Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Beiyang Wei"'
Autor:
Javier Sánchez-Pozo, Alexander J. Baker-Williams, Mark R. Woodford, Renee Bullard, Beiyang Wei, Mehdi Mollapour, William G. Stetler-Stevenson, Gennady Bratslavsky, Dimitra Bourboulia
Publikováno v:
iScience, Vol 1, Iss , Pp 87-96 (2018)
Summary: The tissue inhibitor of metalloproteinases 2 (TIMP-2) is a specific endogenous inhibitor of matrix metalloproteinase 2 (MMP-2), which is a key enzyme that degrades the extracellular matrix and promotes tumor cell invasion. Although the TIMP-
Externí odkaz:
https://doaj.org/article/162e0a659f004ddc931c533bf3fe8b79
Autor:
Mehdi Mollapour, Alexander J. Baker-Williams, William G. Stetler-Stevenson, Gennady Bratslavsky, Renee Bullard, Beiyang Wei, Mark R. Woodford, Javier Sánchez-Pozo, Dimitra Bourboulia
Publikováno v:
iScience, Vol 1, Iss, Pp 87-96 (2018)
Summary: The tissue inhibitor of metalloproteinases 2 (TIMP-2) is a specific endogenous inhibitor of matrix metalloproteinase 2 (MMP-2), which is a key enzyme that degrades the extracellular matrix and promotes tumor cell invasion. Although the TIMP-
Publikováno v:
Biochemistry. 56(49)
Tissue inhibitor of metalloprotease-2 (TIMP-2) is a secreted 21 kDa multifunctional protein first described as an endogenous inhibitor of matrix metalloproteinases (MMPs) that prevents breakdown of the extracellular matrix often observed in chronic d
Autor:
B Isaac, Dimitra Bourboulia, Beiyang Wei, Huiying Han, William G. Stetler-Stevenson, Sandra Jensen-Taubman
Publikováno v:
Oncogene. 33:1198-1206
The side population (SP) in human lung cancer cell lines and tumors is enriched with cancer stem cells. An endogenous inhibitor of angiogenesis known as tissue inhibitor of matrix metalloproteinase-2 (TIMP-2), characterized for its ability to inhibit
Autor:
William G. Stetler-Stevenson, Beiyang Wei, John J. Caterina, Sandra Jensen-Taubman, Dimitra Bourboulia, Clifford J Kwityn, Liliana Guedez
Publikováno v:
Journal of Immunotherapy. 35:502-512
Angiogenesis and inflammation are important therapeutic targets in non-small cell lung cancer (NSCLC). It is well known that proteolysis mediated by matrix metalloproteinases (MMPs) promotes angiogenesis and inflammation in the tumor microenvironment
Autor:
William G. Stetler-Stevenson, Dimitra Bourboulia, Huiying Han, Tania Chatterjee, Beiyang Wei, Matthew Rittler, Sandra Jensen-Taubman
Publikováno v:
The American Journal of Pathology. 179:2589-2600
Tissue inhibitor of matrix metalloproteinase–2 (TIMP-2) belongs to a small family of endogenous proteins that inhibits a group of enzymes, the matrix metalloproteinases (MMPs). TIMP-2 inhibits endothelial cell proliferation and migration in vitro a
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
In the present study we examine the effects of tissue inhibitor of metalloproteinases-2 (TIMP-2) on the phosphorylation status of specific phosphotyrosine residues on the vascular endothelial cell growth factor receptor-2 (VEGFR-2) cytoplasmic tail a
Autor:
Beiyang Wei, William G. Stetler-Stevenson, Dong-Wan Seo, Pyeung-Hyeun Kim, Jeung Whan Han, Yong Kee Kim, Young-Rak Cho, Soo Hyeon Kim, Hyun Jae Yoon, Tere Diaz, Seok-Hyun Eom
Publikováno v:
Microvascular Research. 76:145-151
We have previously reported that tissue inhibitor of metalloproteinases-2 (TIMP-2), an endogenous inhibitor of matrix metalloproteinase, modulates angiogenic responses through the MMP inhibition-independent activity. In this study, we investigate the
Publikováno v:
The FASEB Journal. 29
Publikováno v:
Oncogene. 25:4230-4234
We previously demonstrated that TIMP-2 increases the association of Crk with C3G and via subsequent activation of Rap1 enhances the expression of RECK, a membrane-anchored MMP inhibitor. In the present study, we investigate the mechanism of how the T