Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Beibei Yu"'
Autor:
Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong
Publikováno v:
Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-19 (2025)
Abstract Background Spinal cord injury (SCI) triggers a complex inflammatory response that impedes neural repair and functional recovery. The modulation of macrophage phenotypes is thus considered a promising therapeutic strategy to mitigate inflamma
Externí odkaz:
https://doaj.org/article/4441df6e1ab7428e8b20d4afd6b22bf1
Publikováno v:
FEBS Open Bio, Vol 14, Iss 12, Pp 2104-2112 (2024)
The activity of Hippo signaling is commonly dysregulated in various human malignancies, including hepatocellular carcinoma (HCC). YAP, the key effector of Hippo pathway, is regulated through several posttranslational modifications. However, the mecha
Externí odkaz:
https://doaj.org/article/2499e3e073464b4bb44a080863896478
Autor:
Borui Xue, Yan Peng, Yongfeng Zhang, Shijie Yang, Yi Zheng, Huiling Hu, Xueli Gao, Beibei Yu, Xue Gao, Shengyou Li, Haining Wu, Teng Ma, Yiming Hao, Yitao Wei, Lingli Guo, Yujie Yang, Zhenguo Wang, Tingfeng Xue, Jin Zhang, Beier Luo, Bing Xia, Jinghui Huang
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract In situ disc regeneration is a meticulously orchestrated process, which involves cell recruitment, proliferation and differentiation within a local inflammatory niche. Thus far, it remains a challenge to establish a multi‐staged regulatory
Externí odkaz:
https://doaj.org/article/4cfdc4f99784404aa62c4757ac84bef4
Autor:
Changping Xu, Zhengyang Wang, Beibei Yu, Zhenhuang Pan, Jun Ni, Yan Feng, Shiwang Huang, Maomao Wu, Jiancang Zhou, Lei Fang, Zhiwei Wu
Publikováno v:
Virus Research, Vol 346, Iss , Pp 199410- (2024)
Here we report an ultrafast quadruplex RT-qPCR assay with robust diagnostic ability to detect and distinguish pan-SARS-CoVs and influenza A/B viruses within 35 min. This quadruplex RT-qPCR assay comprised of one novel RNA-based internal control targe
Externí odkaz:
https://doaj.org/article/c9882d3f9ab349c2a8e5b741505150bc
Autor:
Yanqun Wang, An Yan, Deyong Song, Maoqin Duan, Chuangchuang Dong, Jiantao Chen, Zihe Jiang, Yuanzhu Gao, Muding Rao, Jianxia Feng, Zhaoyong Zhang, Ruxi Qi, Xiaomin Ma, Hong Liu, Beibei Yu, Qiaoping Wang, Mengqi Zong, Jie Jiao, Pingping Xing, Rongrong Pan, Dan Li, Juxue Xiao, Junbo Sun, Ying Li, Linfeng Zhang, Zhenduo Shen, Baiping Sun, Yanyan Zhao, Lu Zhang, Jun Dai, Jingxian Zhao, Lan Wang, Changlin Dou, Zheng Liu, Jincun Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The constant emergence of SARS-CoV-2 variants continues to impair the efficacy of existing neutralizing antibodies, especially XBB.1.5 and EG.5, which showed exceptional immune evasion properties. Here, we identify a highly conserved neutral
Externí odkaz:
https://doaj.org/article/c33908424c5646a8b6688faee41eaca1
Autor:
Changping Xu, Yalin Chen, Guiying Zhu, Huan Wu, Qi Jiang, Rui Zhang, Beibei Yu, Lei Fang, Zhiwei Wu
Publikováno v:
Micromachines, Vol 15, Iss 5, p 663 (2024)
Chikungunya virus, a mosquito-borne virus that causes epidemics, is often misdiagnosed due to symptom similarities with other arboviruses. Here, a portable and integrated nucleic acid-based diagnostic device, which combines reverse transcription-loop
Externí odkaz:
https://doaj.org/article/399e5847ca994be59a45063fb8afceca
Autor:
Xue Gao, Shengyou Li, Yujie Yang, Shijie Yang, Beibei Yu, Zhijie Zhu, Teng Ma, Yi Zheng, Bin Wei, Yiming Hao, Haining Wu, Yongfeng Zhang, Lingli Guo, Xueli Gao, Yitao Wei, Borui Xue, Jianzhong Li, Xue Feng, Lei Lu, Bing Xia, Jinghui Huang
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Addressing the challenge of promoting directional axonal regeneration in a hostile astrocytic scar, which often impedes recovery following spinal cord injury (SCI), remains a daunting task. Cell transplantation is a promising strategy to fac
Externí odkaz:
https://doaj.org/article/84ded7be6f72463eb04a09287afa5d8d
Autor:
Yanqun Wang, An Yan, Deyong Song, Chuangchuang Dong, Muding Rao, Yuanzhu Gao, Ruxi Qi, Xiaomin Ma, Qiaoping Wang, Hongguang Xu, Hong Liu, Jing Han, Maoqin Duan, Shuo Liu, Xiaoping Yu, Mengqi Zong, Jianxia Feng, Jie Jiao, Huimin Zhang, Min Li, Beibei Yu, Yanxia Wang, Fanhao Meng, Xiaodan Ni, Ying Li, Zhenduo Shen, Baiping Sun, Xin Shao, Haifeng Zhao, Yanyan Zhao, Rui Li, Yanan Zhang, Guangying Du, Jun Lu, Chunna You, Hua Jiang, Lu Zhang, Lan Wang, Changlin Dou, Zheng Liu, Jincun Zhao
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract SARS-CoV-2 Omicron subvariants have demonstrated extensive evasion from monoclonal antibodies (mAbs) developed for clinical use, which raises an urgent need to develop new broad-spectrum mAbs. Here, we report the isolation and analysis of tw
Externí odkaz:
https://doaj.org/article/b38531d441f14db695079f6108b97685
Autor:
Lei Xu, Chuan Wei, Ying Chen, Yue Wu, Xiaoli Shou, Wenjie Chen, Di Lu, Haoran Sun, Wei Li, Beibei Yu, Xiaowei Wang, Xiaojun Zhang, Yanxiong Yu, Zhigang Lei, Rui Tang, Jifeng Zhu, Yalin Li, Linrong Lu, Hong Zhou, Sha Zhou, Chuan Su, Xiaojun Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Immunosuppression as a result of severe infection impairs pathogen clearance and can increase susceptibility to secondary infection. Here, the authors dissect how T cell aging and the thymic involution that occurs during this process contribute to im
Externí odkaz:
https://doaj.org/article/2f433d2465024893b4832e8b16fd1980
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Ovarian function influences diverse aspects of fertility and reproductive lifespan by regulating oocyte supply and hormone secretion. Lysine crotonylation (Kcr) and lysine 2-hydroxyisobutyryllysine (Khib) are newly identified post-translational modif
Externí odkaz:
https://doaj.org/article/d586ae18a45d4375abc99583467640f2