Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Beifen, Shen"'
Autor:
Kaitong Li, Junyu Cai, Zhiyang Jiang, Qingbin Meng, Zhao Meng, He Xiao, Guojiang Chen, Chunxia Qiao, Longlong Luo, Jijun Yu, Xinying Li, Yinxiang Wei, Hui Li, Chenghua Liu, Beifen Shen, Jing Wang, Jiannan Feng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The cytokine interleukin-6 (IL-6) plays a crucial role in autoimmune and inflammatory diseases. Understanding the precise mechanism of IL-6 interaction at the amino acid level is essential to develop IL-6-inhibiting compounds. In this study,
Externí odkaz:
https://doaj.org/article/8b8607240b5b47789e2022b4e902b64b
Autor:
Rongrong Fan, Zeliang Wei, Mengmeng Zhang, Shanshan Jia, Zhiyang Jiang, Yao Wang, Junyu Cai, Guojiang Chen, He Xiao, Yinxiang Wei, Yanchun Shi, Jiannan Feng, Beifen Shen, Yuanqiang Zheng, Yaojiang Huang, Jing Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCD2v, a critical outer envelope glycoprotein of the African swine fever virus (ASFV), plays a central role in the hemadsorption phenomenon during ASFV infection and is recognized as an essential immunoprotective protein. Monoclonal antibodi
Externí odkaz:
https://doaj.org/article/4af87011c9774c63bccd03eeccf84c28
Autor:
Nan Chen, Renxi Wang, Wanlu Zhu, Xiangjun Hao, Jing Wang, Guojiang Chen, ChunXia Qiao, Xinying Li, Chenghua Liu, Beifen Shen, Jiannan Feng, Lihui Chai, Zuyin Yu, He Xiao
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302865 (2024)
Influenza A viruses (IAVs) continue to pose a huge threat to public health, and their prevention and treatment remain major international issues. Neuraminidase (NA) is the second most abundant surface glycoprotein on influenza viruses, and antibodies
Externí odkaz:
https://doaj.org/article/7544374129ad40b1ba754f2da9e2b606
Autor:
Yonggen Jia, Zhangchun Guan, Chenghua Liu, Minjun Huang, Jingjing Li, Jiannan Feng, Beifen Shen, Guang Yang
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Staphylococcus aureus is a common cause of inflammatory skin diseases, with one of its virulence factors, β-hemolysin (Hlb), known to promote skin colonization. However, its direct involvement in skin inflammation is unclear. In this study,
Externí odkaz:
https://doaj.org/article/08a641be4d214e26ae554bcbe9932490
Autor:
Fenghao Peng, Naijing Hu, Yingjun Liu, Cong Xing, Longlong Luo, Xinying Li, Jing Wang, Guojiang Chen, He Xiao, Chenghua Liu, Beifen Shen, Jiannan Feng, Chunxia Qiao
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health. Smallpox was declared eradicated in 1980, and Many countries
Externí odkaz:
https://doaj.org/article/07b185b063c5457996a003f807ee740c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The continuous mutation of SARS-CoV-2 has presented enormous challenges to global pandemic prevention and control. Recent studies have shown evidence that the genome sequence of SARS-CoV-2 nucleocapsid proteins is relatively conserved, and t
Externí odkaz:
https://doaj.org/article/bb615d0c31584898b40abdd2342883c8
Autor:
Hao Liu, Chunxia Qiao, Naijing Hu, Zhihong Wang, Jing Wang, Jiannan Feng, Beifen Shen, Yuanfang Ma, Longlong Luo
Publikováno v:
Engineering, Vol 7, Iss 11, Pp 1557-1565 (2021)
Immunotherapy with anti-programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) monoclonal antibodies has become routine in the treatment of many kinds of human cancers, such as lung cancer, intestinal cancer, and melanoma. The
Externí odkaz:
https://doaj.org/article/b25248d9110d4919acbac2b0f7e04cde
Autor:
Chunxia Qiao, Ming Lv, Xinying Li, Xiaoling Lang, Shouqin Lv, Mian Long, Yan Li, Shusheng Geng, Zhou Lin, Beifen Shen, Jiannan Feng
Publikováno v:
Engineering, Vol 7, Iss 11, Pp 1566-1576 (2021)
Fully human antibodies have minimal immunogenicity and safety profiles. At present, most potential antibody drugs in clinical trials are humanized or fully human. Human antibodies are mostly generated using the phage display method (in vitro) or by t
Externí odkaz:
https://doaj.org/article/e70c033ea5d74155a0ed00602f742efe
Autor:
Jijun Yu, Luoxuan Wang, Xiangya Kong, Yang Cao, Mengmeng Zhang, Zhaolin Sun, Yang Liu, Jing Wang, Beifen Shen, Xiaochen Bo, Jiannan Feng
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cancer vaccines have gradually attracted attention for their tremendous preclinical and clinical performance. With the development of next-generation sequencing technologies and related algorithms, pipelines based on sequencing and machine learning m
Externí odkaz:
https://doaj.org/article/c2cfb449e0734c26b728fbcc780baf95
Autor:
Lili Tang, Ge Li, Yang Zheng, Chunmei Hou, Yang Gao, Ying Hao, Zhenfang Gao, Rongliang Mo, Yuxiang Li, Beifen Shen, Renxi Wang, Zhiding Wang, Gencheng Han
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Tim-3, an immune checkpoint inhibitor, is widely expressed on the immune cells and contributes to immune tolerance. However, the mechanisms by which Tim-3 induces immune tolerance remain to be determined. Major histocompatibility complex II (MHC-II)
Externí odkaz:
https://doaj.org/article/1fc208dae2f246b4ba2a05de10a55876