Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Belinda Mary Kumpel"'
Autor:
Andrew G. Hadley, Belinda Mary Kumpel
Publikováno v:
Baillière's Clinical Haematology. 6:423-444
Recent insights into the structure-function relationship of IgG, the nature of Fc receptors and their interactions with antibodies, and the cellular mechanisms involved in the immune destruction of IgG-sensitized cells have all contributed to a fulle
Heterogeneity in the ability of IgG1 monoclonal anti-D to promote lymphocyte-mediated red cell lysis
Autor:
Nevin C. Hughes-Jones, Andrew G. Hadley, Belinda Mary Kumpel, Benjamin Arthur De Burgh Bradley, Anthony H. Merry, Katherine A. Leader, Dominique Goossens, Antoine Blancher, Geoffrey D. Poole
Publikováno v:
European journal of immunology. 19(12)
Thirty-four IgG anti-D human monoclonal antibodies (mAb) derived from 18 donor were assessed for their ability to mediate lysis of D+ red cells by lymphocytes in antibody-dependent cell-mediated cytotoxicity assays. Cell-bound antibody was quantified