Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants

Autor: Jing Guo, Xiaoping Zhang, Aarti Saiganesh, Christopher Peacock, Shu Chen, Gary A. Dykes, Belinda J. Hales, Peter N. Le Souëf, Guicheng Zhang

Publikováno v: Allergy, Asthma & Clinical Immunology, Vol 16, Iss 1, Pp 1-10 (2020)

Abstract Background Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese immigrants, which fail

Externí odkaz: https://doaj.org/article/fa3fc4ef7a7d47f6bf87e0f2838efc15

Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

Autor: Yong Song, Hilda Higgins, Jing Guo, Katrina Harrison, En Nee Schultz, Belinda J. Hales, Eric K. Moses, Jack Goldblatt, Nicholas Pachter, Guicheng Zhang

Publikováno v: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)

Abstract Background Circulating microRNAs (miRNAs) are emerging as novel biomarkers for detecting cardiovascular diseases. In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congen

Externí odkaz: https://doaj.org/article/3e4238012997449db785136a8c62fdc7

Children with chronic suppurative lung disease have a reduced capacity to synthesize interferon-gamma in vitro in response to non-typeable Haemophilus influenzae.

Autor: Susan J Pizzutto, Stephanie T Yerkovich, John W Upham, Belinda J Hales, Wayne R Thomas, Anne B Chang

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e104236 (2014)

Chronic suppurative lung disease (CSLD) is characterized by the presence of a chronic wet or productive cough and recurrent lower respiratory infections. The aim of this study was to identify features of innate, cell-mediated and humoral immunity tha

Externí odkaz: https://doaj.org/article/45752a455c9546a5871f727136521208

Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants

Autor: Peter N. Le Souëf, Aarti Saiganesh, Shu Chen, Christopher S. Peacock, Gary A. Dykes, Guicheng Zhang, Xiaoping Zhang, Belinda J. Hales, Jing Guo

Publikováno v: Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Allergy, Asthma & Clinical Immunology, Vol 16, Iss 1, Pp 1-10 (2020)

Background Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese immigrants, which fails to prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5527fd9176e7685dc38694069df10f18
http://europepmc.org/articles/PMC7491349

Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

Autor: Wayne R. Thomas, Orathai Jirapongsananuruk, Surapon Piboonpocanun, Sasipa Thanyaratsrisakul, Belinda J. Hales, Bhakkawarat Kulwanich

Publikováno v: Allergy, Asthma & Immunology Research

Purpose Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been studied. This study aimed to determine the effect of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6074ad1ca116e4ba972fafad02713da3
http://europepmc.org/articles/PMC6267192