Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Belinda M. Kumpel"'
Publikováno v:
Transfusion. 48:2077-2086
BACKGROUND: Fetal and neonatal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a more commonly occurs in first pregnancies, unlike hemolytic disease of the newborn. Anti-D is produced after D+ fetomaternal hemorrhage; this usual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8cf2723d45000babb4ad3fdc37d436
https://doi.org/10.1111/j.1537-2995.2008.01832.x
https://doi.org/10.1111/j.1537-2995.2008.01832.x
Autor:
Belinda M. Kumpel
Publikováno v:
Immunology Letters. 82:67-73
Anti-D prophylaxis is the most successful clinical application of antibody-mediated immune suppression. Passive IgG anti-D is given to Rh D-negative women to prevent immunisation to foetal Rh D-positive red blood cells (RBC) and subsequent haemolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2794886379411582092110b52cd71ea7
https://doi.org/10.1016/s0165-2478(02)00020-2
https://doi.org/10.1016/s0165-2478(02)00020-2
Publikováno v:
Trends in Immunology. 22:26-31
During pregnancy, women can be immunized by fetal red blood cells (RBCs) of an incompatible blood group. Subsequent transplacental passage of the antibodies can result in fetal morbidity or mortality due to RBC destruction. The administration of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8831a5de88e083ac75eba686780447f
https://doi.org/10.1016/s1471-4906(00)01801-9
https://doi.org/10.1016/s1471-4906(00)01801-9
Publikováno v:
Transfusion. 40:228-239
BACKGROUND: A comparison was made between flow cytometric and conventional radioisotopic assays in the determination of the clearance or survival of small volumes of 51chromium-labeled D+ red cells after injection into volunteers. STUDY DESIGN AND ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d619e9d351295f29c7856965c6316b
https://doi.org/10.1046/j.1537-2995.2000.40020228.x
https://doi.org/10.1046/j.1537-2995.2000.40020228.x
Autor:
David J. Jackson, Belinda M. Kumpel
Publikováno v:
Human Antibodies. 8:181-188
A strategy for the production of human antibodies to tetanus toxoid (TT) is described. Human peripheral blood lymphocytes (PBL) were injected into severe combined immunodeficient (SCID) mice (termed hu-PBL-SCID) and the mice subsequently immunised wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca6ebd8582da9fcb2ac27a9789a1157
https://doi.org/10.3233/hab-1997-8403
https://doi.org/10.3233/hab-1997-8403
Autor:
Jeffrey A. Jones, R. Stamps, Clarissa Pilkington, Barbara Zupanska, R J Sokol, Andrew G. Hadley, Katherine A. Leader, Helen L. Griffiths, Belinda M. Kumpel, D J Booker
Publikováno v:
British Journal of Haematology. 91:587-594
Factors governing the functional activity of red cell autoantibodies are poorly defined. Here we report the presence of qualitative differences in the glycosylation of IgG autoantibodies which affect in vitro interactions with Fc gamma RIII. The foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28705211892f62d314de50b2df725c8
https://doi.org/10.1111/j.1365-2141.1995.tb05352.x
https://doi.org/10.1111/j.1365-2141.1995.tb05352.x
Autor:
DJ Anstee, GE Chapman, CV Morse, I. D. Fraser, G. D. Poole, D.H. Pamphilon, M.J. Goodrick, Belinda M. Kumpel, DP Thomas, Graham R. Standen
Publikováno v:
Blood. 86:1701-1709
The use of prophylactic anti-D to prevent Rh D immunization in Rh D- women and subsequent hemolytic disease in Rh D+ infants is widespread, but has led to shortages of the anti-D Ig. With the aim of substituting monoclonal anti-D for Rh D prophylaxis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4612e6271b1e48565ca8c9b12e686fe2
https://doi.org/10.1182/blood.v86.5.1701.bloodjournal8651701
https://doi.org/10.1182/blood.v86.5.1701.bloodjournal8651701
Publikováno v:
Human Antibodies. 6:82-88
The contribution to IgG effector function of exposed galactose residues on the oligosaccharide chains in IgG has been tested experimentally. We studied a human monoclonal antibody (BRAD-5) to the Rh D blood group antigen. The preparation used contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962fdb6b9f9d765f7884566dc1196be8
https://doi.org/10.3233/hab-1995-6301
https://doi.org/10.3233/hab-1995-6301
Publikováno v:
Immunology Letters. 42:91-95
The functional activity of Fc gamma RIII on human K cells from peripheral blood was compared with that of Fc gamma RIII on peritoneal macrophages (PM) separated from the waste material of patients undergoing peritoneal dialysis. Fc gamma R function w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fd7be199563e1605ba24db604ef29d
https://doi.org/10.1016/0165-2478(94)90041-8
https://doi.org/10.1016/0165-2478(94)90041-8
Autor:
Belinda M. Kumpel, Tibor Bakács
Publikováno v:
Immunology Letters. 31:237-240
Red cells were pretreated with the proteolytic enzymes bromelain or papain prior to use in antibody-dependent cell-mediated cytotoxicity (ADCC) assays with lymphocytes or peripheral blood mononuclear cells (PBMC) as effector cells. At low concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c924d3b2e015bf09762a052423b58f
https://doi.org/10.1016/0165-2478(92)90120-d
https://doi.org/10.1016/0165-2478(92)90120-d