Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Behnaz Bozorgui"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract The interactions between tumor intrinsic processes and immune checkpoints can mediate immune evasion by cancer cells and responses to immunotherapy. It is, however, challenging to identify functional interactions due to the prohibitively com
Externí odkaz:
https://doaj.org/article/e3473a9716454e91a6b8e5256dba5e5b
Autor:
Anil Korkut, Chris Sander, Scott Kopetz, Timothy A. Yap, Patrick G. Pilié, David G. Menter, Augustin Luna, Jacob H. Elnaggar, Parisa Imanirad, Behnaz Bozorgui, Zeynep Dereli, Gonghong Yan, Elisabeth K. Dowling, Xubin Li
Supplementary Table from Precision Combination Therapies Based on Recurrent Oncogenic Coalterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b0c3ddcfcc4c082091197c01886b3f
https://doi.org/10.1158/2159-8290.22541135
https://doi.org/10.1158/2159-8290.22541135
Autor:
Anil Korkut, Chris Sander, Scott Kopetz, Timothy A. Yap, Patrick G. Pilié, David G. Menter, Augustin Luna, Jacob H. Elnaggar, Parisa Imanirad, Behnaz Bozorgui, Zeynep Dereli, Gonghong Yan, Elisabeth K. Dowling, Xubin Li
Supplementary Data from Precision Combination Therapies Based on Recurrent Oncogenic Coalterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56948a7772330ad1338aa3a92fca8c28
https://doi.org/10.1158/2159-8290.22541174.v1
https://doi.org/10.1158/2159-8290.22541174.v1
Autor:
Anil Korkut, Chris Sander, Scott Kopetz, Timothy A. Yap, Patrick G. Pilié, David G. Menter, Augustin Luna, Jacob H. Elnaggar, Parisa Imanirad, Behnaz Bozorgui, Zeynep Dereli, Gonghong Yan, Elisabeth K. Dowling, Xubin Li
Cancer cells depend on multiple driver alterations whose oncogenic effects can be suppressed by drug combinations. Here, we provide a comprehensive resource of precision combination therapies tailored to oncogenic coalterations that are recurrent acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6621292947776bd8e421d927dbfecf67
https://doi.org/10.1158/2159-8290.c.6549560
https://doi.org/10.1158/2159-8290.c.6549560
Supplementary Figure from Precision Combination Therapies Based on Recurrent Oncogenic Coalterations
Autor:
Anil Korkut, Chris Sander, Scott Kopetz, Timothy A. Yap, Patrick G. Pilié, David G. Menter, Augustin Luna, Jacob H. Elnaggar, Parisa Imanirad, Behnaz Bozorgui, Zeynep Dereli, Gonghong Yan, Elisabeth K. Dowling, Xubin Li
Supplementary Figure from Precision Combination Therapies Based on Recurrent Oncogenic Coalterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405a813b47ab9906d7cce9d6694e4550
https://doi.org/10.1158/2159-8290.22541171.v1
https://doi.org/10.1158/2159-8290.22541171.v1
Publikováno v:
Cancer Research. 83:3144-3144
The interactions between tumor intrinsic processes and immune checkpoints can mediate the immune evasion by tumors and responses to immunotherapy. It is, however, challenging to identify functional interactions due to the prohibitively complex molecu
The interactions between tumor intrinsic processes and immune checkpoints can mediate immune evasion by cancer cells and responses to immunotherapy. It is, however, challenging to identify functional interactions due to the prohibitively complex mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5599390668d2dbaaf4d8e542f321948
https://doi.org/10.1101/2021.10.06.462889
https://doi.org/10.1101/2021.10.06.462889
Autor:
Xubin Li, Elisabeth K. Dowling, Gonghong Yan, Zeynep Dereli, Behnaz Bozorgui, Parisa Imanirad, Jacob H. Elnaggar, Augustin Luna, David G. Menter, Patrick G. Pilié, Timothy A. Yap, Scott Kopetz, Chris Sander, Anil Korkut
Publikováno v:
Cancer Discov
Cancer cells depend on multiple driver alterations whose oncogenic effects can be suppressed by drug combinations. Here, we provide a comprehensive resource of precision combination therapies tailored to oncogenic coalterations that are recurrent acr
Autor:
Anil Korkut, Xubin Li, Elizabeth Kong, Gonghong Yan, Zeynep Dereli, Behnaz Bozorgui, Parisa Imanirad, Jacob Elnaggar, Augustin Luna, David Menter, Patrick Pilié, Timothy Yap, Scott Kopetz, Chris Sander
Publikováno v:
Cancer Research. 82:LB119-LB119
Cancer cells depend on multiple driver alterations whose oncogenic effects can be suppressed by drug combinations. Discovering effective combination therapies and selecting patients to maximize therapeutic benefit are challenging due to the complexit
Autor:
Gonghong Yan, Augustin Luna, Heping Wang, Behnaz Bozorgui, Xubin Li, Maga Sanchez, Zeynep Dereli, Nermin Kahraman, Goknur Kara, Xiaohua Chen, Caishang Zheng, Daniel McGrail, Nidhi Sahni, Yiling Lu, Ozgun Babur, Murat Cokol, Bora Lim, Bulent Ozpolat, Chris Sander, Gordon B. Mills, Anil Korkut
Publikováno v:
Cell reports. 40(11)
Therapeutic options for treatment of basal-like breast cancers remain limited. Here, we demonstrate that bromodomain and extra-terminal (BET) inhibition induces an adaptive response leading to MCL1 protein-driven evasion of apoptosis in breast cancer