Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity

Autor: Hanna, Joachim, Beke, Flavio, O’Brien, Louise M, Kapeni, Chrysa, Chen, Hung-Chang, Carbonaro, Valentina, Kim, Alexander B, Kishore, Kamal, Adolph, Timon E, Skjoedt, Mikkel-Ole, Skjoedt, Karsten, De La Roche, Marc, De La Roche, Maike

Funder: This work was supported by Cancer Research UK (MdlR (A22257), FB, LMOB, CK, H-CC, VC); Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (MdlR (WT107609); LMOB); Gates Cambridge Trust (AK); JH is undertaking

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https://www.repository.cam.ac.uk/handle/1810/340132

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Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.

Autor: Hanna J; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Beke F; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., O'Brien LM; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Kapeni C; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Chen HC; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Carbonaro V; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Kim AB; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Kishore K; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK., Adolph TE; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria., Skjoedt MO; Rigshospitalet - University Hospital Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Institute of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Skjoedt K; University of Southern Denmark, J.B.Winslows Vej, 5000, Odense C, Denmark., de la Roche M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., de la Roche M; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK. maike.delaroche@cruk.cam.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2022 Jul 14; Vol. 13 (1), pp. 4075. Date of Electronic Publication: 2022 Jul 14.