Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Belinda Baquero-Pérez"'
Autor:
Belinda Baquero-Pérez, Ivaylo D. Yonchev, Anna Delgado-Tejedor, Rebeca Medina, Mireia Puig-Torrents, Ian Sudbery, Oguzhan Begik, Stuart A. Wilson, Eva Maria Novoa, Juana Díez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Despite the nuclear localization of the m6A machinery, the genomes of multiple exclusively-cytoplasmic RNA viruses, such as chikungunya (CHIKV) and dengue (DENV), are reported to be extensively m6A-modified. However, these findings are mostl
Externí odkaz:
https://doaj.org/article/904df08738cd42fd9380f06809a3d04d
Autor:
Belinda Baquero-Pérez, Enrico Bortoletto, Umberto Rosani, Anna Delgado-Tejedor, Rebeca Medina, Eva Maria Novoa, Paola Venier, Juana Díez
Publikováno v:
Viruses, Vol 16, Iss 6, p 945 (2024)
The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of v
Externí odkaz:
https://doaj.org/article/c553345565e242e7b17d65bf7600f68e
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005274 (2015)
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic herpesvirus associated with various AIDS-related malignancies. Like other herpesviruses, multiple processes required for KSHV lytic replication, including viral transcription, viral DNA s
Externí odkaz:
https://doaj.org/article/2b28b4c62f0c470cb3692bc211faf4f6
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004771 (2015)
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients. For many non-viral malignancies, therape
Externí odkaz:
https://doaj.org/article/7103d46cbca24aefb2f4dcc3fe649980
Autor:
David J, Hughes, Jennifer J, Wood, Brian R, Jackson, Belinda, Baquero-Pérez, Adrian, Whitehouse
Publikováno v:
PLoS Pathogens
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients. For many non-viral malignancies, thera
Autor:
Oliver Manners, Belinda Baquero-Perez, Timothy J. Mottram, Ivaylo D. Yonchev, Christopher J. Trevelyan, Katherine L. Harper, Sarah Menezes, Molly R. Patterson, Andrew Macdonald, Stuart A. Wilson, Julie L. Aspden, Adrian Whitehouse
Publikováno v:
Viruses, Vol 15, Iss 6, p 1381 (2023)
The epitranscriptomic modification N6-methyladenosine (m6A) is a ubiquitous feature of the mammalian transcriptome. It modulates mRNA fate and dynamics to exert regulatory control over numerous cellular processes and disease pathways, including viral
Externí odkaz:
https://doaj.org/article/b19ae048890c4828ba676b2dcde8e195
Publikováno v:
Viruses, Vol 13, Iss 6, p 1049 (2021)
There are over 100 different chemical RNA modifications, collectively known as the epitranscriptome. N6-methyladenosine (m6A) is the most commonly found internal RNA modification in cellular mRNAs where it plays important roles in the regulation of t
Externí odkaz:
https://doaj.org/article/889d80eb1f914a1788efc3ea961a0c6a
Autor:
Belinda Baquero-Perez, Agne Antanaviciute, Ivaylo D Yonchev, Ian M Carr, Stuart A Wilson, Adrian Whitehouse
Publikováno v:
eLife, Vol 8 (2019)
N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation. Using an m6A-modif
Externí odkaz:
https://doaj.org/article/8f45fcf9731d40a1852c8fa1a6403483
Publikováno v:
Viruses, Vol 5, Iss 8, Pp 1901-1923 (2013)
Nuclear mRNA export is a highly complex and regulated process in cells. Cellular transcripts must undergo successful maturation processes, including splicing, 5'-, and 3'-end processing, which are essential for assembly of an export competent ribonuc
Externí odkaz:
https://doaj.org/article/a67895c9f27d453eba90613b0215c834