndrome (DCMA) are biochemically characterized by high levels of 3-methylglutaric acid (MGA) in the urine and plasma of affected patients. Although cardiolipin abnormalities have been obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ad899cb732e2450de0d289a214e91a
https://doi.org/10.1016/j.ejphar.2022.174950
https://doi.org/10.1016/j.ejphar.2022.174950
Autor:
Belisa Parmeggiani, Virgínia Mendes Carregal, Adriane Belló-Klein, Cristina Campos-Carraro, Jéssica Hellen Poletto Bonetto, Ionara Rodrigues Siqueira, Guilhian Leipnitz, Giana Blume Corssac, Laura Reck Cechinel, André R. Massensini, Mateus Grings, Alexsandra Zimmer
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 44(8)
Pulmonary arterial hypertension (PAH) is characterized by increased resistance of the pulmonary vasculature and afterload imposed on the right ventricle (RV). Two major contributors to the worsening of this disease are oxidative stress and mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c53e3cea68798f07d9b5668360f7a9
https://pubmed.ncbi.nlm.nih.gov/33875858
https://pubmed.ncbi.nlm.nih.gov/33875858
Autor:
Guilhian Leipnitz, Jaqueline Nascimento Picada, Débora Gonçalves Aguirre, Nayane Mendes Dos Santos, Dinara Jaqueline Moura, Verônica Bidinotto Brito, Fernanda Marcelia Dos Santos, Pricila Pflüger, Belisa Parmeggiani, Letícia Lazzarotto, Gabriela Gregory Regner, Marina Rocha Frusciante, Patrícia Pereira
Publikováno v:
Fundamentalclinical pharmacologyReferences. 35(2)
This study evaluated the effect of lacosamide (LCM) on biochemical and mitochondrial parameters after PTZ kindling in mice. Male mice were treated on alternative days for a period of 11 days with LCM (20, 30, or 40 mg/kg), saline, or diazepam (2 mg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb19491f449f3ae7060f67d83e717885
https://pubmed.ncbi.nlm.nih.gov/32851690
https://pubmed.ncbi.nlm.nih.gov/32851690
Autor:
Adriana Dillenburg Meinhart, Carla C. Zeppenfeld, Carine F. Souza, Osmar D. Prestes, Matheus D. Baldissera, Aleksandro S. Da Silva, Belisa Parmeggiani, Raquel G. Vendrusculo, Renato Zanella, Bernardo Baldisserotto, Lucila C. Ribeiro, Guilhian Leipnitz, Daniela K. Muenchen, Roger Wagner
Publikováno v:
Ecotoxicology and environmental safety. 205
Trichlorfon is an organophosphate insecticide that is widely used on fish farms to control parasitic infections. It has been detected in freshwater ecosystems as well as in fishery products. There is a growing body of evidence to suggest that certain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee7701b5c6dd591891809f8f1e14c3f
https://pubmed.ncbi.nlm.nih.gov/32846293
https://pubmed.ncbi.nlm.nih.gov/32846293