Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Belén Martı́n-Matute"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102147- (2023)
Summary: Unnatural amino acids are valuable building blocks with numerous applications. Here, we present a quantitative technique for accessing mono-N-functionalized amino acids directly from unprotected substrates using alcohols as alkylating agents
Externí odkaz:
https://doaj.org/article/273baffe1857498d82d458d03a1939c0
Autor:
Marc L. Snapper, Peng Zhang, Belinda T. Lee, Thomas O. Schrader, Belén Martı́n-Matute, Christopher R. Kauffman
Publikováno v:
Tetrahedron. 60:7391-7396
(PCy3)2Cl2RuCHPh-catalyzed Kharasch additions of trihaloalkanes across olefins provide polyhalogenated adducts, which upon hydrolysis furnish α,β-unsaturated ketones, aldehydes, or γ-hydroxybutenolides. This two-step process represents an overa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69759194955d604a6e1bc5c52a7694ea
https://doi.org/10.1016/j.tet.2004.06.066
https://doi.org/10.1016/j.tet.2004.06.066
Autor:
Peng Zhang, Christopher R. Kauffman, Belinda T. Lee, Belén Martı́n-Matute, Marc L. Snapper, Thomas O. Schrader
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3083ddd1ad74ce7d9d8f37628284e6a
https://doi.org/10.1002/chin.200446035
https://doi.org/10.1002/chin.200446035
Autor:
Amparo Sanz-Marco, Samuel Martinez-Erro, Martin Pauze, Enrique Gómez-Bengoa, Belén Martín-Matute
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nucleophiles cannot be directly reacted with enolates due to polarity mismatching. Here, the authors developed an umpolung strategy for the selective synthesis of α-alkoxy carbonyl compounds by reaction of iridium enolates with nucleophilic alcohols
Externí odkaz:
https://doaj.org/article/4512de0e8120421faf358a40d8a268ba
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102467- (2021)
Summary: Late-stage functionalization (LSF) has over the past years emerged as a powerful approach in the drug discovery process. At its best, it allows for rapid access to new analogues from a single drug-like molecule, bypassing the need for de nov
Externí odkaz:
https://doaj.org/article/c92a73b86d4b4f5c91d97ac885ddb370
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 50 (2007)
The scale-up of the ruthenium- and enzyme-catalyzed dynamic kinetic resolution (DKR) of (rac)-1-phenylethanol (2) is addressed. The immobilized lipase Candida antarctica lipase B (CALB) was employed for the resolution, which shows high enantioselecti
Externí odkaz:
https://doaj.org/article/063b7e20c368446a9a624c1f007d407c