Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Behjat Moayedi"'
Publikováno v:
Clinical Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Abnormal iron accumulation in vital organs is one of the major complications of β‐thalassemia intermedia (β‐TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β‐TI pa
Externí odkaz:
https://doaj.org/article/50e794201544470aa20ea5dc3f8704ac
Autor:
Vahid Shaygannejad, Faezeh Abbasirad, Behzad Mahaki, Fahimeh Hosseininasab, Nafiseh Esmaeil, Behjat Moayedi, Omid Mirmosayyeb
Publikováno v:
International immunopharmacology. 97
Interferon beta (IFN-β) has successfully been experimented with to treat multiple sclerosis (MS). However, patients sometimes do not respond effectively to treatment, and â��adverse effects, including liver toxicity, accompany this therapy. â
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbf51b905c93dba223b2e188a927691
https://pubmed.ncbi.nlm.nih.gov/33933848
https://pubmed.ncbi.nlm.nih.gov/33933848
Publikováno v:
International Immunopharmacology. 50:194-201
Silymarin is a flavonoid complex extracted from the Silybum marianum plant. It acts as a strong antioxidant and free radical scavenger by different mechanisms. But in addition to antioxidant effects, silymarin/silybin reveals immunomodulatory affects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf2db180eef4739fce426524f07828f
https://doi.org/10.1016/j.intimp.2017.06.030
https://doi.org/10.1016/j.intimp.2017.06.030
Autor:
Milad Mirmoghtadaei, Marjan Gharagozloo, Mahdi Ghatreh Samani, Nafiseh Esmaeil, Behjat Moayedi
Publikováno v:
Journal of Advances in Medical and Pharmaceutical Sciences. 2:52-56
Background: Despite appropriate chelation therapy with desferrioxamine, iron deposition in visceral organs causes tissue damage in thalassemia major patients. Excess iron can generate reactive oxygen species (ROS) that may lead to cell death and apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed7610ebce24db36aa23266f079fac4
https://doi.org/10.9734/jamps/2015/12818
https://doi.org/10.9734/jamps/2015/12818
Autor:
Mohammadmorad Farajollahi, Behjat Moayedi, Milad Mirmoghtadaei, Mahmoud Reza Alebouyeh, Hossein Rastegar, Maryam Ahmadzadeh, Mojgan Taghizadeh Manzari, Farzad Parvizpour, Safoora Gharibzadeh, Saieh Hajighasemlou, Mansure Kazemi
Publikováno v:
Advances in Breast Cancer Research. :100-105
Background: Breast cancer is the most prevalent cancer and results in 14% of cancer-related deaths among women worldwide. The aim of this study is to investigate the anticancer effects of Silymarin on two breast cancer cell lines (BT-474, SK-BR-3). M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be56e43648cbab4a3689ef978d368cdc
https://doi.org/10.4236/abcr.2014.33015
https://doi.org/10.4236/abcr.2014.33015
Publikováno v:
Hemoglobin. 37:404-410
Deposition of iron in visceral organs, mainly in the liver, causes tissue damage in β-thalassemia major (β-TM) patients. Keratin 18 (K18) represents one of the major caspase substrates during apoptosis of hepatocytes. To better characterize the hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca55ee3c3283ec86311a29adff1be590
https://doi.org/10.3109/03630269.2013.790828
https://doi.org/10.3109/03630269.2013.790828
Autor:
Behjat Moayedi, Hamid Hoorfar, Mohammad Reza Maracy, Marjan Gharagozloo, Mohsen Jalaeikar, Nafiseh Esmaeil
Publikováno v:
European Journal of Haematology. 90:202-209
Objective Thalassemia is one of the most common genetic disorders worldwide. Chronic blood transfusions treat the underlying anemia but may lead to iron toxicity. Effective iron chelation remains one of the main targets of clinical management of thal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d541271a949c1d3385dd9b43902ebe6
https://doi.org/10.1111/ejh.12061
https://doi.org/10.1111/ejh.12061
Autor:
Zahra Amirghofran, Farzad Oreizy, Hamid Hourfar, Marjan Gharagozloo, Mahmoud Tahanian, Behjat Moayedi, Heydar Sadeghi, Bahram Bagherpour
Publikováno v:
Immunology Letters. 122:84-88
Several researches have demonstrated a suppressed cell mediated immunity in patients with beta-thalassemia major. To know whether the premature aging of T cells is involved in abnormalities of cell mediated immunity, the biomarkers of immunosenescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659d27ccc3f1d1935fb1ee50c41e0e38
https://doi.org/10.1016/j.imlet.2008.12.003
https://doi.org/10.1016/j.imlet.2008.12.003
Autor:
Seyed Ebrahim Sajjadi, Behjat Moayedi, Hamid Hourfar, Fariba Alidoost, Bahram Bagherpour, Marjan Gharagozloo, Abbas Jafarian
Publikováno v:
International Immunopharmacology. 6:1305-1310
Iron toxicity in beta-thalassemia major is the main cause of oxidative stress and cell mediated immune deficiencies. Despite indicative signs of severe oxidative deficiencies associated with beta-thalassemia major, such as decreased level of plasma a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c03b93e4f65837f1325929e99cf459
https://doi.org/10.1016/j.intimp.2006.04.004
https://doi.org/10.1016/j.intimp.2006.04.004
Publikováno v:
Immunopharmacology and immunotoxicology. 36(4)
Several immunological abnormalities have been characterized in β-thalassemia, many of which are linked to or identified with cytokines. In this study, we investigated the serum levels of TGF-β, IL-10, IL-17 and IL-23 in β-thalassemia major patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21d6ff9c928dcf792455655e81ddeb2
https://pubmed.ncbi.nlm.nih.gov/24945737
https://pubmed.ncbi.nlm.nih.gov/24945737