GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

Autor: Couto Alves, A, De Silva, NMG, Karhunen, V, Sovio, U, Das, S, Taal, HR, Warrington, NM, Lewin, AM, Kaakinen, M, Cousminer, DL, Thiering, E, Timpson, NJ, Bond, TA, Lowry, E, Brown, CD, Estivill, X, Lindi, V, Bradfield, JP, Geller, F, Speed, D, Coin, LJM, Loh, M, Barton, SJ, Beilin, LJ, Bisgaard, H, Bønnelykke, K, Alili, R, Hatoum, IJ, Schramm, K, Cartwright, R, Charles, M, Salerno, V, Clément, K, Claringbould, AAJ, BIOS Consortium, van Duijn, CM, Moltchanova, E, Eriksson, JG, Elks, C, Feenstra, B, Flexeder, C, Franks, S, Frayling, TM, Freathy, RM, Elliott, P, Widén, E, Hakonarson, H, Hattersley, AT, Rodriguez, A, Banterle, M, Heinrich, J, Heude, B, Holloway, JW, Hofman, A, Hyppönen, E, Inskip, H, Kaplan, LM, Hedman, AK, Läärä, E, Prokisch, H, Grallert, H, Lakka, TA, Lawlor, DA, Melbye, M, Ahluwalia, TS, Marinelli, M, Millwood, IY, Palmer, LJ, Pennell, CE, Perry, JR, Ring, SM, Savolainen, MJ, Rivadeneira, F, Standl, M, Sunyer, J, Tiesler, CMT, Uitterlinden, AG, Schierding, W, O’Sullivan, JM, Prokopenko, I, Herzig, K, Smith, GD, O'Reilly, P, Felix, JF, Buxton, JL, Blakemore, AIF, Ong, KK, Jaddoe, VWV, Grant, SFA, Sebert, S, McCarthy, MI, Järvelin, M., Early Growth Genetics (EGG) Consortium

Publikováno v: Science Advances

Copyright © 2019 The Authors. Early childhood growth patterns are associated with adult health, yet the genetic factors and the developmental stages involved are not fully understood. Here, we combine genome-wide association studies with modeling of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c10978d62a197230afd68f4b4b8d7adf
https://researchonline.lshtm.ac.uk/id/eprint/4654552/1/eaaw3095.full.pdf

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

Autor: Barker, A, Sharp, SJ, Timpson, NJ, Bouatia-Naji, N, Warrington, NM, Kanoni, S, Beilin, LJ, Brage, S, Deloukas, P, Evans, DM, Grontved, A, Hassanali, N, Lawlor, DA, Lecoeur, C, Loos, RJ, Lye, SJ, McCarthy, MI, Mori, TA, Ndiaye, NC, Newnham, JP, Ntalla, I, Pennell, CE, St Pourcain, B, Prokopenko, I, Ring, SM, Sattar, N, Visvikis-Siest, S, Dedoussis, GV, Palmer, LJ, Froguel, P, Smith, GD, Ekelund, U, Wareham, NJ, Langenberg, C

Publikováno v: Diabetes; Vol 60
Diabetes
Barker, A, Sharp, S J, Timpson, N J, Bouatia-Naji, N, Warrington, N M, Kanoni, S, Beilin, L J, Brage, S, Deloukas, P, Evans, D M, Grontved, A, Hassanali, N, Lawlor, D A, Lecoeur, C, Loos, R J F, Lye, S J, McCarthy, M I, Mori, T A, Ndiaye, N C, Newnham, J P, Ntalla, I, Pennell, C E, St Pourcain, B, Prokopenko, I, Ring, S M, Sattar, N, Visvikis-Siest, S, Dedoussis, G V, Pahner, L J, Froguel, P, Smith, G D, Ekelund, U, Wareham, N J & Langenberg, C 2011, ' Association of Genetic Loci With Glucose Levels in Childhood and Adolescence A Meta-Analysis of Over 6,000 Children ', Diabetes, vol. 60, no. 6, pp. 1805-1812 . https://doi.org/10.2337/db10-1575

OBJECTIVE-To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents. RESEARCH DESIGN AND METHODS-A total of 16 sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a84719744235d8ec52f6d9dbd1ef90bc

Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts

Autor: Boraska, Vesna, Day-Williams, A, Franklin, CS, Elliott, KS, Panoutsopoulou, K, Tachmazidou, I, Albrecht, E, Bandinelli, S, Beilin, LJ, Bochud, M, Cadby, G, Ernst, F, Evans, DM, Hayward, Caroline, Hicks, AA, Huffman, J, Huth, C, James, AL, Klopp, N, Kolcic, Ivana, Kutalik, Z, Lawlor, DA, Musk, AW, Pehlic, Marina, Pennell, CE, Perry, JR, Peters, A, Polasek, Ozren, St Pourcain, B, Ring, SM, Salvi, E, Schipf, S, Staessen, JA, Teumer, A, Timpson, N, Vitart, V, Warrington, NM, Yaghootkar, H, Zemunik, Tatijana, Zgaga, Lina, An, P, Anttila, V, Borecki, IB, Holmen, J, Ntalla, I, Palotie, A, Pietiläinen, KH, Wedenoja, J, Winsvold, BS, Dedoussis, GV, Kaprio, J, Province, MA, Zwart, JA, Burnier, M, Campbell. H, Cusi, D, Smith, GD, Frayling, TM, Gieger, C, Palmer, LJ, Pramstaller, PP, Rudan, Igor, Völzke, H, Wichmann, HE, Wright, AF, Zeggini, E

Brachial circumference (BC), also known as upper arm or mid arm circumference, can be used as an indicator of muscle mass and fat tissue, which are distributed differently in men and women. Analysis of anthropometric measures of peripheral fat distri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::d402cfc538a54ce49009239afeb9856d
https://www.bib.irb.hr/628510

Associations of maternal prepregnancy body mass index and gestational weight gain with cardio-metabolic risk factors in adolescent offspring: a prospective cohort study.

Autor: Gaillard, R, Welten, M, Oddy, WH, Beilin, LJ, Mori, TA, Jaddoe, VWV, Huang, R‐C, Oddy, W H, Beilin, L J, Mori, T A, Jaddoe, V W V, Huang, R-C

Publikováno v: BJOG: An International Journal of Obstetrics & Gynaecology; Jan2016, Vol. 123 Issue 2, p207-216, 10p

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