Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Belen, Palencia"'
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTPrevious studies have shown that local delivery of tumor antigen-specific CD8+ T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious. Peritoneal dissemination of cancer is a frequent and often fatal pat
Externí odkaz:
https://doaj.org/article/7995ddacfe9f449ca1ff8dccf0f9a256
Autor:
Assunta Cirella, Elixabet Bolaños, Claudia Augusta Di Trani, Carlos E. de Andrea, Sandra Sánchez-Gregorio, Iñaki Etxeberria, Jose Gonzalez-Gomariz, Irene Olivera, Davide Brocco, Javier Glez-Vaz, Carlos Luri-Rey, Arantza Azpilikueta, Inmaculada Rodríguez, Myriam Fernandez-Sendín, Josune Egea, Iñaki Eguren, Miguel F. Sanmamed, Belen Palencia, Alvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Cancer Immunology Research. 11:184-198
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding IL12 and IL18. M
Autor:
Ignacio Melero, Pedro Berraondo, Alvaro Teijeira, Belen Palencia, Miguel F. Sanmamed, Iñaki Eguren, Josune Egea, Myriam Fernandez-Sendín, Inmaculada Rodríguez, Arantza Azpilikueta, Carlos Luri-Rey, Javier Glez-Vaz, Davide Brocco, Irene Olivera, Jose Gonzalez-Gomariz, Iñaki Etxeberria, Sandra Sánchez-Gregorio, Carlos E. de Andrea, Claudia Augusta Di Trani, Elixabet Bolaños, Assunta Cirella
Supplementary figures 1-8 and supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55de1d63f2018b5b1f25ddd31b7fe707
https://doi.org/10.1158/2326-6066.22546073
https://doi.org/10.1158/2326-6066.22546073
Autor:
Ignacio Melero, Pedro Berraondo, Alvaro Teijeira, Belen Palencia, Miguel F. Sanmamed, Iñaki Eguren, Josune Egea, Myriam Fernandez-Sendín, Inmaculada Rodríguez, Arantza Azpilikueta, Carlos Luri-Rey, Javier Glez-Vaz, Davide Brocco, Irene Olivera, Jose Gonzalez-Gomariz, Iñaki Etxeberria, Sandra Sánchez-Gregorio, Carlos E. de Andrea, Claudia Augusta Di Trani, Elixabet Bolaños, Assunta Cirella
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding IL12 and IL18. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437f9c251748ad1ccee76718bd3f677d
https://doi.org/10.1158/2326-6066.c.6551084
https://doi.org/10.1158/2326-6066.c.6551084
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology. 12
Autor:
Assunta, Cirella, Elixabet, Bolanos, Claudia Augusta, Di Trani, Carlos E, de Andrea, Sandra, Sánchez-Gregorio, Iñaki, Etxeberria, Jose, Gonzalez-Gomariz, Irene, Olivera, Davide, Brocco, Javier, Glez-Vaz, Carlos, Luri-Rey, Arantza, Azpilikueta, Inmaculada, Rodriguez, Myriam, Fernandez-Sendin, Josune, Egea, Iñaki, Eguren, Miguel F, Sanmamed, Belen, Palencia, Alvaro, Teijeira, Pedro, Berraondo, Ignacio, Melero
Publikováno v:
Cancer immunology research.
Interleukin-12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding interle
Autor:
Assunta Cirella, Carlos Luri-Rey, Claudia Augusta Di Trani, Alvaro Teijeira, Irene Olivera, Elixabet Bolaños, Eduardo Castañón, Belen Palencia, Davide Brocco, Myriam Fernández-Sendin, Fernando Aranda, Pedro Berraondo, Ignacio Melero
Publikováno v:
Pharmacology & Therapeutics
Interleukin-12 is considered a potent agent to enhance antitumor immune responses. It belongs to a family of heterodimeric cytokines with key roles in the up-regulation and down-regulation of cellular immunity. Since its discovery, recombinant IL-12
Autor:
Carlos Alfaro, Ignacio Melero, Natalia Suarez, Sandra Hervas-Stubbs, Asis Palazon, Aizea Morales, Juan Dubrot, Belen Palencia, Carmen Ochoa, Ivan Martinez Forero
Publikováno v:
Scopus-Elsevier
Division of labour among cells of the immune system is a prevailing theme in the orchestration of immune responses. Contrary to this paradigm, a particular leukocyte population in the mouse seems to be equipped with the ability to kill transformed an
Autor:
Eduardo Huarte, Ignacio Melero, Guillermo Mazzolini, Maria Vera, Oihana Murillo, Verónica Marín, Ainhoa Arina, Belen Palencia, Victoria Busto, Carlos Alfaro, Iñigo Tirapu
Publikováno v:
Expert Opinion on Biological Therapy. 5:7-22
Like paratroopers in special operations, dendritic cells (DCs) can be deployed behind the enemy borders of malignant tissue to ignite an antitumour immune response. 'Cross-priming T cell responses' is the code name for their mission, which consists o
Autor:
Arantza Azpilikueta, Belen Palencia, Sandra Hervas-Stubbs, Oihana Murillo, Jose Luis Perez-Gracia, Carlos Alfaro, Juan Dubrot, Maurizio Bendandi, Ignacio Melero, Ainhoa Arina
Publikováno v:
Expert opinion on biological therapy. 7(5)
There is compelling evidence for the role of natural killer (NK) cells in tumor immunosurveillance and their beneficial effects on many experimentally successful immunotherapy strategies. NK cells mediate cell contact-dependent cellular cytotoxicity