Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Behrouz Shademan"'
Autor:
Maryam Amiri, Amir Kian Moaveni, Masoumeh Majidi Zolbin, Behrouz Shademan, Alireza Nourazarian
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Optimizing cancer treatment has become a pivotal goal in modern oncology, with advancements in immunotherapy and genetic engineering offering promising avenues. CAR-T cell therapy, a revolutionary approach that harnesses the body’s own immune cells
Externí odkaz:
https://doaj.org/article/01f276c6b2ab4d508e041aa8c5af6d24
Autor:
Amir Kian Moaveni, Maryam Amiri, Behrouz Shademan, Arezoo Farhadi, Javad Behroozi, Alireza Nourazarian
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Pediatric cancers represent a tragic but also promising area for gene therapy. Although conventional treatments have improved survival rates, there is still a need for targeted and less toxic interventions. This article critically analyzes recent adv
Externí odkaz:
https://doaj.org/article/bfebc5737f774873a90bf00da2ef4e83
Autor:
Cigir Biray Avci, Bakiye Goker Bagca, Behrouz Shademan, Leila Sabour Takanlou, Maryam Sabour Takanlou, Alireza Nourazarian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cancer therapy is on the brink of a significant transformation with the inclusion of patient-derived organoids (PDOs) in drug development. These three-dimensional cell cultures, directly derived from a patient’s tumor, accurately replicate the comp
Externí odkaz:
https://doaj.org/article/19e3a26eab074868af1705be2ed26c68
Autor:
Narges Abolhasanzadeh, Sajed Sarabandi, Bahar Dehghan, Vahidreza Karamad, Cigir Biray Avci, Behrouz Shademan, Alireza Nourazarian
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Breast cancer stands as the most prevalent form of cancer among women globally, influenced by a combination of genetic and environmental factors. Recent studies have investigated changes in microRNAs (miRNAs) during breast cancer progression and the
Externí odkaz:
https://doaj.org/article/0baf3b010760493db05d95a3babb21c2
Autor:
Behrouz Shademan, Vahidreza Karamad, Alireza Nourazarian, Sepideh Masjedi, Alireza Isazadeh, Fatma Sogutlu, Cigir Biray Avcı
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 3, Pp 435-445 (2023)
MicroRNAs are small RNAs with ability to attach to the large number of RNA that regulate gene expression on post-transcriptional level via inhibition or degradation of specific mRNAs. MiRNAs in cells are the primary regulators of functions such as ce
Externí odkaz:
https://doaj.org/article/96990c5346554d0ab23d002541771899
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 3, Pp 611-620 (2023)
Purpose: The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/ mTOR) pathway is a complex intracellular metabolic pathway that leads to cell growth and tumor proliferation and plays a key role in drug resistance in breast can
Externí odkaz:
https://doaj.org/article/df79b0320d7445379b5bdeb36f9d6307
Autor:
Samane Abbasi, Milad Asghari Totmaj, Masoumeh Abbasi, Saba Hajazimian, Pouya Goleij, Javad Behroozi, Behrouz Shademan, Alireza Isazadeh, Behzad Baradaran
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 7844-7858 (2023)
Abstract Over the last decade, the emergence of several novel therapeutic approaches has changed the therapeutic perspective of human malignancies. Adoptive immunotherapy through chimeric antigen receptor T cell (CAR‐T), which includes the engineer
Externí odkaz:
https://doaj.org/article/3b468603b3064fe4aad91f92bf5f65cd
Autor:
Elmira Roshani Asl, Sajed Sarabandi, Behrouz Shademan, Kourosh Dalvandi, Golshan sheikhansari, Alireza Nourazarian
Publikováno v:
Biochemistry and Biophysics Reports, Vol 35, Iss , Pp 101519- (2023)
Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enh
Externí odkaz:
https://doaj.org/article/e09acb1ad5b84fdd98617fbff6312f80
Autor:
Majid Tozihi, Behrouz Shademan, Hadi Yousefi, Cigir Biray Avci, Alireza Nourazarian, Gholamreza Dehghan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Cerebral ischemia-reperfusion (CIR) injury is initiated by the generation of reactive oxygen species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial event. The reperfusion process impairs critical cascades that
Externí odkaz:
https://doaj.org/article/eb079efc82c64118a1701410da6396f8
Autor:
Behrouz Shademan, Masoud Nikanfar, Jafar Rezaei, Mehdi Hassanpour, Mohammad Nouri, Alireza Nourazarian
Publikováno v:
Journal of Ardabil University of Medical Sciences, Vol 22, Iss 2, Pp 168-185 (2022)
Background & objectives: Evidence suggests that microRNAs (miRNAs) are essential for immune cell differentiation and function. In addition, miRNAs play an essential role in regulating the expression of pro-inflammatory genes in neurons. Therefore, we
Externí odkaz:
https://doaj.org/article/74148f45109442ed9aebde0b214a649f