WNT4 overexpression and secretion in thymic epithelial tumors drive an autocrine loop in tumor cells in vitro .

Autor: Zhang X; Institute of Pathology and Medical Research Center, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Schalke B; Department of Neurology, University of Regensburg, Regensburg, Germany., Kvell K; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Pecs, Pecs, Hungary., Kriegsmann K; Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany., Kriegsmann M; Translational Lung Research Centre Heidelberg, German Centre for Lung Research, Heidelberg, Germany.; Institute of Pathology, University Hospital Heidelberg, Heidelberg University, Heidelberg, Germany., Graeter T; Department of Thoracic Surgery, University Medical Centre Erlangen, Erlangen, Germany., Preissler G; Department of Thoraxic Surgery, Clinic Schillerhöhe, Robert-Bosch-Hospital, Gerlingen, Löwenstein, Germany., Ott G; Department of Clinical Pathology, Robert-Bosch-Hospital, Stuttgart, Germany.; Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Robert-Bosch-Hospital, Stuttgart, Germany., Kurz K; Department of Clinical Pathology, Robert-Bosch-Hospital, Stuttgart, Germany.; Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Robert-Bosch-Hospital, Stuttgart, Germany., Bulut E; Department of Thoraxic Surgery, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany., Ströbel P; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany., Marx A; Institute of Pathology and Medical Research Center, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Belharazem D; Institute of Pathology and Medical Research Center, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.

Publikováno v: Frontiers in oncology [Front Oncol] 2022 Jul 29; Vol. 12, pp. 920871. Date of Electronic Publication: 2022 Jul 29 (Print Publication: 2022).

Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets.

Autor: Alwahsh M; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., 44139 Dortmund, Germany.; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany.; Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan., Knitsch R; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., 44139 Dortmund, Germany., Marchan R; Department of Toxicology, Leibniz Research Center for Working Environment and Human Factors at the TU Dortmund (IfADo), 44139 Dortmund, Germany., Lambert J; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., 44139 Dortmund, Germany., Hoerner C; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany., Zhang X; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany., Schalke B; Department of Neurology, University of Regensburg, 93053 Regensburg, Germany., Lee DH; Department of Neurology, University of Regensburg, 93053 Regensburg, Germany., Bulut E; Department of Thoracic Surgery, Thoraxklinik at Heidelberg University Hospital, 69120 Heidelberg, Germany., Graeter T; Thoracic Surgery, Clinic Löwenstein, 74245 Löwenstein, Germany., Ott G; Department of Clinical Pathology, Robert-Bosch-Krankenhaus and Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, 70376 Stuttgart, Germany., Kurz KS; Department of Clinical Pathology, Robert-Bosch-Krankenhaus and Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, 70376 Stuttgart, Germany., Preissler G; Department of Thoracic Surgery, RBK Lungenzentrum Stuttgart, Robert Bosch Hospital, Clinic Schillerhoehe, 70839 Gerlingen, Germany.; DZL, German Center for Lung Research (Deutsches Zentrum fuer Lungenforschung), Department of Thoracic Surgery, Ludwig-Maximilians University Munich, 81377 Munich, Germany., Schölch S; JCCU Translational Surgical Oncology (A430), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; DKFZ-Hector Cancer Institute at University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany.; Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Farhat J; Department of Pharmacy, Faculty of Pharmacy, Al Ain University, Abu Dhabi P.O. Box 122612, United Arab Emirates., Yao Z; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany., Sticht C; NGS Core Facility, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Ströbel P; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, 37075 Göttingen, Germany., Hergenröder R; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., 44139 Dortmund, Germany., Marx A; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany., Belharazem D; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2022 Mar 18; Vol. 14 (6). Date of Electronic Publication: 2022 Mar 18.

Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas.

Autor: Müller D; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany., Mazzeo P; Department of Haematology and Medical Oncology, University Medical Centre Göttingen, Göttingen, Germany., Koch R; Department of Haematology and Medical Oncology, University Medical Centre Göttingen, Göttingen, Germany., Bösherz MS; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany., Welter S; Thoracic Surgery Department, Lung Clinic Hemer, Hemer, Germany., von Hammerstein-Equord A; Department of Heart, Thoracic and Vascular Surgery, University Medical Center Göttingen, Göttingen, Germany., Hinterthaner M; Department of Thoracic and Cardiovascular Surgery, University Medical Center, Göttingen, Germany., Cordes L; Thoracic Surgery Department, Lung Clinic Hemer, Hemer, Germany., Belharazem D; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Marx A; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Ströbel P; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany. philipp.stroebel@med.uni-goettingen.de., Küffer S; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

Publikováno v: BMC medicine [BMC Med] 2021 Nov 16; Vol. 19 (1), pp. 300. Date of Electronic Publication: 2021 Nov 16.

Molecular pathology of thymomas: implications for diagnosis and therapy.

Autor: Marx A; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. alexander.marx@umm.de., Belharazem D; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany., Lee DH; Department of Neurology, University of Regensburg, Regensburg, Germany., Popovic ZV; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany., Reißfelder C; Department of Surgery, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schalke B; Department of Neurology, University of Regensburg, Regensburg, Germany., Schölch S; Department of Surgery, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Junior Clinical Cooperation Unit Translational Surgical Oncology (A430), German Cancer Research Center (DKFZ), Heidelberg, Germany., Ströbel P; Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany., Weis CA; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany., Yamada Y; Institute of Pathology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.; Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.

Publikováno v: Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Jan; Vol. 478 (1), pp. 101-110. Date of Electronic Publication: 2021 Mar 05.

FOSL1-mediated LINC01566 negatively regulates CD4⁺ T-cell activation in myasthenia gravis.

Autor: Li, Lifang¹ (AUTHOR), Li, Danyang¹ (AUTHOR), Jin, Jingnan¹ (AUTHOR), Xu, Fanfan¹ (AUTHOR), He, Ni¹ (AUTHOR), Ren, Yingjie¹ (AUTHOR), Wang, Xiaokun¹ (AUTHOR), Tian, Liting¹ (AUTHOR), Chen, Biying¹ (AUTHOR), Li, Xiaoju¹ (AUTHOR), Chen, Zihong¹ (AUTHOR), Zhang, Lanxin¹ (AUTHOR), Qiao, Lukuan¹ (AUTHOR), Wang, Lihua¹ (AUTHOR) wanglh211@163.com, Wang, Jianjian¹ (AUTHOR) wangjian_427@163.com

Publikováno v: Journal of Neuroinflammation. 8/7/2024, Vol. 21 Issue 1, p1-17. 17p.