Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bei-Bei Huang"'
Autor:
Meng-Ran Zhang, Hong-Guang Xie, Yu-Meng Jia, Huan Zhou, Qiong-Yu Mi, Ting Tai, Bei-Bei Huang, Jin-Zi Ji, Tong-Tong Gu
Publikováno v:
Biopharmaceutics & Drug Disposition. 39:88-98
Clopidogrel is predominantly hydrolyzed to clopidogrel carboxylic acid (CCA) by carboxylesterase 1, and subsequently CCA is glucuronidated to clopidogrel acyl glucuronide (CAG) by uridine diphosphate-glucuronosyltransferases (UGTs); however, the UGT
Autor:
Ting Zhu, Hong-Guang Xie, Qiong-Yu Mi, Yi-Fei Li, Jin-Zi Ji, Bei-Bei Huang, Tong-Tong Gu, Huan Zhou, Ting Tai, Yu-Meng Jia, Peng-Xin Ge
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 115, Iss, Pp-(2019)
Both aspirin and vicagrel are effective antiplatelet drugs, with the potential for concomitant use as another dual-antiplatelet therapy for the prevention of recurrent thrombotic or ischemic events. Because they both are the substrates of carboxylest
Enhanced Platelet Response to Clopidogrel in Abcc3-deficient Mice Due to Its Increased Bioactivation
Autor:
Hong-Guang Xie, Meng-Ran Zhang, Qiong-Yu Mi, Ting Tai, Pan Yuqin, Yin Qian, Bei-Bei Huang, Jin-Zi Ji
Publikováno v:
Journal of Cardiovascular Pharmacology. 68:433-440
Resistance of the patient to clopidogrel (an inactive prodrug) has been recently reported to be associated with increased messenger RNA expression of ABCC3 that encodes MRP3 (multidrug resistance-associated protein 3). However, there is no evidence s
Autor:
Hong-Guang Xie, Meng-Ran Zhang, Yu-Meng Jia, Bei-Bei Huang, Huan Zhou, Qiong-Yu Mi, Ting Tai, Jin-Zi Ji, Tong-Tong Gu
Publikováno v:
Journal of cardiovascular pharmacology. 72(5)
Vicagrel, a novel acetate analogue of clopidogrel, exerts more potent antiplatelet effect than clopidogrel in rodents. Relevant evidence indicated that aspirin and vicagrel are the drug substrate for carboxylesterase 2. Accordingly, it is deduced tha
Autor:
Jin-Zi Ji, Tong-Tong Gu, Bei-Bei Huang, Yi-Fei Li, Hong-Guang Xie, Ting Zhu, Qiong-Yu Mi, Yu-Meng Jia, Ting Tai, Huan Zhou
Publikováno v:
Br J Pharmacol
Background and purpose Vicagrel is a novel promising antiplatelet drug designed for overcoming clopidogrel resistance. There is limited evidence indicating that exogenous IL-10 suppresses CYP3A4 activity in healthy subjects and that IL-10 knockout (K
Publikováno v:
World Journal of Microbiology and Biotechnology. 30:1011-1017
This present study was designed to investigate the production of huperzine A (HupA), an acetylcholine inhibitor, which was produced by an endophytic fungi isolated from Huperzia serrata. Screening of 94 endophytic fungal isolates obtained from plant
Autor:
Hai-xiao, Lu, Zhuo-ling, Wu, Wei-jiang, Liang, Mei-ling, Chen, Bei-bei, Huang, Qiao-qiao, Wei
Publikováno v:
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 38(12)
To study the chemical constituents from the roots of Semiliquidambar cathayensis.The roots of Semiliquidambar cathayensis were extracted with 80% ethanol for reflux. Chemical constituents were isolated by silica gel chromatography and Sephadex LH-20
Publikováno v:
Applied Mechanics and Materials. :1187-1196
This paper has the background of JiuJiang bridge recover engineering, and uses the approach that combining submodel method with finite element method to establish the simplified model of the whole steel-concrete composite beam bridge without consider
Publikováno v:
Surface and Interface Analysis. 40:81-84
A facile and economic method to fabricate and immobilize silver nanoparticles on a thin Si wafer (AgNP/Si) is reported for an analytical template in ambient environment by surface-enhanced infrared/Raman spectroscopy. The protocol involves immersion
Publikováno v:
Journal of Catalysis. 249:311-317
Real-time attenuated total-reflection surface-enhanced infrared absorption spectroscopy (ATR-SEIRAS), in conjunction to cyclic voltammetry, was applied to investigate the adsorption and reduction of nitric oxide at Ru electrode in acidic solutions. F