Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bela A. Mehta"'
Autor:
Christine F. Hoyle, Charles D. Bangs, Pearl Chang, Onsi W. Kamel, Bela A. Mehta, Robert S. Negrin
Publikováno v:
Blood. 92:3318-3327
We have developed culture conditions for the efficient expansion of cytotoxic effector cells from peripheral blood mononuclear cells (PBMNCs) by the timed addition of interferon-γ (IFN-γ), interleukin-2 (IL-2), and the monoclonal antibody (MoAb) OK
Autor:
Petja Lefterova, Bela A. Mehta, Robert S. Negrin, Markus Csipai, Ingo G.H. Schmidt-Wolf, Dieter Huhn, Valerie Johnston, Takashi Tsuruo, Christian Scheffold
Publikováno v:
Cellular Immunology. 169:85-90
The ability of malignant cells to survive exposure to cytotoxic agents is a major obstacle to cure in patients with cancer. Multidrug resistance and the expression of P-glycoprotein are emerging as a cause of chemotherapy failure. Immunologic effecto
Publikováno v:
Blood. 86:3493-3499
Cytokine-induced killer (CIK) cells are non-major histocompatibility complex-restricted cytotoxic cells generated by incubation of peripheral blood lymphocytes with anti-CD3 monoclonal antibody (MoAb), interleukin-2 (IL-2), IL-1, and interferon-gamma
Publikováno v:
Cellular Immunology. 155:95-110
We evaluated LAK cell cytotoxicity toward a sensitive B cell lymphoma and several resistant EBV-transformed cell lines in order to explore the mechanism by which some cells are preferentially recognized as targets. Cytolysis of the sensitive cells wa
Autor:
Bela A Mehta, Vernon C. Maino
Publikováno v:
Journal of immunological methods. 208(1)
Assessment of T cell activation has traditionally been performed by measuring proliferation as a function of 3[H]-thymidine incorporation, or secretion of cytokines from activated peripheral blood mononuclear cells (PBMC) in culture. An alternative m
In vitro modulation of natural killer cell activity in non-Hodgkin's lymphoma patients after therapy
Publikováno v:
Cancer immunology, immunotherapy : CII. 28(2)
The depressed natural killer (NK) activity, anti-body-dependent cellular cytotoxicity (ADCC) and NK cytotoxic factor cytotoxicity in untreated non-Hodgkin's lymphoma patients were found to be elevated after chemotherapy. In vitro treatment of the eff
Publikováno v:
Oncology. 46(5)
Non-Hodgkin's lymphoma (NHL) patients classified according to the Rappaport classification system had depressed natural killer (NK) and NK cytotoxic factor activities, antibody-dependent cellular cytotoxicity, active killing potential as well as recy