Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Beiyun Wang"'
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103255- (2022)
Backgrounds: Subjective cognitive decline (SCD), one of the important clinical indicators for preclinical Alzheimer's disease (AD), is primarily defined as self-perceived cognitive decline without objective evidence for cognitive impairment. However,
Externí odkaz:
https://doaj.org/article/cb38a73525e4428aa01330fdfa2b5257
Autor:
Jin Lu, Lili Wan, Yuan Zhong, Qi Yu, Yonglong Han, Pengguo Chen, Beiyun Wang, Wei Li, Ya Miao, Cheng Guo
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 188-195 (2015)
The therapeutic response rates of patients to donepezil vary from 20% to 60%, one of the reasons is their genetic differences in donepezil-metabolizing enzymes, which directly influence liver metabolism. However, the mechanism of donepezil metabolism
Externí odkaz:
https://doaj.org/article/f14b10a288104cc8a1d4bfae5c2aa3a4
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 3, Pp 1142-1150 (2015)
Background/Aims: Diabetes and Alzheimer's disease are often associated with each other, whereas the relationship between two diseases is ill-defined. Although hyperglycemia during diabetes is a major cause of encephalopathy, diabetes may also cause c
Externí odkaz:
https://doaj.org/article/7038c29dd14f43a095764dda1d8aeaff
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:513-520
ObjectiveAmyloid-β positron emission tomography (Aβ-PET) scan has been proposed to detect amyloid-β (Aβ) deposition in the brain. However, this approach is costly and not ideal for the early diagnosis of Alzheimer’s disease. Blood-based Aβ mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5093eda154097c70d8063535754e995
https://doi.org/10.1136/jnnp-2021-327864
https://doi.org/10.1136/jnnp-2021-327864
Background: Previous studies reported subjective cognitive decline (SCD) linked to underlying the biomarker of early AD pathology. There is a lack of studies on whether structural brain changes and how cerebral morphology in association with verbal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b65444f8184edb113e26beff4159772
https://doi.org/10.21203/rs.3.rs-55458/v1
https://doi.org/10.21203/rs.3.rs-55458/v1
Publikováno v:
Biochemical and Biophysical Research Communications. 490:336-342
The aim of our study was to investigate to investigate the effect of myricetin on Alzheimer's disease (AD) and its underlying mechanisms. In our study, Myricetin effectively attenuated Fe2+-induced cell death in SH-SY5Y cells in vitro. In a mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8106ce16c72323fa8a720308c693f652
https://doi.org/10.1016/j.bbrc.2017.06.045
https://doi.org/10.1016/j.bbrc.2017.06.045
Publikováno v:
Aging (Albany NY)
The development of diabetic encephalopathy (DE) is enhanced by inflammatory macrophages, and is suppressed by macrophage autophagy. However, the molecular signaling that controls macrophage autophagy in DE remains ill-defined. Here, DE is induced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918e52400f6e949f2e34fedd73129db9
https://pubmed.ncbi.nlm.nih.gov/30346929
https://pubmed.ncbi.nlm.nih.gov/30346929
Publikováno v:
Revista da Associação Médica Brasileira v.64 n.5 2018
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Volume: 64, Issue: 5, Pages: 428-432, Published: MAY 2018
Revista da Associação Médica Brasileira, Vol 64, Iss 5, Pp 428-432
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Volume: 64, Issue: 5, Pages: 428-432, Published: MAY 2018
Revista da Associação Médica Brasileira, Vol 64, Iss 5, Pp 428-432
SUMMARY OBJECTIVE To analyze the effect of mecobalamin on the early-functional outcomes of patients with ischemic stroke and H-type hypertension. METHODS From October of 2014 to October of 2016, 224 cases of ischemic stroke and H-type hypertension we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f771d30ba0d1f668a5ac309fd2a1d
https://pubmed.ncbi.nlm.nih.gov/30304141
https://pubmed.ncbi.nlm.nih.gov/30304141
Publikováno v:
International Urology and Nephrology. 45:1179-1185
To evaluate the protective effects of alprostadil on contrast-induced nephropathy (CIN) in elderly patients. We randomized 370 patients into the control or alprostadil group. The patients in the control group were injected with 100 ml sterile saline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639f3ea2a235f7a230a81d57248534dc
https://doi.org/10.1007/s11255-013-0484-1
https://doi.org/10.1007/s11255-013-0484-1
Publikováno v:
The American Journal of the Medical Sciences. 345:222-226
The aim of this study was to evaluate the effect of CYP2D6*10 and APOE polymorphisms on both steady-state plasma concentrations (Cp) and clinical response of donepezil in patients with mild-to-moderate Alzheimer's disease (AD).A total of 110 Chinese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9bebf06b2a0cdd1515fc58ba077520
https://doi.org/10.1097/maj.0b013e318255a8f9
https://doi.org/10.1097/maj.0b013e318255a8f9