Zobrazeno 1 - 10
of 655
pro vyhledávání: '"Belayew, A."'
Autor:
Thuy-Hang Nguyen, Lise Paprzycki, Alexandre Legrand, Anne-Emilie Declèves, Philipp Heher, Maelle Limpens, Alexandra Belayew, Christopher R. S. Banerji, Peter S. Zammit, Alexandra Tassin
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Hypoxia is known to modify skeletal muscle biological functions and muscle regeneration. However, the mechanisms underlying the effects of hypoxia on human myoblast differentiation remain unclear. The hypoxic response pathway is o
Externí odkaz:
https://doaj.org/article/54f7e8b9df5a4c7f8986eef5f8194eb0
Autor:
Clothilde Claus, Moriya Slavin, Eugénie Ansseau, Céline Lancelot, Karimatou Bah, Saskia Lassche, Manon Fiévet, Anna Greco, Sara Tomaiuolo, Alexandra Tassin, Virginie Dudome, Benno Kusters, Anne-Emilie Declèves, Dalila Laoudj-Chenivesse, Baziel G. M. van Engelen, Denis Nonclercq, Alexandra Belayew, Nir Kalisman, Frédérique Coppée
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-30 (2023)
Abstract Background We have previously demonstrated that double homeobox 4 centromeric (DUX4C) encoded for a functional DUX4c protein upregulated in dystrophic skeletal muscles. Based on gain- and loss-of-function studies we have proposed DUX4c invol
Externí odkaz:
https://doaj.org/article/b5d8d28f164f438eaa5c5e0fc91b58bf
Autor:
Thuy-Hang Nguyen, Maelle Limpens, Sihame Bouhmidi, Lise Paprzycki, Alexandre Legrand, Anne-Emilie Declèves, Philipp Heher, Alexandra Belayew, Christopher R. S. Banerji, Peter S. Zammit, Alexandra Tassin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3327 (2024)
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent inherited muscle disorders and is linked to the inappropriate expression of the DUX4 transcription factor in skeletal muscles. The deregulated molecular network causing FSHD m
Externí odkaz:
https://doaj.org/article/f38a0076c826444eb8ce8da70e5120a5
Akademický článek
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Akademický článek
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Autor:
Aline Derenne, Alexandra Tassin, Thuy Hang Nguyen, Estelle De Roeck, Vincianne Jenart, Eugénie Ansseau, Alexandra Belayew, Frédérique Coppée, Anne-Emilie Declèves, Alexandre Legrand
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector injection for transgene expression into skeletal muscles. In this study, IMEP was used to express the DUX4 gene in
Externí odkaz:
https://doaj.org/article/de019a5459f549d595a0412b6acbd90b
Autor:
Alexandra Baroni, Ioan Neaga, Nicolas Delbosc, Mathilde Wells, Laetitia Verdy, Eugénie Ansseau, Jean Jacques Vanden Eynde, Alexandra Belayew, Ede Bodoki, Radu Oprean, Stéphanie Hambye, Bertrand Blankert
Publikováno v:
ACS Omega, Vol 4, Iss 19, Pp 18126-18135 (2019)
Externí odkaz:
https://doaj.org/article/3d9c9b6189f84170881715403bba9729
Autor:
Ludovic Dhont, Melania Pintilie, Ethan Kaufman, Roya Navab, Shirley Tam, Arsène Burny, Frances Shepherd, Alexandra Belayew, Ming-Sound Tsao, Céline Mascaux
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The relapse rate in early stage non-small cell lung cancer (NSCLC) after surgical resection is high. Prognostic biomarkers may help identify patients who may benefit from additional therapy. The Helicase-like Transcription Factor
Externí odkaz:
https://doaj.org/article/4f020d969dcb457fa8b79410046a1550
Autor:
Céline Vanderplanck, Alexandra Tassin, Eugénie Ansseau, Sébastien Charron, Armelle Wauters, Céline Lancelot, Kelly Vancutsem, Dalila Laoudj-Chenivesse, Alexandra Belayew, Frédérique Coppée
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is associated with DNA hypomethylation at the 4q35 D4Z4 repeat array. Both the causal gene DUX4 and its homolog DUX4c are induced. DUX4c is immunodetected in every myonucleus of prolif
Externí odkaz:
https://doaj.org/article/485299feb7c4452d954ba4108430e17d
Autor:
Thuy-Hang Nguyen, Stephanie Conotte, Alexandra Belayew, Anne-Emilie Declèves, Alexandre Legrand, Alexandra Tassin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7220 (2021)
Muscular dystrophies (MDs) are a group of inherited degenerative muscle disorders characterized by a progressive skeletal muscle wasting. Respiratory impairments and subsequent hypoxemia are encountered in a significant subgroup of patients in almost
Externí odkaz:
https://doaj.org/article/874bf5fe4e294074b4937175eb254499