The Potential of Usnic-Acid-Based Thiazolo-Thiophenes as Inhibitors of the Main Protease of SARS-CoV-2 Viruses.

Autor: Yarovaya OI; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Filimonov AS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Baev DS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; Synchrotron Radiation Facility SKIF, G.K. Boreskov Institute of Catalysis SB RAS, 630559 Koltsovo, Russia., Borisevich SS; Synchrotron Radiation Facility SKIF, G.K. Boreskov Institute of Catalysis SB RAS, 630559 Koltsovo, Russia.; Laboratory of Chemical Physics, Ufa Institute of Chemistry, Ufa Federal Research Centre, 450078 Ufa, Russia., Zaykovskaya AV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Chirkova VY; Institute of Biology and Biotechnology, Altay State University, 656049 Barnaul, Russia., Marenina MK; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Meshkova YV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Belenkaya SV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Shcherbakov DN; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.; Institute of Biology and Biotechnology, Altay State University, 656049 Barnaul, Russia., Gureev MA; Laboratory of Bio- and Cheminformatics, St. Petersburg School of Physics, Mathematics and Computer Science, HSE University, 194100 St. Peterburg, Russia., Luzina OA; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Salakhutdinov NF; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Khvostov MV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.

Publikováno v: Viruses [Viruses] 2024 Jan 31; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 31.

Biochemical Properties of a Promising Milk-Clotting Enzyme, Moose ( Alces alces ) Recombinant Chymosin.

Autor: Balabova DV; Institute of Biology and Biotechnology, Altai State University, 656049 Barnaul, Russia., Belash EA; Institute of Biology and Biotechnology, Altai State University, 656049 Barnaul, Russia., Belenkaya SV; State Research Center for Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Shcherbakov DN; Institute of Biology and Biotechnology, Altai State University, 656049 Barnaul, Russia.; State Research Center for Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Belov AN; Federal Altai Scientific Center for Agrobiotechnologies, Siberian Research Institute of Cheese Making, 656910 Barnaul, Russia., Koval AD; Federal Altai Scientific Center for Agrobiotechnologies, Siberian Research Institute of Cheese Making, 656910 Barnaul, Russia., Mironova AV; Federal Altai Scientific Center for Agrobiotechnologies, Siberian Research Institute of Cheese Making, 656910 Barnaul, Russia., Bondar AA; JCF 'Genomics', Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Volosnikova EA; State Research Center for Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Arkhipov SG; Boreskov Institute of Catalysis, Siberan Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Sokolova OO; Boreskov Institute of Catalysis, Siberan Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Chirkova VY; Institute of Biology and Biotechnology, Altai State University, 656049 Barnaul, Russia., Elchaninov VV; Federal Altai Scientific Center for Agrobiotechnologies, Siberian Research Institute of Cheese Making, 656910 Barnaul, Russia.

Publikováno v: Foods (Basel, Switzerland) [Foods] 2023 Oct 13; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 13.

The effect of thioredoxin and prochymosin coexpression on the refolding of recombinant alpaca chymosin.

Autor: Belenkaya SV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, Koltsovo, Novosibirsk region, Russia Altai State University, Barnaul, Russia., Shcherbakov DN; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, Koltsovo, Novosibirsk region, Russia Altai State University, Barnaul, Russia., Chapoval AI; Altai State University, Barnaul, Russia., Esina TI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, Koltsovo, Novosibirsk region, Russia., Elchaninov VV; Federal Altai Scientific Center for Agrobiotechnology, Siberian Research Institute of Cheesemaking, Barnaul, Russia.

Publikováno v: Vavilovskii zhurnal genetiki i selektsii [Vavilovskii Zhurnal Genet Selektsii] 2023 Jul; Vol. 27 (4), pp. 421-427.

The Search for Single-Domain Antibodies Interacting with the Receptor-Binding Domain of SARS-CoV-2 Surface Protein.

Autor: Aripov VS; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia. aripov_vs@vector.nsc.ru., Volkova NV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Taranin AV; Institute of Molecular and Cellular Biology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia., Mechetina LV; Institute of Molecular and Cellular Biology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia., Chikaev NA; Institute of Molecular and Cellular Biology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia., Nayakshin AM; Institute of Molecular and Cellular Biology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia., Nesmeyanova VS; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Isaeva AA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Merkul'eva YA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Shanshin DV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Belenkaya SV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Ilyichev AA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia., Shcherbakov DN; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Koltsovo, Novosibirsk region, Russia.

Publikováno v: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2023 Jun; Vol. 175 (2), pp. 225-228. Date of Electronic Publication: 2023 Jul 19.

Synthesis of conjugates of (a R ,7 S )-colchicine with monoterpenoids and investigation of their biological activity.

Autor: Shchegravina ES; Lobachevsky State University of Nizhny Novgorod, k. 2, 23 prosp. Gagarina, 603950 Nizhny Novgorod, Russian Federation., Usova SD; Lobachevsky State University of Nizhny Novgorod, k. 2, 23 prosp. Gagarina, 603950 Nizhny Novgorod, Russian Federation., Baev DS; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. Akad. Lavrent'eva, 630090 Novosibirsk, Russian Federation., Mozhaitsev ES; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. Akad. Lavrent'eva, 630090 Novosibirsk, Russian Federation., Shcherbakov DN; State Scientific Center of Virology and Biotechnology 'Vector', 630559 Koltsovo, Novosibirsk Region, Russian Federation., Belenkaya SV; State Scientific Center of Virology and Biotechnology 'Vector', 630559 Koltsovo, Novosibirsk Region, Russian Federation.; Novosibirsk State University, 1 ul. Pirogova, 630090 Novosibirsk, Russian Federation., Volosnikova EA; State Scientific Center of Virology and Biotechnology 'Vector', 630559 Koltsovo, Novosibirsk Region, Russian Federation., Chirkova VY; Altai State University, 61 Leninsky prosp., 656049 Barnaul, Russian Federation., Sharlaeva EA; Altai State University, 61 Leninsky prosp., 656049 Barnaul, Russian Federation., Svirshchevskaya EV; Department of Immunology, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 ul. Miklukho-Maklaya, 117997 Moscow, Russian Federation., Fonareva IP; Lobachevsky State University of Nizhny Novgorod, k. 2, 23 prosp. Gagarina, 603950 Nizhny Novgorod, Russian Federation., Sitdikova AR; Lobachevsky State University of Nizhny Novgorod, k. 2, 23 prosp. Gagarina, 603950 Nizhny Novgorod, Russian Federation., Salakhutdinov NF; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. Akad. Lavrent'eva, 630090 Novosibirsk, Russian Federation., Yarovaya OI; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. Akad. Lavrent'eva, 630090 Novosibirsk, Russian Federation., Fedorov AY; Lobachevsky State University of Nizhny Novgorod, k. 2, 23 prosp. Gagarina, 603950 Nizhny Novgorod, Russian Federation.

Publikováno v: Russian chemical bulletin = Izvestiia Akademii nauk. Seriia khimicheskaia [Russ Chem Bull] 2023; Vol. 72 (1), pp. 248-262. Date of Electronic Publication: 2023 Feb 14.