Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Beike Wang"'
Autor:
Wei Zhang, Jiegang Yang, Beike Wang, Youtao Lu, Jingbo Yang, Wenqun Zhong, Ziyan Yu, Zhiyuan Qin, Bolin Xiao, Kuiming Wang, Yi Y. Ma, Ravi Amaravadi, Meenhard Herlyn, Junhyong Kim, Xiaowei Xu, Wei Guo
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113352- (2023)
Summary: By sorting receptor tyrosine kinases into endolysosomes, the endosomal sorting complexes required for transport (ESCRTs) are thought to attenuate oncogenic signaling in tumor cells. Paradoxically, ESCRT members are upregulated in tumors. Her
Externí odkaz:
https://doaj.org/article/9ebb2925074d4fe69ec30225145dad72
Publikováno v:
International Journal of Stem Cells. 16:202-214
Autor:
Zhi Wei, Wei Zhang, Yiling Lu, Jie Zhang, Beike Wang, Lawrence N. Kwong, Jiufeng Tan, Gao Zhang, Gordon B. Mills, Wei Guo, Aurelie Beroard, Meenhard Herlyn, Norah Sadek, Min Xiao, Sergio Randell, Vito W. Rebecca, Marilyne Labrie, Eric Sugarman, Jeffrey Field, Xiaowei Xu, Hezhe Lu, Jessie Villanueva
Publikováno v:
Oncogene
Targeting MAPK pathway using a combination of BRAF and MEK inhibitors is an efficient strategy to treat melanoma harboring BRAF-mutation. The development of acquired resistance is inevitable due to the signaling pathway rewiring. Combining western bl
Autor:
Wei Zhang, Wenqun Zhong, Beike Wang, Jiegang Yang, Jingbo Yang, Ziyan Yu, Zhiyuan Qin, Alex Shi, Wei Xu, Cathy Zheng, Lynn M. Schuchter, Giorgos C. Karakousis, Tara C. Mitchell, Ravi Amaravadi, Meenhard Herlyn, Haidong Dong, Phyllis A. Gimotty, George Daaboul, Xiaowei Xu, Wei Guo
Publikováno v:
Dev Cell
Tumor-derived extracellular vesicles (TEVs) suppress the proliferation and cytotoxicity of CD8(+) T cells, thereby contributing to tumor immune evasion. Here we report that the adhesion molecule ICAM-1 co-localizes with PD-L1 on the exosomes; both IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bfc7447478166edf18663039c19655
https://europepmc.org/articles/PMC8881799/
https://europepmc.org/articles/PMC8881799/
Autor:
Zhibin, Li, Siying, Tang, Beike, Wang, Yong, Li, Hao, Huang, Huaiyu, Wang, Penghui, Li, Chengzhang, Li, Paul K, Chu, Xue-Feng, Yu
Publikováno v:
ACS biomaterials scienceengineering. 2(5)
Gold nanorods (AuNRs) with unique plasmonic properties in the near-infrared region have promising biomedical applications but suffer from poor
Autor:
Liyun Dong, Qiwen Man, Beike Wang, Gordon B. Mills, Gao Zhang, Tara C. Mitchell, Hou-Fu Xia, Xiaoming Liu, Wenqun Zhong, Bin Wu, Leonardo F. Antelo, Wei Guo, Rajasekharan Somasundaram, Ting Li, Giorgos C. Karakousis, Wei Zhang, Meenhard Herlyn, Yi-Fang Zhao, Jiegang Yang, Ravi Radhakrishnan, Wei Xu, Yiling Lu, Alexander C. Huang, Suzanne McGettigan, Wu Min, Honghong Sun, Junhyong Kim, Lynn M. Schuchter, Xuepeng Xiong, Youhai H. Chen, E. John Wherry, Ruifeng Yang, Chen Gang, Lei Guan, Xiaowei Xu, Haidong Dong, Youtao Lu, Shujing Liu, Zi-Li Yu
Publikováno v:
Nature
Tumour cells evade immune surveillance by upregulating the surface expression of programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T cells to elicit the immune checkpoint response1,2. Anti-PD-1 antibodies h
Autor:
Paul K. Chu, Beike Wang, Hanhan Xie, Haidi Fu, Zhengbo Sun, Hao Huang, Zhibin Li, Xue-Feng Yu, Guangli Han, Huaiyu Wang
Publikováno v:
RSC Advances. 7:14618-14624
As a new kind of two-dimensional (2D) material, black phosphorus (BP) has attracted explosive interest in biomedical applications. It is well-recognized that the biomedical performances of nanoparticles depend not only on their properties, but also o
Publikováno v:
Journal of Molecular Histology. 47:455-466
Orthodontic tooth movement (OTM) is associated with bone remodeling mediated by orthodontic mechanical loading. Increasing studies reported that Wnt signaling played crucial roles in mechanical stimuli induced bone remodeling. However, little is know
Autor:
Hao Huang, Xue-Feng Yu, Yong Li, Penghui Li, Huaiyu Wang, Chengzhang Li, Siying Tang, Beike Wang, Paul K. Chu, Zhibin Li
Publikováno v:
ACS Biomaterials Science & Engineering. 2:789-797
Gold nanorods (AuNRs) with unique plasmonic properties in the near-infrared region have promising biomedical applications but suffer from poor in vivo clearance because of the large size. In this study, small AuNRs with a diameter of 7 nm (designated
Autor:
Zhibin Li, Chengzhang Li, Penghui Li, Paul K. Chu, Xue-Feng Yu, Huaiyu Wang, Beike Wang, Jiahong Wang, Li Song
Publikováno v:
Biomaterials. 78:27-39
Nanomaterials-mediated photothermal therapy (PTT) often suffers from the fundamental cellular defense mechanism of heat shock response which leads to therapeutic resistance of cancer cells and reduces the therapeutic efficacy. Herein, a gold nanorods