Evaluation of clinical events and costs associated with the addition of dapagliflozin to chronic kidney disease treatment: Cost offset analysis

Autor: Juan Francisco Navarro-González, Alberto Ortiz, Ana Cebrián Cuenca, Lluís Segú, Belén Pimentel, Unai Aranda, Blanca Lopez-Chicheri, Margarita Capel, Elisenda Pomares Mallol, Christian Caudron, Juan José García Sánchez, Roberto Alcázar Arroyo

Publikováno v: Nefrología (English Edition), Vol 44, Iss 6, Pp 857-867 (2024)

Background and objectives: Chronic kidney disease (CKD) is a serious health problem with an increasing clinical, social and economic impact in advanced stages. Dapagliflozin is a sodium-glucose cotransporter-2 inhibitor that reduces the risk of CKD p

Externí odkaz: https://doaj.org/article/e723d232252d42eca0056cf8db3cd1b4

Biocompatible Films with Tailored Spectral Response for Prevention of DNA Damage in Skin Cells

Autor: Mauricio E. Calvo, Rebeca Núñez-Lozano, Belén Pimentel, Hernán Míguez, Guillermo de la Cueva-Méndez, José R. Castro-Smirnov

Publikováno v: Advanced Healthcare Materials
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname

Protection from solar radiation is commonly achieved through the use of UV organic absorbers, such as benzophenones or benzotriazoles, often combined with inorganic materials such as TiO2 or ZnO2, supplied in the form of submicron size particles.[1]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a5df1259646a370b792c29958459cd
https://doi.org/10.1002/adhm.201500223

Gene and cell survival: lessons from prokaryotic plasmid R1

Autor: Guillermo de la Cueva-Méndez, Belén Pimentel

Publikováno v: EMBO reports. 8:458-464

Plasmids are units of extrachromosomal genetic inheritance found in all kingdoms of life. They replicate autonomously and undergo stable propagation in their hosts. Despite their small size, plasmid replication and gene expression constitute a metabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83662eb77936dd1d33fa0aa5d0d37bf
https://doi.org/10.1038/sj.embor.7400957

'Smartening' anticancer therapeutic nanosystems using biomolecules

Autor: Guillermo de la Cueva-Méndez, Rebeca Núñez-Lozano, Manuel Cano, Belén Pimentel

Publikováno v: Current opinion in biotechnology. 35

To be effective, anticancer agents must induce cell killing in a selective manner, something that is proving difficult to achieve. Drug delivery systems could help to solve problems associated with the lack of selectivity of classical chemotherapeuti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3285be2a5c96c14471a3427fa1ea92c
https://pubmed.ncbi.nlm.nih.gov/26277646

Apoptotic cell death of proliferating neuroepithelial cells in the embryonic retina is prevented by insulin

Autor: E J de la Rosa, Belén Pimentel, F de Pablo, B Díaz

Publikováno v: European Journal of Neuroscience. 11:1624-1632

The role of programmed cell death is well established for connecting neurons. Conversely, much less is known about apoptosis affecting proliferating neuroepithelial cells. Chick retina from day 4 to day 6 of embryonic development (E), essentially pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52129e235235bc8c5a4662d4cfa75c3e
https://doi.org/10.1046/j.1460-9568.1999.00577.x