Výsledky vyhledávání - "Belinda C. Cupid"

Quantitative structure chromatography relationships in reversed-phase high performance liquid chromatography: Prediction of retention behaviour using theoretically derived molecular properties

Autor: C. R. Beddell, Jeremy K. Nicholson, John C. Lindon, Ian D. Wilson, V. S. Rose, R.J. Ruane, R. C. Glen, P. Davis, Belinda C. Cupid

Publikováno v: Chromatographia. 37:241-249

The use of theoretically calculated molecular properties as predictors for retention in reversed-phase HPLC has been explored. HPLC retention times have been measured for a series of 47 substituted aromatic molecules in three solvent mixtures and ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8990047b31d5553712a3a7cdb1d99a3d
https://doi.org/10.1007/bf02278628

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Detection of O6-carboxymethyl-2'-deoxyguanosine in DNA following reaction of nitric oxide with glycine and in human blood DNA using a quantitative immunoslot blot assay

Autor: Zuotao Zeng, David E. G. Shuker, Rajinder Singh, Belinda C. Cupid

Publikováno v: Chemical research in toxicology. 17(3)

Previous research has shown that a range of nitrosated glycine derivatives react with DNA to form O6-carboxymethylguanine and O6-methylguanine DNA adducts [Harrison et al. (1999) Chem. Res. Toxicol. 12, 106-111). Nitrosated glycine derivatives may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f66c58a6f690b7244c32468fdc54a
https://pubmed.ncbi.nlm.nih.gov/15025499

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Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7

Autor: Belinda C. Cupid, John C. Lindon, Jeremy K. Nicholson, R.Duncan Farrant

Publikováno v: Journal of pharmaceutical and biomedical analysis. 16(1)

The use of 2H NMR spectroscopy as a detector for HPLC has been investigated using the continuous flow method in which rat urine containing metabolites of N-dimethylformamide-d7 was employed as a test case. Three xenobiotic-related species, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff665010dee800731ee0e435dc70dcf9
https://pubmed.ncbi.nlm.nih.gov/9447545

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Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: application to N,N-dimethylformamide

Autor: R. Duncan Farrant, Salman R. Salman, John C. Lindon, Jeremy K. Nicholson, Belinda C. Cupid

Publikováno v: Journal of pharmaceutical and biomedical analysis. 11(8)

The metabolism of N,N-dimethylformamide in the Sprague-Dawley rat has been reinvestigated using NMR spectroscopy of urine. In particular, through the use of N,N-dimethylformamide-d7 (DMF-d7) and 2H-NMR spectroscopy, the principal metabolites of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d2b5eebc7e2bfcb653ec1a056e4c6d
https://pubmed.ncbi.nlm.nih.gov/8257732

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