Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Beibei Liang"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The global elderly population is on the rise, and infections tend to have a higher mortality rate among older individuals. Aging is associated with the progressive impairment of multi-organ function, which can impact the pharmacokinetics of antimicro
Externí odkaz:
https://doaj.org/article/401c1f207722413091225b5526baaf68
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 428-433 (2024)
Goal: The purpose of this paper is to recognize autism spectrum disorders (ASD) using graph attention network. Methods: we propose a node features graph attention network (NF-GAT) for learning functional connectivity (FC) features to achieve ASD diag
Externí odkaz:
https://doaj.org/article/42110df3d4ad4889b45d401d4b37aa43
Publikováno v:
Neurology and Therapy, Vol 12, Iss 3, Pp 947-959 (2023)
Abstract Introduction To assess the safety, tolerability and pharmacokinetics of a single dose of SYHA1402 in healthy Chinese subjects. Methods This was a randomized, double-blind, placebo-controlled, single-ascending dose study in healthy subjects.
Externí odkaz:
https://doaj.org/article/6c8eea81a1314965b2541ffa99cc4717
Autor:
Qiqi Tang, Beibei Liang, Lisha Zhang, Xuhui Li, Hengyu Li, Wei Jing, Yingjie Jiang, Felix Zhou, Jian Zhang, Yanchun Meng, Xinhua Yang, Hao Yang, Gang Huang, Jian Zhao
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Neutrophil extracellular traps (NETs) has been demonstrated to regulate the metastasis of breast cancer. In this study, we showed that de novo cholesterol biosynthesis induced by ASPP2 depletion in mouse breast cancer cell 4T1 and human brea
Externí odkaz:
https://doaj.org/article/345421f0d0b341149f363081fa807c3a
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 29, Iss , Pp 88-96 (2022)
ABSTRACT: Objectives: Since the gene encoding mobilised colistin resistance (mcr-1) was first reported in China in 2015, it has been reported in various Enterobacteriaceae worldwide. Escherichia coli, one of the main pathogens causing diarrhoea, is t
Externí odkaz:
https://doaj.org/article/0de0abc402e9421b89b3d0f8d64ea841
Autor:
Kaijie Chen, Beibei Liang, Wenhao Ma, Guoqing Wan, Bing Chen, Changlian Lu, Yuzhou Luo, Xuefeng Gu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Metformin is widely used in the treatment of type 2 diabetes (T2D) and plays a role in antitumor and antiobesity processes. A recent study identified its direct molecular target, PEN2 (PSENEN). PSENEN is the minimal subunit of the multiprotein comple
Externí odkaz:
https://doaj.org/article/a4e0614c7810431a85138bb51090f37e
Autor:
Nian Dong, Yongrui Li, Jiayong Zhao, Hui Ma, Jinyan Wang, Beibei Liang, Xinying Du, Fuli Wu, Shengli Xia, Xiaoxia Yang, Hongbo Liu, Chaojie Yang, Shaofu Qiu, Hongbin Song, Leili Jia, Yan Li, Yansong Sun
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Salmonella enterica subsp. enterica serovar Typhimurium infections continue to be a significant public health threat worldwide. The aim of this study was to investigate antibiotic resistance among 147 S. Typhimurium isolates colle
Externí odkaz:
https://doaj.org/article/69fc4632240d43fd9b8f9d3c1171bb8e
Autor:
Haoran Zhang, Ying Xiang, Yong Huang, Beibei Liang, Xuebin Xu, Jing Xie, Xinying Du, Chaojie Yang, Hongbo Liu, Hui Wang, Mingjuan Yang, Ligui Wang, Xiaofeng Hu, Lianqun Jin, Jinsong Li, Yongqiang Jiang, Shaofu Qiu, Hongbin Song
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
With the rapid emergence of plasmid-mediated colistin resistance gene mcr-1, the increased resistance of Salmonella has attracted extensive attention. This study reports on 11 multidrug-resistant Salmonella enterica serovar Typhimurium strains harbor
Externí odkaz:
https://doaj.org/article/4749007af4304276bcccd1be64d594d3
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 213 (2023)
Immunotherapy blocking programmed cell death protein 1/programmed death ligand 1 (PD-1/PD-L1) pathway has achieved great therapeutic effect in the clinic, but the overall response rate is not satisfactory. Early studies showed that response to treatm
Externí odkaz:
https://doaj.org/article/a0be3c1591cf4b19b8a961440ae33b23
Autor:
Beibei Liang, Shiguo Wan, Qingling Ma, Li Yang, Wei Hu, Liuqing Kuang, Jingheng Xie, Yingjie Huang, Dechun Liu, Yong Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15053 (2022)
Drought limits citrus yield and fruit quality worldwide. The basic helix-loop-helix (bHLH) transcription factors (TFs) are involved in plant response to drought stress. However, few bHLH TFs related to drought response have been functionally characte
Externí odkaz:
https://doaj.org/article/7b36be4f388d49a687fa82d231d72faa