Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bela, Desai"'
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
Clinical & experimental pharmacology
article-version (status) pre
article-version (number) 1
Clinical & experimental pharmacology
The impact of COVID-19 disease on health and economy has been global, and the magnitude of devastation is unparalleled in modern history. Any potential course of action to manage this complex disease requires the systematic and efficient analysis of
Autor:
Gulesi Ayanoglu, Erin Murphy, Scott P. Turner, Amy M Beebe, Ivan H. Chan, John B. Mumm, Venkataraman Sriram, Xueqing Zhang, Catherine Sheppard, Jeff Grein, Beth Basham, Martin Oft, Satya Medicherla, Jan Emmerich, Melanie A. Kleinschek, Lingling Wu, Michael Judo, Steven J. Blaisdell, Terrill K. McClanahan, Susan Cannon-Carlson, John L. Langowski, Danling Gu, Kyu Hong, Wolfgang Seghezzi, Smita Mauze, Brittany C. Paporello, Bela Desai, Saraswathi Naravula, Jie Dai, Drake LaFace, Collette M. Cutler
Publikováno v:
Cancer Cell. 20(6):781-796
Summary Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8 + T cells. Intratumoral CD8 + T cells are rare and lack activity. IL-10 is thought to contribute to the underlying im
Autor:
Mandy J. McGeachy, Bela Desai, Robert H. Pierce, Katia Boniface, Svetlana Sadekova, Terrill K. McClanahan, Katherine Brovont-Porth, Beth Basham, Rene de Waal Malefyt, Wendy M. Blumenschein
Publikováno v:
The Journal of Immunology. 185:679-687
Th17 cells have been named after their signature cytokine IL-17 and accumulating evidence indicates their involvement in the induction and progression of inflammatory diseases. In addition to IL-17 single-producing T cells, IL-17/IFN-γ double-positi
Autor:
Ware G. Kuschner, Lynn M. Hildemann, Wayne R. Ott, James Canfield, Karin M. Abitorabi, Sebnem Guvenc-Tuncturk, Gordon K. Mak, Rene de Waal Malefyt, Terrill K. McClanahan, Jeanine D. Mattson, Robert B. Fick, Brian M. Haus, Beth Basham, Madhuri Agrawal, Bela Desai, Wei Ding
Publikováno v:
Experimental Lung Research. 34:631-662
Chronic obstructive pulmonary diseases (COPD) may increase air pollution-related mortality. The relationship of immune mechanisms to mortality caused by fine particulates in healthy and COPD populations is incompletely understood. The objective of th
Autor:
Maria-Christina Malinao, Manjari Nathan, Jeanine D. Mattson, Beth Basham, Maribel Beaumont, Harman S Paintal, Bela Desai, Ganesh Krishna, Rene de Waal Malefyt, Terrill K. McClanahan, James Canfield, Fran Shen, Robert B. Fick, Ying Li
Publikováno v:
Experimental lung research. 37(4)
Idiopathic interstitial pneumonias are a group of idiopathic interstitial lung diseases of which idiopathic pulmonary fibrosis (IPF) is the lesion of usual interstitial pneumonia. Although the pathogenic mechanisms remain incompletely understood, dis
Autor:
Holden T, Maecker, J Philip, McCoy, Michael, Amos, John, Elliott, Adolfas, Gaigalas, Lili, Wang, Richard, Aranda, Jacques, Banchereau, Chris, Boshoff, Jonathan, Braun, Yael, Korin, Elaine, Reed, Judy, Cho, David, Hafler, Mark, Davis, C Garrison, Fathman, William, Robinson, Thomas, Denny, Kent, Weinhold, Bela, Desai, Betty, Diamond, Peter, Gregersen, Paola, Di Meglio, Paola, DiMeglio, Frank O, Nestle, Frank, Nestle, Mark, Peakman, Federica, Villanova, Federica, Villnova, John, Ferbas, Elizabeth, Field, Aaron, Kantor, Thomas, Kawabata, Wendy, Komocsar, Michael, Lotze, Jerry, Nepom, Hans, Ochs, Raegan, O'Lone, Deborah, Phippard, Scott, Plevy, Stephen, Rich, Mario, Roederer, Dan, Rotrosen, Jung-Hua, Yeh
Publikováno v:
Nature immunology. 11(11)
Complexities in sample handling, instrument setup and data analysis are barriers to the effective use of flow cytometry to monitor immunological parameters in clinical trials. The novel use of a central laboratory may help mitigate these issues.
Autor:
Robert B. Fick, G. Ayanoglu, Shaun P. Reece, Robert L. Wardle, R. de Waal Malefyt, Jeffrey Grein, Bela Desai, Stephen Olmstead, Terri McClanahan, M. R. Van Scott, Jeanine D. Mattson
Publikováno v:
The European respiratory journal. 37(3)
The aim of the present study was to determine whether systemic sensitisation and chronic aeroallergen challenge in macaques replicate the classical and emerging immunology and molecular pathology of human asthma. Macaques were immunised and periodica
Autor:
Robert B. Fick, Bela Desai, Ganesh Krishna, Maria-Christina Malinao, Harman S Paintal, Beth Basham, Maribel Beaumont, Ying Li, M Nathan, Jeanine D. Mattson, R. de Waal Malefyt, F Shen, Terri McClanahan, James Canfield
Publikováno v:
B60. PULMONARY FIBROSIS: THE FIBROBLAST.
Autor:
Erin Murphy, Bela Desai, Svetlana Sadekova, Scott P. Turner, Jeff Grein, Robert A. Kastelein, Katia Boniface, Terrill K. McClanahan, Lisa Raskin, Melanie A. Kleinschek, Rene de Waal Malefyt, Robert H. Pierce, William A. Faubion
Publikováno v:
The Journal of Experimental Medicine
The C-type lectin-like receptor CD161, which has recently been described to promote T cell expansion, is expressed on a discrete subset of human CD4 T cells. The function of such cells, however, has remained elusive. We now demonstrate that CD161(+)