Observation of preQ 1 -II riboswitch dynamics using single-molecule FRET.

Autor: Warnasooriya C; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA., Ling C; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA., Belashov IA; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA., Salim M; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA., Wedekind JE; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA., Ermolenko DN; a Department of Biochemistry & Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester , Rochester , NY , USA.

Publikováno v: RNA biology [RNA Biol] 2019 Sep; Vol. 16 (9), pp. 1086-1092. Date of Electronic Publication: 2018 Oct 30.

Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.

Autor: Belashov IA; Department of Biochemistry & Biophysics, Center for RNA Biology, and Center for AIDS Research, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA., Crawford DW; Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA., Cavender CE; Department of Biochemistry & Biophysics, Center for RNA Biology, and Center for AIDS Research, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA., Dai P; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Beardslee PC; Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA., Mathews DH; Department of Biochemistry & Biophysics, Center for RNA Biology, and Center for AIDS Research, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA., Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02139, USA., McNaughton BR; Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.; Department of Biochemistry & Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA., Wedekind JE; Department of Biochemistry & Biophysics, Center for RNA Biology, and Center for AIDS Research, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2018 Jul 27; Vol. 46 (13), pp. 6401-6415.

Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics.

Autor: Liberman JA; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;, Suddala KC; Single Molecule Analysis Group, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109; Biophysics, University of Michigan, Ann Arbor, MI 48109;, Aytenfisu A; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;, Chan D; Department of Pharmaceutical Sciences, University of California, Irvine, CA 92697., Belashov IA; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;, Salim M; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;, Mathews DH; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642;, Spitale RC; Department of Pharmaceutical Sciences, University of California, Irvine, CA 92697., Walter NG; Single Molecule Analysis Group, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109;, Wedekind JE; Department of Biochemistry and Biophysics, and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; joseph.wedekind@rochester.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Jul 07; Vol. 112 (27), pp. E3485-94. Date of Electronic Publication: 2015 Jun 23.