Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Beierschmitt, A."'
Akademický článek
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Autor:
Brian V Tsu, Rimjhim Agarwal, Nandan S Gokhale, Jessie Kulsuptrakul, Andrew P Ryan, Elizabeth J Fay, Lennice K Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A Turcotte, Sofia E Delgado-Rodriguez, Russell E Vance, Jennifer L Hyde, Ram Savan, Patrick S Mitchell, Matthew D Daugherty
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002144 (2023)
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL protease (3CLpro) encoded by diverse c
Externí odkaz:
https://doaj.org/article/cdf5043f3dfb4817b3329b51ef3b0db4
Akademický článek
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Autor:
Donté Alexander Stevens, Christopher Beierschmitt, Swetha Mahesula, Miles R Corley, John Salogiannis, Brian V Tsu, Bryant Cao, Andrew P Ryan, Hiroyuki Hakozawki, Samara L Reck-Peterson, Matthew D Daugherty
Publikováno v:
eLife, Vol 11 (2022)
Viruses interact with the intracellular transport machinery to promote viral replication. Such host–virus interactions can drive host gene adaptation, leaving signatures of pathogen-driven evolution in host genomes. Here, we leverage these genetic
Externí odkaz:
https://doaj.org/article/e59611f3ae034a729149b9fc1746e00b
Autor:
Diana M. Mancuso, Kerry Gainor, Kerry M. Dore, Christa A. Gallagher, Katalina Cruz, Amy Beierschmitt, Yashpal S. Malik, Souvik Ghosh
Publikováno v:
Viruses, Vol 15, Iss 7, p 1605 (2023)
In the present study, 31 samples (12 fecal, 9 nasal and 10 rectal swabs) from 28/92 (30.43%, 10 captive and 18 free-roaming African green monkeys (AGMs, Chlorocebus sabaeus)) apparently healthy AGMs in the Caribbean Island of St. Kitts tested positiv
Externí odkaz:
https://doaj.org/article/e3719cc2cd72467991047e2a8f93cf86
Akademický článek
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Autor:
Matthew John Valentine, Brenda Ciraola, Matthew Thomas Aliota, Michel Vandenplas, Silvia Marchi, Bernard Tenebray, Isabelle Leparc-Goffart, Christa Ann Gallagher, Amy Beierschmitt, Tatiana Corey, Kerry McAuliffe Dore, Xavier de Lamballerie, Chengming Wang, Courtney Cuin Murdock, Patrick John Kelly
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background Dengue, chikungunya and Zika viruses (DENV, CHIKV and ZIKV) are transmitted in sylvatic transmission cycles between non-human primates and forest (sylvan) mosquitoes in Africa and Asia. It remains unclear if sylvatic cycles exist
Externí odkaz:
https://doaj.org/article/17b081b5522443768a6f05b365ef58b7
Autor:
Katrina T. Nguyen, Joseph Sugie, Kanika Khanna, MacKennon E. Egan, Erica A. Birkholz, Jina Lee, Christopher Beierschmitt, Elizabeth Villa, Joe Pogliano
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
Upon infection of Pseudomonas cells, jumbo phages 201Φ2–1, ΦPA3, and ΦKZ assemble a phage nucleus. Viral DNA is enclosed within the phage-encoded proteinaceous shell along with proteins associated with DNA replication, recombination and transcri
Externí odkaz:
https://doaj.org/article/c3817c374adc490c965a15ffda57b35d
Autor:
Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty
Publikováno v:
eLife, Vol 10 (2021)
The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains
Externí odkaz:
https://doaj.org/article/4a963c5b452f4d9c88a2a2ddfa16fdf1
Autor:
Pål Trosvik, Eric J. de Muinck, Eli K. Rueness, Peter J. Fashing, Evan C. Beierschmitt, Kadie R. Callingham, Jacob B. Kraus, Thomas H. Trew, Amera Moges, Addisu Mekonnen, Vivek V. Venkataraman, Nga Nguyen
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-18 (2018)
Abstract Background The gelada monkey (Theropithecus gelada), endemic to the Ethiopian highlands, is the only graminivorous primate, i.e., it feeds mainly on grasses and sedges. In spite of known dental, manual, and locomotor adaptations, the intesti
Externí odkaz:
https://doaj.org/article/c6af7cd5341b4eb5a3dfde721faf5427