Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.

Autor: Fowler SL; UK Dementia Research Institute at University College London, London, UK.; Oxford-GSK Institute of Molecular and Computational Medicine, University of Oxford, Oxford, UK., Behr TS; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Turkes E; UK Dementia Research Institute at University College London, London, UK., O'Brien DP; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Cauhy PM; UK Dementia Research Institute at University College London, London, UK., Rawlinson I; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Edmonds M; UK Dementia Research Institute at University College London, London, UK., Foiani MS; UK Dementia Research Institute at University College London, London, UK., Schaler A; Taub Institute, Irving Medical Center, Columbia University, New York, NY, USA., Crowley G; UK Dementia Research Institute at University College London, London, UK., Bez S; UK Dementia Research Institute at University College London, London, UK., Ficulle E; UK Dementia Research Institute at University College London, London, UK., Tsefou E; UK Dementia Research Institute at University College London, London, UK., Fischer R; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Geary B; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Gaur P; Department of Neurology, Center for Translational and Computational Neuroimmunology, Columbia University Medical Center, New York, NY, USA., Miller C; The Center for Genetic and Genomic Medicine, Hackensack University Medical Center, Hackensack, NJ, USA.; Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA., D'Acunzo P; Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA., Levy E; Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.; Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA., Duff KE; UK Dementia Research Institute at University College London, London, UK. k.duff@ucl.ac.uk.; Taub Institute, Irving Medical Center, Columbia University, New York, NY, USA. k.duff@ucl.ac.uk., Ryskeldi-Falcon B; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK. bfalcon@mrc-lmb.cam.ac.uk.

Publikováno v: Nature neuroscience [Nat Neurosci] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation.

Autor: Stephan T; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Brüser C; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Deckers M; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany., Steyer AM; Department of Neurogenetics, Electron Microscopy Core Unit, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Balzarotti F; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Barbot M; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Behr TS; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Heim G; Laboratory of Electron Microscopy, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Hübner W; Department of Physics, University Bielefeld, Bielefeld, Germany., Ilgen P; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Lange F; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Pacheu-Grau D; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany., Pape JK; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Stoldt S; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany., Huser T; Department of Physics, University Bielefeld, Bielefeld, Germany., Hell SW; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Goettingen, Goettingen, Germany., Möbius W; Department of Neurogenetics, Electron Microscopy Core Unit, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Rehling P; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Goettingen, Goettingen, Germany., Riedel D; Laboratory of Electron Microscopy, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Jakobs S; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Goettingen, Goettingen, Germany.

Publikováno v: The EMBO journal [EMBO J] 2020 Jul 15; Vol. 39 (14), pp. e104105. Date of Electronic Publication: 2020 Jun 22.