Zobrazeno 1 - 10
of 594
pro vyhledávání: '"Beige adipocyte"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Obesity is increasing globally and is closely associated with a range of metabolic disorders, including metabolic associated fatty liver disease, diabetes, and cardiovascular diseases. An effective strategy to combat obesity involves stimulating brow
Externí odkaz:
https://doaj.org/article/c6f2b07c10754310bb6e526fd350d2eb
Publikováno v:
Adipocyte, Vol 13, Iss 1 (2024)
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism. In mice, BAT quickly stimulates thermogenesis by activating brown adipocytes upon cold
Externí odkaz:
https://doaj.org/article/888ba272eed148ed8150289f0ea7ffb7
Autor:
Mahdokht Mahmoodi, Elahe Mirzarazi Dahagi, Mir‐Hamed Nabavi, Ylauna C. M. Penalva, Amrita Gosaine, Monzur Murshed, Sandrine Couldwell, Lisa M. Munter, Mari T. Kaartinen
Publikováno v:
Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)
Abstract Plasma fibronectin (pFN) is a hepatocyte‐derived circulating extracellular matrix protein that affects cell morphology, adipogenesis, and insulin signaling of adipocytes in vitro. In this study, we show pFN accrual to adipose tissue and it
Externí odkaz:
https://doaj.org/article/98eab24d4b3746e0a419bb46aede5a2e
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe beneficial effect of thermogenic adipocytes in maintaining body weight and protecting against metabolic disorders has raised interest in understanding the regulatory mechanisms defining white and beige adipocyte identity. Although alter
Externí odkaz:
https://doaj.org/article/4226de2cf38b407393d01b6cf67206a2
Autor:
Corey D Holman, Alexander P Sakers, Ryan P Calhoun, Lan Cheng, Ethan C Fein, Christopher Jacobs, Linus Tsai, Evan D Rosen, Patrick Seale
Publikováno v:
eLife, Vol 12 (2024)
The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte
Externí odkaz:
https://doaj.org/article/a87d04754b664275933a128e3f2ac78b
Autor:
Raja Gopal Reddy Mooli, Bokai Zhu, Saifur R. Khan, Veerababu Nagati, Kulandaimanuvel Antony Michealraj, Michael J. Jurczak, Sadeesh K. Ramakrishnan
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThermogenic beige adipocytes, which dissipate energy as heat, are found in neonates and adults. Recent studies show that neonatal beige adipocytes are highly plastic and contribute to >50% of beige adipocytes in adults. Neonatal beige adipo
Externí odkaz:
https://doaj.org/article/c67b53bffb8a42d4b4b60b741db8cbda
Publikováno v:
eLife, Vol 13 (2024)
Perirenal adipose tissue (PRAT) is a unique visceral depot that contains a mixture of brown and white adipocytes. The origin and plasticity of such cellular heterogeneity remains unknown. Here, we combine single-nucleus RNA sequencing with genetic li
Externí odkaz:
https://doaj.org/article/31f30b9ec13d4d74b221cd05436b8dac
Autor:
Magdalena Kotańska, Monika Zadrożna, Monika Kubacka, Kamil Mika, Katarzyna Szczepańska, Barbara Nowak, Alessio Alesci, Anthea Miller, Eugenia Rita Lauriano, Katarzyna Kieć-Kononowicz
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 858 (2024)
Background: Numerous studies highlight the critical role that neural histamine plays in feeding behavior, which is controlled by central histamine H3 and H1 receptors. This is the fundamental motivation for the increased interest in creating histamin
Externí odkaz:
https://doaj.org/article/a89f1fff18ba46f69f8f2291d9821f40
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1474 (2024)
Obesity is a complex medical condition caused by a positive imbalance between calorie intake and calorie consumption. Brown adipose tissue (BAT), along with the newly discovered “brown-like” adipocytes (called beige cells), functions as a promisi
Externí odkaz:
https://doaj.org/article/3364c799ad8542d49f4b90804d525488
Autor:
Choijamts Munkhzul, Ji-Min Lee, Boseon Kim, Thi Thanh My Nguyen, Rehna Paula Ginting, Dahee Jeong, Young-Kook Kim, Min-Woo Lee, Mihye Lee
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Adipose tissue, an organ critical for systemic energy homeostasis, is influenced by type 2 immunity in its development and function. The type 2 cytokine interleukin (IL)-4 induces the proliferation of bipotential adipocyte precursors (APs) i
Externí odkaz:
https://doaj.org/article/d3dbbfb4d1e448ad99e08224d17207d8