Zobrazeno 1 - 10
of 1 491
pro vyhledávání: '"Beijersbergen, A."'
Autor:
Abalo, L., Kretschmar, P., Fürst, F., Diez, C. M., Mellah, I. El, Grinberg, V., Guainazzi, M., Martínez-Núñez, S., Manousakis, A., Amato, R., Zhou, M., Beijersbergen, M. W.
Publikováno v:
A&A 692, A188 (2024)
Strong stellar winds are an important feature in wind-accreting high-mass X-ray binary (HMXB) systems, providing insights into stellar evolution and their impact on surrounding environments. However, the long-term evolution and temporal variability o
Externí odkaz:
http://arxiv.org/abs/2410.21456
Autor:
Xabier Vergara, Anna G. Manjón, Marcel de Haas, Ben Morris, Ruben Schep, Christ Leemans, Anoek Friskes, Roderick L. Beijersbergen, Mathijs A. Sanders, René H. Medema, Bas van Steensel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract DNA double-strand breaks are repaired by multiple pathways, including non-homologous end-joining (NHEJ) and microhomology-mediated end-joining (MMEJ). The balance of these pathways is dependent on the local chromatin context, but the underly
Externí odkaz:
https://doaj.org/article/6009cbab086a43759a3f31b9c33c7f5d
Autor:
Dopler, Anna, Alkan, Ferhat, Malka, Yuval, van der Kammen, Rob, Hoefakker, Kelly, Taranto, Daniel, Kocabay, Naz, Mimpen, Iris, Ramirez, Christel, Malzer, Elke, Isaeva, Olga I., Kerkhoff, Mandy, Gangaev, Anastasia, Silva, Joana, Ramalho, Sofia, Hoekman, Liesbeth, Altelaar, Maarten, Beijersbergen, Roderick, Akkari, Leila, Yewdell, Jonathan Wilson, Kvistborg, Pia, Faller, William James
Publikováno v:
In Cell 27 November 2024 187(24):6981-6993
Autor:
Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, Maliha Wajahat, Amy R Dwyer, Isabel Mayayo‐Peralta, Gabriela Gomez, Maarten Altelaar, Roderick Beijersbergen, Balázs Győrffy, Leonie Young, Sabine Linn, Jos Jonkers, Wayne Tilley, Theresa Hickey, Damir Vareslija, Alexander Swarbrick, Wilbert Zwart
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-17 (2023)
Abstract Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate that GR relates to the proliferative capacity of nume
Externí odkaz:
https://doaj.org/article/7f89e9b972df425581429cdb0b5d1a09
Autor:
Chen, Mengnuo, Mainardi, Sara, Lieftink, Cor, Velds, Arno, de Rink, Iris, Yang, Chen, Kuiken, Hendrik J., Morris, Ben, Edwards, Finn, Jochems, Fleur, van Tellingen, Olaf, Boeije, Manon, Proost, Natalie, Jansen, Robin A., Qin, Shifan, Jin, Haojie, Koen van der Mijn, J.C., Schepers, Arnout, Venkatesan, Subramanian, Qin, Wenxin, Beijersbergen, Roderick L., Wang, Liqin, Bernards, René
Publikováno v:
In Cell Reports Medicine 19 March 2024 5(3)
Autor:
Antonio Mulero‐Sánchez, Christel F. A. Ramirez, Aimée duChatinier, Hui Wang, Sofie J. I. Koomen, Ji‐Ying Song, Marnix H. P. deGroot, Cor Lieftink, Astrid Bosma, Artur Burylo, Olaf vanTellingen, Roderick L. Beijersbergen, Cun Wang, Leila Akkari, René Bernards, Sara Mainardi
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 964-980 (2023)
Liver cancer is the fourth most common cause of cancer‐related death worldwide, with hepatocellular carcinoma (HCC) being the main primary malignancy affecting the liver. Unfortunately, there are still limited therapeutic options for HCC, and even
Externí odkaz:
https://doaj.org/article/127c0b27e58a4e90916c39f950995ed1
Autor:
Vera E. van der Noord, Wanda van der Stel, Gijs Louwerens, Danielle Verhoeven, Hendrik J. Kuiken, Cor Lieftink, Melanie Grandits, Gerhard F. Ecker, Roderick L. Beijersbergen, Peter Bouwman, Sylvia E. Le Dévédec, Bob van de Water
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-20 (2023)
Abstract Background Triple-negative breast cancer (TNBC) is a subtype of breast cancer with limited treatment options and poor clinical prognosis. Inhibitors of transcriptional CDKs are currently under thorough investigation for application in the tr
Externí odkaz:
https://doaj.org/article/3cd3539eec0948958a3e708b71d4da89
Autor:
van Breugel, Maria Elize, van Kruijsbergen, Ila, Mittal, Chitvan, Lieftink, Cor, Brouwer, Ineke, van den Brand, Teun, Kluin, Roelof J.C., Hoekman, Liesbeth, Menezes, Renée X., van Welsem, Tibor, Del Cortona, Andrea, Malik, Muddassir, Beijersbergen, Roderick L., Lenstra, Tineke L., Verstrepen, Kevin J., Pugh, B. Franklin, van Leeuwen, Fred
Publikováno v:
In Molecular Cell 7 December 2023 83(23):4205-4221
Autor:
Joyce Y. Buikhuisen, Patricia M. Gomez Barila, Kate Cameron, Saskia J. E. Suijkerbuijk, Cor Lieftink, Simone di Franco, Ana Krotenberg Garcia, Rebeca Uceda Castro, Kristiaan J. Lenos, Lisanne E. Nijman, Arezo Torang, Ciro Longobardi, Joan H. de Jong, Daniëlle Dekker, Giorgio Stassi, Louis Vermeulen, Roderick L. Beijersbergen, Jacco van Rheenen, Stephan Huveneers, Jan Paul Medema
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Colorectal cancer (CRC) can be divided into four consensus molecular subtypes (CMS), each with distinct biological features. CMS4 is associated with epithelial-mesenchymal transition and stromal infiltration (Guinney et al., Nat M
Externí odkaz:
https://doaj.org/article/f5507e6ca1b2488d88586c36a3b6eee2
Autor:
Bhin, Jinhyuk, Paes Dias, Mariana, Gogola, Ewa, Rolfs, Frank, Piersma, Sander R., de Bruijn, Roebi, de Ruiter, Julian R., van den Broek, Bram, Duarte, Alexandra A., Sol, Wendy, van der Heijden, Ingrid, Andronikou, Christina, Kaiponen, Taina S., Bakker, Lara, Lieftink, Cor, Morris, Ben, Beijersbergen, Roderick L., van de Ven, Marieke, Jimenez, Connie R., Wessels, Lodewyk F.A., Rottenberg, Sven, Jonkers, Jos
Publikováno v:
In Cell Reports 30 May 2023 42(5)