Zobrazeno 1 - 10
of 978
pro vyhledávání: '"Beisel, P."'
Autor:
Rebekka Wegmann, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Ricardo Coelho, Cinzia Esposito, Joanna Ficek-Pascual, Sandra Goetze, Gabriele Gut, Francis Jacob, Andrea Jacobs, Jack Kuipers, Ulrike Lischetti, Julien Mena, Emanuela S. Milani, Michael Prummer, Jacobo Sarabia Del Castillo, Franziska Singer, Sujana Sivapatham, Nora C. Toussaint, Oliver Vilinovszki, Mattheus H. E. Wildschut, Tharshika Thavayogarajah, Disha Malani, The TumorProfiler Consortium, Rudolf Aebersold, Marina Bacac, Niko Beerenwinkel, Christian Beisel, Bernd Bodenmiller, Viola Heinzelmann-Schwarz, Viktor H. Koelzer, Mitchell P. Levesque, Holger Moch, Lucas Pelkmans, Gunnar Rätsch, Markus Tolnay, Andreas Wicki, Bernd Wollscheid, Markus G. Manz, Berend Snijder, Alexandre P. A. Theocharides
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug profiling (pharmacoscopy) wit
Externí odkaz:
https://doaj.org/article/d909919fc46044dd87b6ffb2a1e8a194
Publikováno v:
2023 IEEE International Conference on Quantum Computing and Engineering (QCE)
With the emergence of quantum computing, a growing number of quantum devices is accessible via cloud offerings. However, due to the rapid development of the field, these quantum-specific service offerings vary significantly in capabilities and requir
Externí odkaz:
http://arxiv.org/abs/2304.12718
Autor:
Truger, Felix, Barzen, Johanna, Bechtold, Marvin, Beisel, Martin, Leymann, Frank, Mandl, Alexander, Yussupov, Vladimir
Due to low numbers of qubits and their error-proneness, Noisy Intermediate-Scale Quantum (NISQ) computers impose constraints on the size of quantum algorithms they can successfully execute. State-of-the-art research introduces various techniques addr
Externí odkaz:
http://arxiv.org/abs/2303.06133
Autor:
Cristiano Miranda de Araujo, Pedro Felipe de Jesus Freitas, Aline Xavier Ferraz, Isabella Christina Costa Quadras, Bianca Simone Zeigelboim, Sidnei Priolo Filho, Svenja Beisel-Memmert, Angela Graciela Deliga Schroder, Elisa Souza Camargo, Erika Calvano Küchler
Publikováno v:
Head & Face Medicine, Vol 20, Iss 1, Pp 1-10 (2024)
Abstract Background Cranial, facial, nasal, and maxillary widths have been shown to be significantly affected by the individual’s sex. The present study aims to use measurements of dental arch and maxillary skeletal base to determine sex, employing
Externí odkaz:
https://doaj.org/article/38abdb59f32a4ea49cf41429ea255ea2
Autor:
Aset Khakimzhan, Ziane Izri, Seth Thompson, Oleg Dmytrenko, Patrick Fischer, Chase Beisel, Vincent Noireaux
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Integral and interacting membrane proteins (IIMPs) constitute a vast family of biomolecules that perform essential functions in all forms of life. However, characterizing their interactions with lipid bilayers remains limited due to challeng
Externí odkaz:
https://doaj.org/article/445f3b0e9b414eba9eb73ea7730dc430
Autor:
Chunlei Jiao, Natalia L. Peeck, Jiaqi Yu, Mohammad Ghaem Maghami, Sarah Kono, Daphne Collias, Sandra L. Martinez Diaz, Rachael Larose, Chase L. Beisel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Many CRISPR-Cas immune systems generate guide (g)RNAs using trans-activating CRISPR RNAs (tracrRNAs). Recent work revealed that Cas9 tracrRNAs could be reprogrammed to convert any RNA-of-interest into a gRNA, linking the RNA’s presence to
Externí odkaz:
https://doaj.org/article/fae1f70b488348a591a8db8b7fd3dca3
Autor:
Gabriela Fonseca-Souza, Amanda Renostro-Souza, Lhorrany Alves-Souza, Geraldo Thedei Junior, Maria Angélica Hueb de Menezes-Oliveira, Lívia Azeredo Alves Antunes, Svenja Beisel-Memmert, Christian Kirschneck, Juliana Feltrin-Souza, Erika Calvano Küchler
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background The evidence in the literature suggests that some skeletal or dental malocclusions are involved with dental development, resulting in advanced or delayed dental age (DA). The purpose of this systematic review was to investigate th
Externí odkaz:
https://doaj.org/article/bcf467d6e94e451782a41eb57e0c6c28
Autor:
Aranzazu Arias-Rojas, Adini Q Arifah, Georgia Angelidou, Belal Alshaar, Ursula Schombel, Emma Forest, Dagmar Frahm, Volker Brinkmann, Nicole Paczia, Chase L Beisel, Nicolas Gisch, Igor Iatsenko
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012462 (2024)
Multiple peptide resistance factor (MprF) confers resistance to cationic antimicrobial peptides (AMPs) in several pathogens, thereby enabling evasion of the host immune response. The role of MprF in commensals remains, however, uncharacterized. To cl
Externí odkaz:
https://doaj.org/article/0c6cb570cd50400c90092644d5058a49
Autor:
Yanying Yu, Sandra Gawlitt, Lisa Barros de Andrade e Sousa, Erinc Merdivan, Marie Piraud, Chase L. Beisel, Lars Barquist
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract CRISPR interference (CRISPRi) is the leading technique to silence gene expression in bacteria; however, design rules remain poorly defined. We develop a best-in-class prediction algorithm for guide silencing efficiency by systematically inve
Externí odkaz:
https://doaj.org/article/b3fe9104d58c45dab45798f7f6947605
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 666-680 (2023)
CRISPR technologies comprising a Cas nuclease and a guide RNA (gRNA) can utilize multiple gRNAs to enact multi-site editing or regulation in the same cell. Nature devised a highly compact means of encoding gRNAs in the form of CRISPR arrays composed
Externí odkaz:
https://doaj.org/article/fde7e1846cdc41ca814ee8c762767e35