Pooling individual participant data from randomized controlled trials: Exploring potential loss of information

Autor: Van Wanrooij, Lennard L, Hoevenaar-Blom, Marieke P, Coley, Nicola, Ngandu, Tiia, Meiller, Yannick, Guillemont, Juliette, Rosenberg, Anna, Beishuizen, Cathrien RL, Moll Van Charante, Eric P, Soininen, Hilkka, Brayne, Carol, Andrieu, Sandrine, Kivipelto, Miia, Richard, Edo

BACKGROUND: Pooling individual participant data to enable pooled analyses is often complicated by diversity in variables across available datasets. Therefore, recoding original variables is often necessary to build a pooled dataset. We aimed to quant

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Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context.

Autor: Akenine U; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden ulrika.akenine@ki.se., Barbera M; Institute of Clinical Medicine, Department of Neurology, University of Eastern Finland, Kuopio, Finland., Beishuizen CR; Department of General Practice, Amsterdam UMC/University of Amsterdam, Amsterdam, The Netherlands., Fallah Pour M; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Division of Occupational Therapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Guillemont J; INSERM, University of Toulouse, Toulouse, France., Rosenberg A; Institute of Clinical Medicine, Department of Neurology, University of Eastern Finland, Kuopio, Finland., Coley N; INSERM, University of Toulouse, Toulouse, France.; Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France., Mangialasche F; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Salo L; Institute of Clinical Medicine, Department of Neurology, University of Eastern Finland, Kuopio, Finland., Savy S; INSERM, University of Toulouse, Toulouse, France., Pols AJ; Section of Medical Ethics, Department of General Practice, Amsterdam UMC/University of Amsterdam, Amsterdam, The Netherlands., Andrieu S; INSERM, University of Toulouse, Toulouse, France.; Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France., Richard E; Department of Neurology, Amsterdam UMC/University of Amsterdam, Amsterdam, The Netherlands.; Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Soininen H; Institute of Clinical Medicine, Department of Neurology, University of Eastern Finland, Kuopio, Finland.; Neurocenter Finland, Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Moll van Charante E; Department of General Practice, Amsterdam UMC/University of Amsterdam, Amsterdam, The Netherlands., Kivipelto M; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Theme Aging, Karolinska University Hospital, Stockholm, Sweden.; R&D Unit, Stockholms Sjukhem, Stockholm, Sweden.; Neuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, United Kingdom.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.

Publikováno v: BMJ open [BMJ Open] 2020 Aug 06; Vol. 10 (8), pp. e037050. Date of Electronic Publication: 2020 Aug 06.