Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Beihua Xu"'
Autor:
Beihua Xu, Zhenyu Wang, Huimin Zhang, Xiao Xu, Mengjie Tang, Gang Wang, Zhongpeng Ding, Ruihao Yu, Meihong Ding, Ting Zhang, Senlin Shi
Publikováno v:
Molecules, Vol 29, Iss 17, p 4073 (2024)
Objective: The aim of this study was to optimize the formulation of a C60-modified self-microemulsifying drug delivery system loaded with triptolide (C60-SMEDDS/TP) and evaluate the cytoprotective effect of the C60-SMEDDS/TP on normal human cells. Re
Externí odkaz:
https://doaj.org/article/3d0147ce08bc471f895a40e06d341e57
Autor:
Zhongpeng Ding, Beihua Xu, Huimin Zhang, Zhenyu Wang, Luying Sun, Mengjie Tang, Meihong Ding, Ting Zhang, Senlin Shi
Publikováno v:
Molecules, Vol 28, Iss 22, p 7609 (2023)
Objective: The objective of this study was to examine the preparation process of DSPE-PEG-C60/NCTD micelles and assess the impact of fullerenol (C60)-modified micelles on the nephrotoxicity and antitumor activity of NCTD. Method: The micelles contain
Externí odkaz:
https://doaj.org/article/e6fed45979764541817f907ce8c9201a
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
To deliver doxorubicin (DOX) with enhanced efficacy and safety in vivo, fullerenol-modified micelles were prepared with the amphiphilic polymer DSPE-PEG-C60 as a carrier, which was synthesized by linking C60(OH)22 with DSPE-PEG-NH2. Studies of its pa
Externí odkaz:
https://doaj.org/article/328cee3785414892810fd8ab020ac479
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Doxorubicin (DOX) is one of the most commonly used chemotherapeutic agents for treating human cancer. However, its clinical use has been limited by DOX-induced cardiotoxicity as well as other side effects. In the present study, we designed and synthe
Externí odkaz:
https://doaj.org/article/5a0b73c1d9d14b79856c1b2857f09647
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The mutations and deregulation of Wnt signaling pathway occur commonly in human cancer and cause the aberrant activation of β-catenin and β-catenin-dependent transcription, thus contributing to cancer development and progression. Therefore, β-cate
Externí odkaz:
https://doaj.org/article/eceb6f90dfd94bcc9a3cb9747f2dc6d4
Autor:
Jia Zhang, Weiyi Wang, Yuan Zhou, Jing Yang, Jingli Xu, Zhiyuan Xu, Beihua Xu, Li Yan, Xiang-Dong Cheng, Minghua Li, Jiang-Jiang Qin
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Pancreatic cancer (PC) is an aggressive and fatal disease with high incidences of metastasis and recurrence. However, there are no effective treatment options for the majority of PC patients, especially for those with locally advanced tumors and meta
Externí odkaz:
https://doaj.org/article/26dd68fffaa747ba89fa1a29c030ac55
Autor:
Si-Min Qi, Gang Cheng, Xiang-Dong Cheng, Zhiyuan Xu, Beihua Xu, Wei-Dong Zhang, Jiang-Jiang Qin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The p53 tumor suppressor protein and its major negative regulators MDM2 and MDMX oncoproteins form the MDM2/MDMX-p53 circuitry, which plays critical roles in regulating cancer cell growth, proliferation, cell cycle progression, apoptosis, senescence,
Externí odkaz:
https://doaj.org/article/a3eab85d16dd408d9fff6c7d48c5edc9
Publikováno v:
Advances in Skin & Wound Care. 36:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61752b63e6e97e51252d5d7aff351b27
https://doi.org/10.1097/01.asw.0000920512.88426.90
https://doi.org/10.1097/01.asw.0000920512.88426.90
Publikováno v:
Drug development and industrial pharmacy. 47(11)
Melanoma accounts for the highest proportion of all skin cancer deaths. Immune-chemotherapy has transformed anti-melanoma therapy and is a preferred first-line combination strategy for melanoma. We previously prepared dendritic cells (DCs) targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c077ce24b7da53c6923994ae6a59607
https://pubmed.ncbi.nlm.nih.gov/35193436
https://pubmed.ncbi.nlm.nih.gov/35193436
Publikováno v:
WCET Journal. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007deac389c8588ea245bb0dda239fec
https://doi.org/10.33235/wcet.41.1.16-20
https://doi.org/10.33235/wcet.41.1.16-20