Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bela Joos"'
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196508 (2018)
Regulating membrane potential and synaptic function contributes significantly to the energetic costs of brain signaling, but the relative costs of action potentials (APs) and synaptic transmission during high-frequency firing are unknown. The continu
Externí odkaz:
https://doaj.org/article/d2947be0b1ee43cd812283657404c7d1
Publikováno v:
Biophysical Journal. 122:541a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e1a278b39d6cc585b648fc2fc7d51fa
https://doi.org/10.1016/j.bpj.2022.11.2866
https://doi.org/10.1016/j.bpj.2022.11.2866
Publikováno v:
Biophysical Journal. 121:123a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c5eafdb810bf22465226e7bd0d7863
https://doi.org/10.1016/j.bpj.2021.11.2098
https://doi.org/10.1016/j.bpj.2021.11.2098
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 3, p e1011846 (2024)
In a variety of neurons, action potentials (APs) initiate at the proximal axon, within a region called the axon initial segment (AIS), which has a high density of voltage-gated sodium channels (NaVs) on its membrane. In pyramidal neurons, the proxima
Externí odkaz:
https://doaj.org/article/9ca7ae03fdf34887b0f508682fde5c79
Publikováno v:
Handbook of experimental pharmacology. 246
Two features common to diverse sick excitable cells are "leaky" Nav channels and bleb damage-damaged membranes. The bleb damage, we have argued, causes a channel kinetics based "leakiness." Recombinant (node of Ranvier type) Nav1.6 channels voltage-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4868f68342a417ee54237ab1035cdfcf
https://pubmed.ncbi.nlm.nih.gov/29030712
https://pubmed.ncbi.nlm.nih.gov/29030712
Publikováno v:
AIP Advances, Vol 7, Iss 12, Pp 125003-125003-14 (2017)
We examine the effects of the external force, torque, temperature, confinement, and excluded volume interactions (EVIs) on the stability of the helical configuration of an intrinsically straight semiflexible biopolymer inside a cylindrical cell. We f
Externí odkaz:
https://doaj.org/article/84b4243099744d8cbfeed4ebe8fb88c4
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118335 (2015)
K-selective voltage-gated channels (Kv) are multi-conformation bilayer-embedded proteins whose mechanosensitive (MS) Popen(V) implies that at least one conformational transition requires the restructuring of the channel-bilayer interface. Unlike Morr
Externí odkaz:
https://doaj.org/article/c44e7006b1ec44a2bd763463f9ba267f
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 9, p e1002664 (2012)
In injured neurons, "leaky" voltage-gated sodium channels (Nav) underlie dysfunctional excitability that ranges from spontaneous subthreshold oscillations (STO), to ectopic (sometimes paroxysmal) excitation, to depolarizing block. In recombinant syst
Externí odkaz:
https://doaj.org/article/9ebd75f30c684234b25d9b14f3256cd8
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