Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Behnaz Mojarrabi"'
Characterization of Two UDP Glucuronosyltransferases That Are Predominantly Expressed in Human Colon
Autor:
Peter I. Mackenzie, Behnaz Mojarrabi
Publikováno v:
Biochemical and Biophysical Research Communications. 247:704-709
The liver and gastrointestinal tract are major sites of drug metabolism. However, although the UDP glucuronosyltransferase family of drug-metabolizing enzymes has been extensively characterized in the liver, little is known about this family in the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915719b00941451757b422d5c7db7f3c
https://doi.org/10.1006/bbrc.1998.8843
https://doi.org/10.1006/bbrc.1998.8843
Autor:
Peter I. Mackenzie, Behnaz Mojarrabi
Publikováno v:
Biochemical and Biophysical Research Communications. 238:775-778
The cDNA encoding the UDP glucuronosyltransferase, UGT1A10, has been cloned from human colon. The deduced amino acid sequence of the cDNA is 90% similar in sequence to that of a previously characterized form, UGT1A9 (Hlug P4), and contains a signal p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771664913c9e71b4fffa49d50498f4e8
https://doi.org/10.1006/bbrc.1997.7388
https://doi.org/10.1006/bbrc.1997.7388
Publikováno v:
Comparative biochemistry and physiology. Toxicologypharmacology : CBP. 131(1)
The 11beta-hydroxysteroid dehydrogenases (11beta-HSDs) interconvert 11beta-hydroxysteroids such as cortisol into 11-oxosteroids such as cortisone. In most mammals, 11beta-HSD 1 is expressed predominantly in the liver and is active in both the oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24ca829813d3fe143c7079be22e1d95
https://pubmed.ncbi.nlm.nih.gov/11796324
https://pubmed.ncbi.nlm.nih.gov/11796324
Autor:
Mitchell D. Green, Peter I. Mackenzie, Gregory Zawada, Anna Radominska-Pandya, Birgit L. Coffman, Walter E. Gall, Thomas R. Tephly, Behnaz Mojarrabi
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 70(1-3)
In this work, UDP-glucuronosyltransferases (UGTs), UGT1A3, 2B7(H268) and 2B7(Y268), stably expressed in human embryonic kidney cells (HK293) were used to assess glucuronidation activities with a variety of steroid hormone and bile acid substrates. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc621ecc4bf8f4a5c38fe777fb660269
https://pubmed.ncbi.nlm.nih.gov/10529008
https://pubmed.ncbi.nlm.nih.gov/10529008
Autor:
Peter I. Mackenzie, Gladys R. Rios, Ziqiang Cheng, Thomas R. Tephly, Christopher D. King, Mitchell D. Green, Behnaz Mojarrabi, Birgit L. Coffman
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 45(1)
Catechol estrogens are major estrogen metabolites in mammals and are the most potent naturally occurring inhibitors of catecholamine metabolism. These estrogen compounds have been implicated in carcinogenic activity and the 4/2-hydroxyestradiol conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbfdc393a47f6699dd22ac92b597821
https://pubmed.ncbi.nlm.nih.gov/9848110
https://pubmed.ncbi.nlm.nih.gov/9848110
Autor:
P.T. Reeves, Candee H. Teitel, Behnaz Mojarrabi, Rodney F. Minchin, Fred F. Kadlubar, Michael E. McManus, Kenneth F. Ilett
Publikováno v:
Biochemical and biophysical research communications. 185(3)
Human monomorphic and polymorphic arylamine acetyltransferases (EC 2.3.1.5) were expressed in monkey kidney COS-1 cells and used to study the N- and O-acetylation of a number of carcinogenic amines and their N-hydroxy metabolites. The monomorphic enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115d5e108f3a0cbec9a3e4ef37e58d6b
https://pubmed.ncbi.nlm.nih.gov/1627140
https://pubmed.ncbi.nlm.nih.gov/1627140