Hydroxytyrosyl punicate: A first overview of a novel phenolipid with antiproliferative and antitrypanosomal activity

Autor: Olga Cruz-López, Elixabet Díaz-de-Cerio, Belén Rubio-Ruiz, Jose Manuel Espejo-Román, Pablo Peñalver, Juan Carlos Morales, Maria Fiorenza Caboni, Ana Conejo-García, Vito Verardo

Publikováno v: Journal of Functional Foods, Vol 117, Iss , Pp 106249- (2024)

Polyunsaturated fatty acids and phenolic compounds are two families of natural products that have been widely investigated for their health benefits. The aim of this study was to prepare the novel phenolipid hydroxytyrosyl punicate (HT-PA) and evalua

Externí odkaz: https://doaj.org/article/28bbfa387633469093e8be25deeb0cfa

In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation

Autor: Belén Rubio-Ruiz, Ana M. Pérez-López, Laura Uson, M. Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L. Hueso, Victor Sebastian, Jesus Santamaria, Asier Unciti-Broceta

Publikováno v: Rubio Ruiz, B, Perez-Lopez, A, Uson, L, Ortega Liebana, M C, Valero, T, Arruebo, M, Hueso, J L, Sebastian, V, Santamaría, J & Unciti-Broceta, A 2023, ' In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys. Overcoming Intracellular Deactivation ', Nano Letters, vol. 23, no. 3, pp. 804-811 . https://doi.org/10.1021/acs.nanolett.2c03593

Bioorthogonal metallocatalysis has opened up a xenobiotic route to perform nonenzymatic catalytic transformations in living settings. Despite their promising features, most metals are deactivated inside cells by a myriad of reactive biomolecules, inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e31e38af801c3f6ddec213e6a08b54a
https://doi.org/10.1021/acs.nanolett.2c03593

PERSONAL ATTENTION PROGRAM TO UNIVERSITY STUDENTS WITH SPECIAL EDUCATIONAL NEEDS

Autor: María José Alférez, Beatriz Clares Naveros, Ana Conejo García, Olga Cruz López, Emilio García Fernández, Rafael Jesús Giménez Martínez, María Del Carmen González García, Enrique González Muñoz, Josefa María González Pérez, Juan Antonio González Vera, Alberto Molinero García, Ana Isabel Del Moral García, Celia Monteagudo Sánchez, Ricardo Navarrete Casas, Francisco Ocaña Peinado, José Manuel Paredes Martínez, Miguel Romero Pérez, Belén Rubio Ruiz, María José Ruedas Rama, Manuel Sánchez Polo, Javier Valverde Pozo, Rosa Castilla Ríos, Carlos Francisco García Jiménez, Antonio Lozano Ortega, Ángel Martínez Avilés, Alberto González Muñoz, Lidya González Robles, Javier Sepúlveda Villodres, Eva María Talavera Rodríguez

Publikováno v: INTED2023 Proceedings.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06ed6a5442338077c486f97a2331f224
https://doi.org/10.21125/inted.2023.0143

A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo

Autor: Catherine Adam, Thomas L. Bray, Ana M. Pérez-López, Ee Hong Tan, Belén Rubio-Ruiz, Daniel J. Baillache, Douglas R. Houston, Mark J. Salji, Hing Y. Leung, Asier Unciti-Broceta

Publikováno v: Adam, C, Bray, T, Perez-Lopez, A, Tan, E H, Rubio Ruiz, B, Baillache, D, Houston, D R, Salji, M J, Leung, H Y & Unciti-Broceta, A 2022, ' A 5-FU precursor designed to evade anabolic and catabolic drug pathways and activated by Pd chemistry in vitro and in vivo ', Journal of Medicinal Chemistry, vol. 65, no. 1, pp. 552-561 . https://doi.org/10.1021/acs.jmedchem.1c01733

5-Fluorouracil (5-FU) is an antineoplastic antimetabolite that is widely administered to cancer patients by bolus injection, especially to those suffering from colorectal and pancreatic cancer. Because of its suboptimal route of administration and do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5f8ba00f4b02191c9fbb77c71335c2
https://hdl.handle.net/10668/22589

Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents

Autor: Belén Rubio-Ruiz, Carmen Torres-Sanchez, Ana M. Pérez-López, Mohammad N. Alqahtani, Asier Unciti-Broceta

Publikováno v: Torres-sánchez, C, Pérez-lópez, A M, Alqahtani, M N, Unciti-broceta, A & Rubio-ruiz, B 2018, ' Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents ', New journal of chemistry . https://doi.org/10.1039/C8NJ05704D

Novel palladium (Pd)-loaded titanium (Ti) devices with high biocompatibility and catalytic activity were prepared using a range of fabrication methods such as powder metallurgy (i.e. sintering with and without space-holder), sputtering, pulsed laser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563cd7697cbfd2344e83891b71add72c
https://doi.org/10.1039/c8nj05704d