Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Belinda S. Harris"'
Autor:
John P Sundberg, Hannah Galantino-Homer, Heather Fairfield, Patricia F Ward-Bailey, Belinda S Harris, Melissa Berry, C Herbert Pratt, Nicholas E Gott, Lesley S Bechtold, Pauline R Kaplan, Blythe P Durbin-Johnson, David M Rocke, Robert H Rice
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0277284 (2022)
Numerous single gene mutations identified in humans and mice result in nail deformities with many similarities between the species. A spontaneous, autosomal, recessive mutation called witch nails (whnl) is described here where the distal nail matrix
Externí odkaz:
https://doaj.org/article/111ba92ac4f542d2b3f9392424ccbb91
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168159 (2016)
Otitis media (OM), inflammation of the middle ear, is a common cause of hearing loss in children and in patients with many different syndromic diseases. Studies of the human population and mouse models have revealed that OM is a multifactorial diseas
Externí odkaz:
https://doaj.org/article/fd58f69e50d6433d96828e3146d98905
Autor:
Li Yang, Belinda S. Harris, Luis F. Queme, Stacey J. Sukoff Rizzo, Taosheng Huang, Torrian Green, Jesse Slone, Michael P. Jankowski, Laura G. Reinholdt, Yanyan Peng, Jennifer L Ryan
Publikováno v:
Cell Death and Disease, Vol 11, Iss 6, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
The mitochondrial flavoprotein ferredoxin reductase (FDXR) is required for biogenesis of iron–sulfur clusters and for steroidogenesis. Iron–sulfur (Fe–S) clusters are ubiquitous cofactors essential to various cellular processes, and an increasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c9937eac8b186e181aca1c5ed8ac4b
http://link.springer.com/article/10.1038/s41419-020-2637-3
http://link.springer.com/article/10.1038/s41419-020-2637-3
Autor:
R Dee Schramm, Shuai Li, Belinda S Harris, Ryan P Rounds, Robert W Burgess, F Marty Ytreberg, Peter G Fuerst
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52652 (2012)
The differential adhesion hypothesis of development states that patterning of organisms, organs and tissues is mediated in large part by expression of cell adhesion molecules. The cues provided by cell adhesion molecules are also hypothesized to faci
Externí odkaz:
https://doaj.org/article/20ee404db52f4c2c8417125dd22531a1
Autor:
Elizabeth A. Sellars, Adam C. Chamberlin, Laura Gonzalez-Krellwitz, Yanyan Peng, Marie T. McDonald, Taosheng Huang, Julie Kaylor, Belinda S. Harris, Allyn McConkie-Rosell, Dmitry Tchapyjnikov, Laura G. Reinholdt, Monica E. Lemmon, Jesse Slone, Mays A. El-Dairi
Publikováno v:
Journal of human genetics. 63(12)
Mitochondrial dysfunction lies behind many neurodegenerative disorders, owing largely to the intense energy requirements of most neurons. Such mitochondrial dysfunction may work through a variety of mechanisms, from direct disruption of the electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be243cdbf11d2c54700099edb76e3a87
https://pubmed.ncbi.nlm.nih.gov/30250212
https://pubmed.ncbi.nlm.nih.gov/30250212
Autor:
Steven Sparagana, Jun Song Mo, Taosheng Huang, Belinda S. Harris, Matthew Bower, Francisca Milan, Zhuo Li, Adam C. Chamberlin, Rachel Brockhage, C. Alexander Valencia, Brenda Alvarez-Leon, Maria Renee Plona, Laura C. Anderson, James B. Gibson, Torrian Green, Yanyan Peng, Deepali N. Shinde, Stacey J. Sukoff Rizzo, Laura G. Reinholdt, Sha Tang, Shuk Ching Chong, Fernando Scaglia, Rebecca Willaert, Megan T. Cho, Peter Heydemann, Andrea M. Lewis, Baoheng Gui, George E. Hoganson, Elizabeth A. Sellars, Solange Gril, Jiani Chen, Jennifer Keller-Ramey, Kristin G. Monaghan, Zöe Powis, Katherine L. Helbig, Jie Liu, Alice Basinger, Min-Xin Guan, Rich Dineen, Jill A. Rosenfeld, Julie Kaylor, Pilar L. Magoulas
Publikováno v:
Human Molecular Genetics
Iron–sulfur (Fe-S) clusters are ubiquitous cofactors essential to various cellular processes, including mitochondrial respiration, DNA repair, and iron homeostasis. A steadily increasing number of disorders are being associated with disrupted bioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c59abd4d0e2116c9040e6362af66103
http://europepmc.org/articles/PMC5985726
http://europepmc.org/articles/PMC5985726
Autor:
Priscilla W. Lane, Leonard D. Shultz, Belinda S. Harris, Joachim Thiery, Bonnie L. Lyons, Leah Rae Donahue, Joseph E. Italiano, Oded Foreman, Roderick T. Bronson, Bruce Gott, Jonathan N. Thon, Kenneth R. Johnson, Henning Wittenburg, Uta Ceglarek, Lisa M. Burzenski, Thomas H. Chase
Publikováno v:
Blood. 115:1267-1276
The spontaneous mouse mutation “thrombocytopenia and cardiomyopathy” (trac) causes macrothrombocytopenia, prolonged bleeding times, anemia, leukopenia, infertility, cardiomyopathy, and shortened life span. Homozygotes show a 20-fold decrease in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668a3ce9ed0e0ee9c36e1d99cf94630a
https://doi.org/10.1182/blood-2009-05-219808
https://doi.org/10.1182/blood-2009-05-219808
Autor:
Bo Chang, Kenneth R. Johnson, Michael G. Anderson, Mao Mao, Daniel R. Thedens, Qing Yin Zheng, Leah Rae Donahue, Belinda S. Harris
Publikováno v:
Mammalian Genome. 20:462-475
Podosome-type adhesions are actin-based membrane protrusions involved in cell-matrix adhesion and extracellular matrix degradation. Despite growing knowledge of many proteins associated with podosome-type adhesions, much remains unknown concerning th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b611b61226726ce8b1c0f19653057c
https://doi.org/10.1007/s00335-009-9210-9
https://doi.org/10.1007/s00335-009-9210-9
Autor:
Laura G. Reinholdt, Amira Masri, Patricia F Ward-Bailey, Abby Tadenev, Jocelyn C. Sharp, Anne Czechanski, Robert W. Burgess, Candice Byers, Anuj Srivastava, Jeffrey Milbrandt, Belinda S. Harris, Hanan Hamamy, Periklis Makrythanasis, Stylianos E. Antonarakis, Gregory A. Cox, Rangjiao Liu, Stephen A. Murray, Coleen Kane, Jay Shendure, Whitney Martin, Polyxeni Gudis, Federico Santoni, Bo Chang, Anuradha Lakshminarayana, Paul F. Cliften, Laurent P. Bogdanik, Ian Greenstein, Kristina Palmer, Louise A Dionne, Heather Fairfield, Martin Kircher, C. Herbert Pratt, Son Yong Karst, Melissa L. Berry, David E. Bergstrom, Michelle Curtain, Leah Rae Donahue, Guruprasad Ananda, David G. Schroeder
Publikováno v:
Genome Research, Vol. 25, No 7 (2015) pp. 948-957
Genome Res, vol. 25, no. 7, pp. 948-57
GENOME RESEARCH
Genome Res, vol. 25, no. 7, pp. 948-57
GENOME RESEARCH
Spontaneously arising mouse mutations have served as the foundation for understanding gene function for more than 100 years. We have used exome sequencing in an effort to identify the causative mutations for 172 distinct, spontaneously arising mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d929619ef8a01cd99b8ef1fb6b5e99
https://europepmc.org/articles/PMC4484392/
https://europepmc.org/articles/PMC4484392/
Autor:
David E. Bergstrom, C. Herbert Pratt, Soheil S. Dadras, Paul N. Schofield, Laura G. Reinholdt, Belinda S. Harris, Bruce T. Liang, Christopher S. Potter, John P. Sundberg, Ian Greenstein, Heather Fairfield
Studies of spontaneous mutations in mice have provided valuable disease models and important insights into the mechanisms of human disease. Ruffled (rul) is a new autosomal recessive mutation causing abnormal hair coat in mice. The rul allele arose s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c1189f964888750282358c52c7d5f1
https://europepmc.org/articles/PMC4388778/
https://europepmc.org/articles/PMC4388778/