Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Belinda K. Cornes"'
Autor:
Belinda K Cornes, Carolyn Paisie, Emily Swanzey, Peter D Fields, Andrew Schile, Kelly Brackett, Laura G Reinholdt, Anuj Srivastava
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 4 (2023)
AbstractOutbred laboratory mice (Mus musculus
Externí odkaz:
https://doaj.org/article/8f0a15df6c614837ab1610d8fee0ce93
Autor:
Monisha E Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K Cornes, Li-Jia Chen, Chunyan Qiao, K Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Do Tan, Khaled Abu-Amero, Shamira A Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A Tajudin, Ching-Lin Ho, Clement C Y Tham, Ileana Soto, Paul T K Chew, Hon-Tym Wong, Balekudaru Shantha, Masako Kuroda, Essam A Osman, Guangxian Tang, Sujie Fan, Hailin Meng, Hua Wang, Bo Feng, Victor H K Yong, Serena M L Ting, Yang Li, Ya-Xing Wang, Zheng Li, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Daniel H Su, Seng-Chee Loon, Vernon K Y Yong, R Rand Allingham, Michael A Hauser, Nagaswamy Soumittra, Vedam L Ramprasad, Naushin Waseem, Azhany Yaakub, Kee-Seng Chia, Govindasamy Kumaramanickavel, Tina T Wong, Alicia C How, Tran Nguyen Bich Chau, Cameron P Simmons, Jin-Xin Bei, Yi-Xin Zeng, Shomi S Bhattacharya, Mingzhi Zhang, Donald T Tan, Yik-Ying Teo, Saleh A Al-Obeidan, Do Nhu Hon, E-Shyong Tai, Seang-Mei Saw, Paul J Foster, Lingam Vijaya, Jost B Jonas, Tien-Yin Wong, Simon W M John, Chi-Pui Pang, Eranga N Vithana, Ningli Wang, Tin Aung
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004089 (2014)
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to discover novel genes for PACG on a total of 5,308 population-based individuals of As
Externí odkaz:
https://doaj.org/article/877cd4c646ac4df2b2fcf327072cf4be
Autor:
Elizabeth G Holliday, Albert V Smith, Belinda K Cornes, Gabriëlle H S Buitendijk, Richard A Jensen, Xueling Sim, Thor Aspelund, Tin Aung, Paul N Baird, Eric Boerwinkle, Ching Yu Cheng, Cornelia M van Duijn, Gudny Eiriksdottir, Vilmundur Gudnason, Tamara Harris, Alex W Hewitt, Michael Inouye, Fridbert Jonasson, Barbara E K Klein, Lenore Launer, Xiaohui Li, Gerald Liew, Thomas Lumley, Patrick McElduff, Barbara McKnight, Paul Mitchell, Bruce M Psaty, Elena Rochtchina, Jerome I Rotter, Rodney J Scott, Wanting Tay, Kent Taylor, Yik Ying Teo, André G Uitterlinden, Ananth Viswanathan, Sophia Xie, Wellcome Trust Case Control Consortium, Johannes R Vingerling, Caroline C W Klaver, E Shyong Tai, David Siscovick, Ronald Klein, Mary Frances Cotch, Tien Y Wong, John Attia, Jie Jin Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53830 (2013)
Genetic factors explain a majority of risk variance for age-related macular degeneration (AMD). While genome-wide association studies (GWAS) for late AMD implicate genes in complement, inflammatory and lipid pathways, the genetic architecture of earl
Externí odkaz:
https://doaj.org/article/a11730c6607349879dffa1cf36fe1d60
Autor:
Man-Ting So, Thomas Yuk-Yu Leon, Guo Cheng, Clara Sze-Man Tang, Xiao-Ping Miao, Belinda K Cornes, Ngoc Ngo Diem, Long Cui, Elly Sau-Wai Ngan, Vincent Chai-Hang Lui, Xuan-Zhao Wu, Bin Wang, Hualong Wang, Zheng-Wei Yuan, Liu-Ming Huang, Long Li, Huimin Xia, Deli Zhu, Juncheng Liu, Thanh Liem Nguyen, Ivy Hau-Yee Chan, Patrick Ho-Yu Chung, Xue-Lai Liu, Ruizhong Zhang, Kenneth Kak-Yuen Wong, Pak-Chung Sham, Stacey S Cherny, Paul Kwong-Hang Tam, Maria-Mercè Garcia-Barcelo
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28986 (2011)
Rare (RVs) and common variants of the RET gene contribute to Hirschsprung disease (HSCR; congenital aganglionosis). While RET common variants are strongly associated with the commonest manifestation of the disease (males; short-segment aganglionosis;
Externí odkaz:
https://doaj.org/article/2bc637cd25a94f7abcae0723d404adea
Autor:
Belinda K Cornes, Clara S Tang, Thomas Y Y Leon, Kenneth J W S Hui, Man-Ting So, Xiaoping Miao, Stacey S Cherny, Pak C Sham, Paul K H Tam, Maria-Merce Garcia-Barcelo
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10918 (2010)
BACKGROUND: Hirschsprung's disease (HSCR) is a congenital disorder associated with the lack of intramural ganglion cells in the myenteric and sub-mucosal plexuses along varying segments of the gastrointestinal tract. The RET gene is the major gene im
Externí odkaz:
https://doaj.org/article/fec126ddfa0647ed947b4419088bc61b
Autor:
Janine H Stubbe, Dorret I Boomsma, Jacqueline M Vink, Belinda K Cornes, Nicholas G Martin, Axel Skytthe, Kirsten O Kyvik, Richard J Rose, Urho M Kujala, Jaakko Kaprio, Jennifer R Harris, Nancy L Pedersen, Janice Hunkin, Tim D Spector, Eco J C de Geus
Publikováno v:
PLoS ONE, Vol 1, p e22 (2006)
A sedentary lifestyle remains a major threat to health in contemporary societies. To get more insight in the relative contribution of genetic and environmental influences on individual differences in exercise participation, twin samples from seven co
Externí odkaz:
https://doaj.org/article/1d6daa537a2442f999cf6438341e5f92
Autor:
Peter M Visscher, Sarah E Medland, Manuel A R Ferreira, Katherine I Morley, Gu Zhu, Belinda K Cornes, Grant W Montgomery, Nicholas G Martin
Publikováno v:
PLoS Genetics, Vol 2, Iss 3, p e41 (2006)
The study of continuously varying, quantitative traits is important in evolutionary biology, agriculture, and medicine. Variation in such traits is attributable to many, possibly interacting, genes whose expression may be sensitive to the environment
Externí odkaz:
https://doaj.org/article/207761f2d01f43af9acfc652c1c5491a
Autor:
Josée Dupuis, Belinda K. Cornes, Yuning Chen, Marco Dauriz, Aaron Isaacs, Sara M. Willems, Robert C. Kaplan, Donna M. Muzny, Ching-Ti Liu, Eric Boerwinkle, Bruce M. Psaty, Denis Rybin, David S. Siscovick, Cornelia M. van Duijn, Jerome I. Rotter, Leonard Lipovich, Jennifer A. Brody, Alanna C. Morrison, James B. Meigs, Richard A. Gibbs, Ramachandran S. Vasan, James S. Pankow
Publikováno v:
European Journal of Human Genetics, 24(9), 1337-1343. Nature Publishing Group
European journal of human genetics : EJHG, vol 24, iss 9
European journal of human genetics : EJHG, vol 24, iss 9
Insulin-like growth factor 1 (IGF-I) has been associated with insulin resistance. Genome-wide association studies (GWASs) of fasting insulin (FI) identified single-nucleotide variants (SNVs) near the IGF1 gene, raising two hypotheses: (1) these assoc
Autor:
Takanori Mizoguchi, Donald T.H. Tan, Renyi Wu, Hon-Tym Wong, Simon W. M. John, Shamira A. Perera, Michael A. Hauser, Tien Yin Wong, Azhany Yaakub, Yasuo Kurimoto, Jin-Xin Bei, Zheng Li, Eranga N. Vithana, Tina T. Wong, Mineo Ozaki, Serena M. L. Ting, Ningli Wang, Lingam Vijaya, Sancy Low, Chiea Chuen Khor, Ileana Soto, E-Shyong Tai, Hua Wang, Saleh A. Al-Obeidan, Hailin Meng, R. Rand Allingham, Govindasamy Kumaramanickavel, K. Saidas Nair, Ya Xing Wang, Kee Seng Chia, Daniel H. Su, Tran Nguyen Bich Chau, Seang-Mei Saw, Chunyan Qiao, Clement C Y Tham, Seng-Chee Loon, Victor H. K. Yong, Do Nhu Hon, Chi Pui Pang, Essam A. Osman, Shomi S. Bhattacharya, Paul T K Chew, Do Tan, Vedam L. Ramprasad, Ching-Lin Ho, Yik Ying Teo, Naushin Waseem, Liza-Sharmini Ahmad Tajudin, Cameron P. Simmons, Li Jia Chen, Hongyan Jia, Belinda K. Cornes, Alicia C. How, Monisha E. Nongpiur, Liang Xu, Khaled K. Abu-Amero, Bo Feng, Ronnie George, Yingfeng Zheng, Guangxian Tang, Jost B. Jonas, Ching-Yu Cheng, Yang Li, Nagaswamy Soumittra, Sujie Fan, Yi Xin Zeng, Mingzhi Zhang, Masako Kuroda, Balekudaru Shantha, Paul J. Foster, Tin Aung, Raghavan Lavanya
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004089 (2014)
PLoS Genetics
PLoS Genetics
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to discover novel genes for PACG on a total of 5,308 population-based individuals of As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10cb594c045fad4ca65ad405f94d718
https://ora.ox.ac.uk/objects/uuid:6facdebc-4c5e-4a75-ad14-fdb2f0f66aa5
https://ora.ox.ac.uk/objects/uuid:6facdebc-4c5e-4a75-ad14-fdb2f0f66aa5
Autor:
Belinda K. Cornes, Agata Smogorzewska, Stephen C. Kowalczykowski, Carrie Sougnez, Taeho Kim, Henrik Molina, Brooke A. Conti, Avinash Abhyankar, Francis P. Lach, Erica Sanborn, Athena L. Huang, Arleen D. Auerbach, Anderson T. Wang, Heather Zierhut, John E. Wagner, Stacey Gabriel
Publikováno v:
Molecular cell, vol 59, iss 3
Repair of DNA interstrand crosslinks requires action of multiple DNA repair pathways, including homologous recombination. Here, we report a de novo heterozygous T131P mutation in RAD51/FANCR, the key recombinase essential for homologous recombination