Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Beini Sun"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Regorafenib (REGO) is a synthetic oral multi-kinase inhibitor with potent antitumor activity. In this study, we investigate the molecular mechanisms by which REGO induces apoptosis. REGO induced cytotoxicity, inhibited the proliferation and
Externí odkaz:
https://doaj.org/article/41950743ce0a4945a4f770cc0e68213c
Autor:
Hongce Chen, Beini Sun, Han Sun, Lingjun Xu, Guihao Wu, Zhuang Tu, Xuecheng Cheng, Xuhong Fan, Zihao Mai, Qiling Tang, Xiaoping Wang, Tongsheng Chen
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Metformin (Met) exhibits anticancer ability in various cancer cell lines. This report aims to explore the exact molecular mechanism of Met-induced apoptosis in HCT116 cells, a human colorectal cancer cell line. Met-induced reactive oxygen sp
Externí odkaz:
https://doaj.org/article/ec5ff3f3032d4cd888f7caf48a7b9838
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background There has been a great interest in developing strategies for enhancing antigen delivery to the mucosal immune system as well as identifying mucosal active immunostimulating agents. To elevate the potential of O-2ʹ-Hydroxypropyl t
Externí odkaz:
https://doaj.org/article/839c6216e5ca4d32b16f2a6a92e6238c
Publikováno v:
Polymers, Vol 10, Iss 4, p 462 (2018)
Chitosan is a biodegradable natural polymer with many advantages such as nontoxicity, biocompatibility, and biodegradability. It can be applied in many fields, especially in medicine. As a delivery carrier, it has great potential and cannot be compar
Externí odkaz:
https://doaj.org/article/c7089b47a4bb471c86c861ee5d4b2cf5
Publikováno v:
ACS Applied Materials & Interfaces. 14:52691-52701
Nasal administration for vaccine delivery is a novel non-invasive vaccine administration approach that can induce local or systemic immune responses and overcome the disadvantages caused by traditional injectable administration. However, mucosal vacc
Autor:
Guihao Wu, Cifeng Zhang, Lingjun Xu, Hongce Chen, Xuhong Fan, Beini Sun, Qiling Tang, Yongtong Zhan, Tongsheng Chen, Xiaoping Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 609:93-99
Osteoarthritis occurs when the number of senescent chondrocytes in the joints reaches an intolerable level. The purpose of our study was to explore the therapeutic effect and mechanism of action of A-1331852 in osteoarthritis. Doxorubicin and etoposi
Autor:
Beini Sun
Publikováno v:
Научное мнение. :105-110
Autor:
Zihao Mai, Han Sun, Fangfang Yang, Mengyan Du, Xuecheng Cheng, Hongce Chen, Beini Sun, Junlin Wen, Xiaoping Wang, Tongsheng Chen
Publikováno v:
The international journal of biochemistrycell biology.
Although Bcl-xL has been shown to retrotranslocate Bax from mitochondria to cytosol, other studies have found that Bcl-xL also stabilizes the mitochondrial localization of Bax. It is still unclear what causes the difference in Bcl-xL-regulated Bax lo
The classification of apoptotic and living cells is significant in drug screening and treating various diseases. Conventional supervised methods require a large amount of prelabelled data, which is often costly and consumes immense human resources in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca784a45b56d3e1cfe3d48ee2d5a632
https://doi.org/10.21203/rs.3.rs-1956878/v1
https://doi.org/10.21203/rs.3.rs-1956878/v1
Autor:
Beini Sun
Publikováno v:
THEORIA: педагогика, экономика, право. :51-56