Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Beina Teng"'
Autor:
Janina Müller-Deile, Heiko Schenk, Philipp Niggemann, Patricia Bolaños-Palmieri, Beina Teng, Alysha Higgs, Lynne Staggs, Hermann Haller, Patricia Schroder, Mario Schiffer
Publikováno v:
Biology Open, Vol 8, Iss 3 (2019)
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of po
Externí odkaz:
https://doaj.org/article/fe6664bad2f54abea4dcb772380b8b53
Autor:
Astrid Behnert, Marvin J Fritzler, Beina Teng, Meifeng Zhang, Frank Bollig, Hermann Haller, Andrej Skoberne, Michael Mahler, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61669 (2013)
The phospholipase A2 receptor (PLA2R) was recently discovered as a target autoantigen in patients with idiopathic membranous nephropathy (IMN). Published evidence suggests that the autoantibodies directed towards a conformation dependent epitope are
Externí odkaz:
https://doaj.org/article/20e17bc829c645a59d5b23f769528b16
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
ADF/cofilins are the major regulators of actin dynamics in mammalian cells. The activation of ADF/cofilins is controlled by a variety of regulatory mechanisms. Dysregulation of ADF/cofilin may result in loss of a precisely organized actin cytoskeleta
Externí odkaz:
https://doaj.org/article/d543079df62b49b3a42f70230482dce9
Autor:
Irini Tossidou, Beina Teng, Jan Menne, Nelli Shushakova, Joon-Keun Park, Jan U Becker, Friedrich Modde, Michael Leitges, Hermann Haller, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10185 (2010)
BACKGROUND: Microalbuminuria is an early lesion during the development of diabetic nephropathy. The loss of high molecular weight proteins in the urine is usually associated with decreased expression of slit diaphragm proteins. Nephrin, is the major
Externí odkaz:
https://doaj.org/article/5555e59ccd114717a3220ab3f63553b9
Autor:
Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12626 (2010)
BACKGROUND: Podocytes are highly specialized epithelial cells on the visceral side of the glomerulus. Their interdigitating primary and secondary foot processes contain an actin based contractile apparatus that can adjust to changes in the glomerular
Externí odkaz:
https://doaj.org/article/1d197e41d627485087b1d5bdf9a70c5d
Autor:
Janina Müller-Deile, Tilman Jobst-Schwan, Mario Schiffer, Ruth I. Johnson, Hermann Haller, Thomas F. Reubold, Irini Tossidou, Laura de Jonge, Susanne Eschenburg, Patricia Bolanos-Palmieri, Beina Teng, Dana M Drost, Christian Kardinal, Kirstin Worthmann, Jonas M. Willerding, Patricia Schroder
Publikováno v:
J Am Soc Nephrol
BACKGROUND: CD2-associated protein (CD2AP), a slit diaphragm–associated scaffolding protein involved in survival and regulation of the cytoskeleton in podocytes, is considered a “stabilizer” of the slit diaphragm complex that connects the slit
Autor:
Flavia Wiehler, Robert Greite, Lena Schiffer, Katja Derlin, Wilfried Gwinner, Lars Pape, Christian Lerch, Mario Schiffer, Beina Teng, Michael Mengel, Anja Thorenz, Hermann Haller, Faikah Gueler, Kirill Kreimann, Jan Hinrich Bräsen, Sibylle von Vietinghoff, Song Rong
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2552 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 10
International Journal of Molecular Sciences
Volume 20
Issue 10
The presence of B-cell clusters in allogenic T cell-mediated rejection (TCMR) of kidney allografts is linked to more severe disease entities. In this study we characterized B-cell infiltrates in patients with TCMR and examined the role of serum CXCL-
Autor:
Mario Schiffer, Alysha Higgs, Janina Müller-Deile, Philipp Niggemann, Patricia Schroder, Beina Teng, Patricia Bolanos-Palmieri, Hermann Haller, Heiko Schenk, Lynne Staggs
Publikováno v:
Biology Open
Biology Open, Vol 8, Iss 3 (2019)
Biology Open, Vol 8, Iss 3 (2019)
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of po
Autor:
Patricia Schroder, Hermann Haller, Janina Müller-Deile, Lynne Staggs, Ivan Dikic, Irini Tossidou, Mario Schiffer, Beina Teng, Heiko Schenk
Publikováno v:
Diabetes. 65:3667-3679
Diabetic nephropathy (DN) is the major cause of end-stage renal disease worldwide. Podocytes are important for glomerular filtration barrier function and maintenance of size selectivity in protein filtration in the kidney. Podocyte damage is the basi
Autor:
Beina Teng, Hermann Haller, Inga Sörensen-Zender, Mario Schiffer, Nathan Susnik, Veronique Rolli, Anette Melk, Payel Sen, Robert Lindner, Thomas Thum, Sagar Bhayana, Sandor Batkai, Siamak Bahram, Arpita Baisantry, Roland Schmitt
Publikováno v:
Journal of the American Society of Nephrology. 26:2659-2668
Zinc- α 2-glycoprotein (AZGP1) is a secreted protein synthesized by epithelial cells and adipocytes that has roles in lipid metabolism, cell cycling, and cancer progression. Our previous findings in AKI indicated a new role for AZGP1 in the regulati